A5031341088- Voice and Speech Disorders
- Dysphagia Assessment and Management
- Tracheal and airway disorders
- Respiratory and Cough-Related Research
- Gastroesophageal reflux and treatments
- Phonetics and Phonology Research
- Speech Recognition and Synthesis
- Airway Management and Intubation Techniques
- Eosinophilic Esophagitis
- Head and Neck Surgical Oncology
- Asthma and respiratory diseases
- Head and Neck Cancer Studies
- Clinical practice guidelines implementation
- Helicobacter pylori-related gastroenterology studies
- Respiratory Support and Mechanisms
- Salivary Gland Tumors Diagnosis and Treatment
- Foreign Body Medical Cases
- Oral Health Pathology and Treatment
- Vascular Anomalies and Treatments
- Ear and Head Tumors
- Medical Research and Practices
- Cancer Treatment and Pharmacology
- Economic and Financial Impacts of Cancer
- Non-Invasive Vital Sign Monitoring
- Delphi Technique in Research
Nottingham University Hospitals NHS Trust
2016-2025
Macquarie University
2024
Queen's Medical Centre
2009-2023
Massachusetts General Hospital
2023
University of Nottingham
2004-2021
Paediatric Integrated Cancer Service
2016
Alfred Health
2016
University of North Carolina at Chapel Hill
2011
Medical College of Wisconsin
2011
Newcastle University
2011
Abstract Objective To assess the use of proton pump inhibitors (PPIs) to treat persistent throat symptoms. Design Pragmatic, double blind, placebo controlled, randomised trial. Setting Eight ear, nose, and outpatient clinics, United Kingdom. Participants 346 patients aged 18 years or older with symptoms who were according recruiting centre baseline severity (mild severe): 172 lansoprazole 174 placebo. Intervention Random blinded allocation (1:1) either 30 mg twice daily matched for 16 weeks....
Introduction Persistent throat symptoms (PTS) are indicators for over 60 000 new patient referrals to NHS secondary care annually. PTS have been attributed manifestation of gastro-oesophageal reflux disease (GORD) with the hypothesis that gastric refluxate damages and irritates mucosa upper aerodigestive tract. Symptoms GORD commonly treated proton pump inhibitors (PPIs) or alginates often, incorrectly, advocated. The Trial PPIs in Throat trial definitively demonstrated lansoprazole is no...
Objective: Supraglottic structures can be used as a sound source in both pathological and healthy voice production. In professional users, supraglottic vibration phenotypes have been previously identified; however, at present, no reviews integrating literature on the topic are available. This narrative review provides an integrative to develop taxonomy of sources, including distinguishing vibrational strategy, level control, number vibrating phenotypes. Method: study extant use users into...
Unlike gastro-oesophageal reflux, extra-oesophageal reflux (EOR) is not necessarily associated with heartburn. The potential prevalence of EOR in general practice the UK using Reflux Symptom Index (RSI) questionnaire was determined. A total 1152 patients attending a GP surgery for routine conditions completed RSI questionnaire: 26.5% had an score >10, regarded as clinically significant EOR; 29% rated impact heartburn previous month zero. Significant numbers presenting to GPs have high scores...
Summary A 79‐year‐old man with a diagnosis of myocardial infarction treated streptokinase and heparin developed large lingual haematoma, precipitating dysphagia upper airway obstruction. Spontaneous haemorrhage into the tongue is previously unreported but serious complication thrombolytic therapy. Tracheal intubation was performed under local anaesthesia.
Introduction: Traditionally, fundamental frequency increase has been viewed as largely associated with vocal fold length a consequence of tilting the thyroid cartilage forward and downwards, so-called tilt, caused by cricothyroid muscle contraction. Recent pilot studies in singers suggest elongation independent from fo related to pedagogical parameter called ‘phonatory density’, suggesting further discrete mechanism tilt voice quality. This study endoscopically, EGG, acoustically,...
These guidelines, informed by the best available evidence and consensus expert opinion, provide a framework to guide timely initiation of chemotherapy for treating cancer. They sit at intersection patient experience, state-of-the-art disease management rational efficient service provision these patients system level. Internationally, cancer waiting times are routinely measured publicly reported. In Australia, there existing policies guidelines relating timeliness care surgery radiation...
Background Persistent throat symptoms are commonly attributed to ‘laryngopharyngeal reflux’. Despite a limited evidence base, these increasingly being treated in primary care with proton pump inhibitors. Objective To assess the value of inhibitor therapy patients persistent symptoms. Design This was double-blind, placebo-controlled, randomised Phase III trial. Setting multicentre UK trial eight ear, nose and departments. Participants A total 346 participants aged ≥ 18 years Reflux Symptom...
Abstract Background Management of benign vocal fold lesions (BVFLs) is variable with individuals receiving surgery, voice therapy, or a combination these approaches. Some evidence suggests that the best outcomes may be achieved when patients are offered pre- and post-operative therapy in addition to phonosurgery, but what constitutes poorly described. The (PAPOV) intervention has been developed described according TIDieR checklist Rehabilitation Treatment Specification System (RTSS) for...
Multiple myeloma involving the thyroid cartilage is a very uncommon disease entity. Only 10 cases have been reported in international literature to date and as such it constitutes rare challenging diagnosis make. We report case of 63-year-old man with background malignant melanoma multiple both which were remission at time presentation. The patient presented hoarseness large neck mass that turned out be an extramedullary deposit his previously treated indicating relapse. differential...