- Parathyroid Disorders and Treatments
- Neurological and metabolic disorders
- Vitamin D Research Studies
- Renal Diseases and Glomerulopathies
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Cerebrospinal fluid and hydrocephalus
- Systemic Sclerosis and Related Diseases
- Magnesium in Health and Disease
- Eosinophilic Disorders and Syndromes
- Genetic and Kidney Cyst Diseases
- Blood properties and coagulation
- Dialysis and Renal Disease Management
- Platelet Disorders and Treatments
- Immunodeficiency and Autoimmune Disorders
- Kruppel-like factors research
- Genetic Syndromes and Imprinting
- Pharmacological Effects and Toxicity Studies
- Diabetes Treatment and Management
- Inflammatory Myopathies and Dermatomyositis
- Autoimmune Bullous Skin Diseases
- Renal and related cancers
- Tuberous Sclerosis Complex Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Fibroblast Growth Factor Research
Showa University
2017-2023
Saiseikai Nakatsu Hospital
2022
Showa University Koto Toyosu Hospital
2018
Japan Organization of Occupational Health and Safety
2016
Abstract We present six cases of antimelanoma differentiation‐associated gene 5 antibody (anti‐MDA5‐Ab)‐positive clinically amyopathic dermatomyositis (CADM) with rapidly progressive interstitial lung disease (RP‐ILD), which is known to have a poor prognosis. The outcomes these are described after treatment therapeutic plasma exchange (TPE). Clinical and data for patients CADM RP‐ILD were collected retrospectively from medical records. All received early intensive care including high‐dose...
Calciphylaxis, a multifactorial cutaneous vascular disease, is rare but therapy-resistant and life-threatening disorder that usually occurs in patients with end-stage kidney disease (ESKD). Although there have been many reports regarding calciphylaxis, its pathophysiology not fully understood strong evidence for treatment lacking. A 63-year-old woman 20-year history of hemodialysis (HD) ESKD unknown etiology was admitted because severe painful ulcers on the right lower leg. She underwent...
Serum soluble Klotho levels are associated with renal function in predialysis patients chronic kidney disease. However, few reports exist regarding the association between and transplant (KTx) recipients. This was a retrospective observational study of 41 living KTx The serum were classed as "high" (>456 pg/mL [i.e., high-Klotho group]) or "low" (≤456 low-Klotho group]). Renal decline defined decrease estimated glomerular filtration rate (eGFR) 30% more from baseline value within 3 months...
Backgrounds: Fibroblast growth factor 23 (FGF23) is associated with cardiovascular disease in patients chronic kidney (CKD), but the mechanisms underlying effect of FGF23 on cardiac function remain to be investigated. Herein, we studied continuous intravenous (CIV) loading a deoxycorticosterone acetate (DOCA)-salt mouse model that has mild CKD and hypertension, heart failure preserved ejection fraction (HFpEF). Design method: Wild type male mice (n = 16) were allocated randomly four groups:...
Aspergillus fumigatus (Af) is a ubiquitous fungus in our environment that causes severe airway disorders.Chronic respiratory diseases (CRDs) comprise various upper and lower disorders ranging from asthma, chronic obstructive pulmonary disease, lung fibrosis, allergic rhinitis, among others.Fungal colonization or infection thought to play major role the initiation exacerbation of CRDs.However, relationship between Af CRDs remains unclear.We examined 104 samples species (spp.)isolated January...