A5100375613- Spine and Intervertebral Disc Pathology
- Coronary Interventions and Diagnostics
- Spinal Fractures and Fixation Techniques
- Epilepsy research and treatment
- Nanoparticle-Based Drug Delivery
- Medical Imaging and Analysis
- Innovations in Medical Education
- Hepatocellular Carcinoma Treatment and Prognosis
- Air Quality and Health Impacts
- Anesthesia and Pain Management
- Cervical and Thoracic Myelopathy
- Tissue Engineering and Regenerative Medicine
- MRI in cancer diagnosis
- Peripheral Artery Disease Management
- Musculoskeletal pain and rehabilitation
- Neonatal and fetal brain pathology
- Electrospun Nanofibers in Biomedical Applications
- Radiomics and Machine Learning in Medical Imaging
- Pharmacological Effects and Toxicity Studies
- Advanced MRI Techniques and Applications
- Head and Neck Surgical Oncology
- Spinal Hematomas and Complications
- Neuroscience and Neuropharmacology Research
- Lung Cancer Treatments and Mutations
- Carcinogens and Genotoxicity Assessment
Chinese Academy of Medical Sciences & Peking Union Medical College
2017-2025
General Hospital of Shenyang Military Region
2017-2024
Peking University First Hospital
2022-2024
Peking University
2022-2024
Columbia University
2009-2024
Northeast Forestry University
2024
Georgia Institute of Technology
2024
First Hospital of Jilin University
2019-2024
Jilin University
2019-2024
Nanjing Medical University
2024
This study evaluated the relationship between prenatal exposure to airborne polycyclic aromatic hydrocarbons (PAHs) and child intelligence.
Airborne polycyclic aromatic hydrocarbons (PAH) are widespread urban air pollutants from fossil fuel burning and other combustion sources. We previously reported that a broad spectrum of combustion-related DNA adducts in cord blood was associated with attention problems at 6-7 years age the Columbia Center for Children's Environmental Health (CCCEH) longitudinal cohort study.We evaluated relationship between behavioral two different measures prenatal exposure--both specific to PAH--in same...
In this prospective cohort study of Caucasian mothers and children in Krakow, Poland, we evaluated the role prenatal exposure to urban air pollutants pathogenesis neurobehavioral disorders.
Background: Airborne polycyclic aromatic hydrocarbons (PAH) are widespread urban pollutants that can bind to DNA form PAH–DNA adducts. Prenatal PAH exposure measured by personal monitoring has been linked cognitive deficits in childhood a prospective study conducted the Columbia Center for Children's Environmental Health.Objectives: We and other bulky adducts umbilical cord white blood cells using 32P-postlabeling assay determine association between this molecular dosimeter...
To measure the interobserver reproducibility and intra-observer of subfoveal choroidal thickness measurements performed by enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT) in a population-based setting.The Beijing Eye Study 2011 was study rural urban regions Greater Beijing. The included 3468 individuals with mean age 64.6 ± 9.8 years (range, 50-93 years). participants underwent EDI-OCT (SFCT) measured. examine variability, all images were assessed two examiners...
Previous studies have found that percutaneous vertebroplasty (PVP) can effectively improve the local pain of affected vertebra caused by thoracolumbar osteoporotic vertebral compression fracture (OVCF) regardless unilateral or bilateral puncture, but there are few reports on whether it is equally effective for accompanying distant lumbosacral pain. To analyze clinical effect PVP OVCF with The data patients single-stage treated in our hospital from March 2019 to 2023 were retrospectively...
MRI-negative (MRI-) pharmacoresistant focal epilepsy (PFE) patients are most challenging for surgical management. This study utilizes a voxel-based MRI postprocessing technique, implemented using morphometric analysis program (MAP), aiming to facilitate detection of subtle cortical dysplasia (FCD) in MRI- patients. Furthermore, the examines concordance between MAP-identified regions and localization from magnetic source imaging (MSI).Included this retrospective were 25 MAP was performed on...
Abstract Construction of simple and efficient protein adsorption materials is extremely vital to satisfy the requirements highly purified proteins in biopharmaceutical biotechnological industries, yet remains challenging. Herein, a cost‐effective strategy develop seaweed‐derived nanofibrous membranes (NFM) for ultrahigh reported. Synergistic regulation by cosolvent ethanol, nonionic surfactants Triton X‐100, polyethylene oxide (PEO 5000k ) employed realize electrospinning sodium alginate...
Abstract Purpose This study evaluated the clinical safety and efficacy of tanfanercept (HBM9036) ophthalmic solution as a novel treatment for dry eye disease (DED) in controlled adverse environment (CAE) conducted China. Methods In single-center, double-masked, randomized, placebo-controlled study, 100 patients received 0.25% tanfanercept, or placebo, twice daily eight weeks. A mobile international CAE ® DE Model was used patient selection with standardized challenge endpoint. Primary...
Abstract Aims To investigate the clinical characteristics, surgical strategy, developmental and seizure outcomes, predictors of outcome in children with drug‐resistant epilepsy (DRE) under 3 years old. Methods One hundred thirteen consecutive younger than age DRE underwent curative treatment after multidisciplinary preoperative evaluation using strategy developed pediatric center Peking University First Hospital (PKFHPEC) between 2014 2018. These patients were selected for retrospective...
Objective: To evaluate the clinical efficacy, practicability, and safety of an ultrasonic osteotome for percutaneous transforaminal endoscopic discectomy (PTED) in patients with calcified lumbar disc herniation (CLDH).Methods: A total 25 CLDH who underwent PTED at our department between December 2017 August 2018 were analyzed retrospectively. Post-operative spine CT was used to residual calcification. Efficacy evaluated by pre- post-operative pain visual analog scale (VAS), Oswestry...
To investigate the value of radiomics features derived from preoperative multi-sequence MR images for predicting early recurrence (ER) in patients with solitary hepatocellular carcinoma (HCC) ≤5 cm.One hundred and ninety HCC were enrolled allocated to training validation sets (n = 133:57). The clinical-radiological model was established by significant clinical risk characteristics qualitative imaging features. constructed using least absolute shrinkage selection operator (LASSO) logistic...
Abstract Objective To investigate the value of ultrasonography in diagnosis heterotopic pregnancy and follow‐up. Methods A retrospective analysis 50 cases clinically diagnosed our hospital was performed, clinical characteristics ultrasonographic manifestations patients were summarized, reasons for initial ultrasound missed misdiagnosis analyzed, outcomes followed up. Results Among cases, diagnoses intrauterine all gestational sac type, 32 ectopic located fallopian tube, 10 uterine horn, 1...