A5045894964- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Plant-Microbe Interactions and Immunity
- Plant Pathogens and Fungal Diseases
- Fungal and yeast genetics research
- Parasitic Diseases Research and Treatment
- Mycobacterium research and diagnosis
- Carbohydrate Chemistry and Synthesis
- Tuberculosis Research and Epidemiology
- Plant pathogens and resistance mechanisms
- Natural product bioactivities and synthesis
- Gut microbiota and health
- Antimicrobial Peptides and Activities
- Galectins and Cancer Biology
- Enterobacteriaceae and Cronobacter Research
- Studies on Chitinases and Chitosanases
Universidad de Guanajuato
2017-2024
Fungal infections are a serious and increasing threat for human health, one of the most frequent etiological agents systemic mycoses is Candida spp. The gold standard to assess virulence mouse model candidiasis, restrictive, expensive, time-consuming approach; therefore, invertebrate models have been proposed as alternatives. Galleria mellonella larvae several traits that make them good candidates study fungal virulence. Here, we showed reduction in circulating hemocytes, increased melanin...
Phosphomannosylation is a modification of cell wall proteins that occurs in some species yeast-like organisms, including the human pathogen Candida albicans. These modified mannans confer negative charge to wall, which important for interactions with phagocytic cells immune systems and cationic antimicrobial peptides. In Saccharomyces cerevisiae, synthesis phosphomannan relies on two enzymes, phosphomannosyltransferase Ktr6 its positive regulator Mnn4. However, C. albicans, at least three...
Sporotrichosis is a fungal disease caused by the members of Sporothrix pathogenic clade, and one etiological agents schenckii. The cell wall this organism has been previously analyzed thus far known to contain an inner layer composed chitin β -glucans, outer glycoproteins, which are decorated with mannose rhamnose-containing oligosaccharides. L-rhamnose biosynthesis pathway common in bacteria but rare Fungi kingdom. Therefore, study, we aimed disrupt metabolic route assess contribution...