A5100403086- RNA Interference and Gene Delivery
- Peptidase Inhibition and Analysis
- Nanoparticle-Based Drug Delivery
- Lung Cancer Research Studies
- Phytochemistry and Biological Activities
- Phytochemistry and Bioactive Compounds
- biodegradable polymer synthesis and properties
- Drug Transport and Resistance Mechanisms
- Bone Tissue Engineering Materials
- Photopolymerization techniques and applications
- Magnesium Alloys: Properties and Applications
- Orthopaedic implants and arthroplasty
- Pigment Synthesis and Properties
- Natural product bioactivities and synthesis
Jiangsu Agri-animal Husbandry Vocational College
2022
Chinese PLA General Hospital
2022
Huazhong University of Science and Technology
2017-2018
Union Hospital
2018
Objectives. In this study, a new type of dental implant by covering the surface titanium (Ti) with zinc-magnesium (Zn-Mg) alloy was designed, to study antibacterial and antioxidant effects Mg on implants in oral restoration. Methods. Human gingival fibroblasts (HGFs), S. sanguinis, F. nucleatum bacteria were used detect bioactivity properties alloy-coated Ti implants. addition, B6/J mice implanted different materials further their properties. Results. The results showed that could better...
T cell acute lymphoblastic leukemia (T-ALL) is caused by clonal expansion of variant progenitors and considered as a high risk leukemia. Contemporary single chemotherapy has limited effect due to dynamic versatile properties T-ALL. Here IRAK1/4 inhibitor ABT-737 were co-encapsulated into polyethylene glycol modified poly (lactic-co-glycolic acid) nanoparticles (IRAK/ABT-NP) enhance synergistic therapy The formulation was optimized achieve drug loading using Box-Behnken design response...
Poly(L-lactic acid) (PLLA) as an important biodegradable polymer suffers from slow crystallization rate and poor heat resistance. An organic compound N,N’-dodecanedioic bis(3-phenylpropionic dihydrazide (BHADD) was synthesized to evaluate its general influences on the physical properties of PLLA. The melt-crystallization process indicated that BHADD could serve a heterogeneous nucleating agent for improving PLLA, PLLA/1%BHADD exhibited sharpest peak located at highest temperature, well...