Cihan Gündoğan

ORCID: 0000-0001-5700-6292
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About
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Research Areas
  • Medical Imaging Techniques and Applications
  • Radiomics and Machine Learning in Medical Imaging
  • Peptidase Inhibition and Analysis
  • Protease and Inhibitor Mechanisms
  • Radiopharmaceutical Chemistry and Applications
  • Cardiac Structural Anomalies and Repair
  • Prostate Cancer Treatment and Research
  • Lymphoma Diagnosis and Treatment
  • MRI in cancer diagnosis
  • Lung Cancer Diagnosis and Treatment
  • Neuropeptides and Animal Physiology
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • Thyroid Cancer Diagnosis and Treatment
  • Head and Neck Cancer Studies
  • Lung Cancer Treatments and Mutations
  • Prostate Cancer Diagnosis and Treatment
  • Cardiac Imaging and Diagnostics
  • Cancer Diagnosis and Treatment
  • Renal cell carcinoma treatment
  • Bladder and Urothelial Cancer Treatments
  • Cell Adhesion Molecules Research
  • Cancer Immunotherapy and Biomarkers
  • Colorectal Cancer Surgical Treatments
  • Traumatic Brain Injury and Neurovascular Disturbances

Diyarbakır Gazi Yaşargil Eğitim ve Araştırma Hastanesi
2020-2024

Sağlık Bilimleri Üniversitesi
2019-2024

University of Health Science
2021-2024

University of Health Sciences
2021-2023

Committee on Publication Ethics
2020

Education Training And Research
2019

Istanbul University
2019

Ministry of Health
2016

Objective In this study, we aimed to evaluate the diagnostic sensitivities of 68 Ga-FAPI-04 PET/CT and 18 F-FDG in primary tumor, nodal, peritoneal distant organ metastases recurrent gastric adenocarcinoma (GAc) with patient lesion-based comparison. Materials method Twenty-one patients histopathologically proven newly diagnosed or GAc who underwent imaging were included study. Both techniques evaluated visually according intensity organ-based uptake. SUVmax tumor-to-background ratio (TBR)...

10.1097/mnm.0000000000001489 article EN Nuclear Medicine Communications 2021-10-05

68Ga-fibroblast activation protein-specific inhibitor (FAPI)-04 PET/CT was performed in a 49-year-old woman diagnosed with breast cancer. In imaging, intense 68Ga-FAPI uptake observed the primary tumor, axillary lymph nodes, and also thyroid gland, whereas pathological 18F-FDG not gland. On ultrasonography, parenchyma heterogeneous, an area of focal thyroiditis superior part right lobe. Biochemical parameters were found to be consistent thyroiditis. This case shows that FAPI gland may...

10.1097/rlu.0000000000003637 article EN Clinical Nuclear Medicine 2021-04-07

In this study, we aimed to compare the diagnostic accuracy of 18 F-fluorodeoxyglucose ( F-FDG) and Gallium-68 labeled fibroblast activator protein inhibitor 68 Ga-FAPI)-04 PET/CT in tumor-node-metastasis (TNM) staging patients with nonsmall cell lung cancer (NSCLC) investigate whether adenocarcinoma (ADC) squamous (SCC) exhibit different uptake patterns on Ga-FAPI-04 PET/CT.Twenty-nine a histopathologically-confirmed diagnosis NSCLC, who had no history previous radiation therapy or...

10.1097/mnm.0000000000001607 article EN Nuclear Medicine Communications 2022-08-16

68Ga-FAPI (fibroblast activation protein-specific inhibitor) PET/CT was performed in a 56-year-old man with multiple liver masses, which were confirmed grade 2 well-differentiated neuroendocrine tumors Tru-Cut biopsy. With 68Ga-DOTATE PET/CT, primary tumor the pancreas, metastases and metastatic portocaval lymph node detected. In imaging for comparison, it seen that lesions distinguished much better because of low background activity, clearly selected. This case suggested FAPI-bounded...

10.1097/rlu.0000000000003490 article EN Clinical Nuclear Medicine 2020-12-22

Abstract 68 Ga-fibroblast activation protein-specific inhibitor (FAPI)-04 PET/CT was performed in a patient with left lower outer quadrant breast cancer who had 18 F-FDG imaging. Ga-FAPI-04 showed higher accumulation of radiotracer primary tumor and axillary lymph nodes than PET/CT. In addition, focal increased FAPI uptake observed another nodular lesion the inner same breast, which considered malignant. However, Tru-Cut biopsy this reported as benign lymphoid tissue. This case that all...

10.1097/rlu.0000000000003594 article EN Clinical Nuclear Medicine 2021-03-30

Objective. The aim of this study is to investigate the uptake 68Ga-FAPI-04 in normal tissues and calculate standardized values (SUVs) for various organs body. Methods. A total 49 patients who underwent PET/CT were included our study. following identified on CT images: brain, parotid, submandibular glands, palatine tonsils, thyroid, lymph nodes (if present), breasts, lungs, thymus, left ventricle walls, mediastinal blood pool, vertebral bone marrow, liver, spleen, pancreas, stomach, small...

10.1155/2021/9750080 article EN Contrast Media & Molecular Imaging 2021-11-23

Objectives: This study aimed to compare the metabolic parameters obtained from 18 fluorine-fluorodeoxyglucose ( F-FDG) positron emission tomography/computed tomography (PET/CT) and gallium-68 68 Ga)-prostate-specific membrane antigen (PSMA) PET/CT investigate relationship between serum alpha-fetoprotein PET scan in patients with hepatocellular carcinoma.Methods: Fourteen were recruited after dynamic magnetic resonance imaging (MRI) of upper abdomen, F-FDG Ga-PSMA studies conducted.Regions...

10.4274/mirt.galenos.2021.92053 article EN Molecular Imaging and Radionuclide Therapy 2021-06-01

Abstract An 83-year-old man presented with abdominal pain, vomiting, and bloating. His CT revealed heterogeneous peritoneal thickening in the lower quadrants, which was more prominent pelvic region. 18 F-FDG PET/CT performed to locate primary tumor showed irregular omental low moderate FDG uptake. 68 Ga–FAPI (fibroblast activation protein–specific inhibitor)–04 of patient, whose could not be detected using FDG, high radiopharmaceutical uptake areas on serosal surfaces. Peritoneal Tru-Cut...

10.1097/rlu.0000000000003858 article EN Clinical Nuclear Medicine 2021-08-13

AIM: The aim of this study is to evaluate the diagnostic value PET-CT scan for prediction EGFR mutation status and contribution TTF-1 expression scan. METHODS: We retrospectively studied 218 cases with a diagnosis pulmonary adenocarcinoma between 2012-2014 which underw ent analysis, before treatment. RESULTS: was present in 28.9% (n= 63) cases. positivity 66.9% 105). Standardized uptake (SUV max) 16.7 ± 6.8 mutant type, 13.8 7.6 having no mutations. According our evaluations, high SUVmax...

10.3233/cbm-160588 article EN Cancer Biomarkers 2016-03-30

We aimed to examine the effect of a history COVID-19 on myocardial ischemia in single-photon emission computed tomography (SPECT) perfusion imaging (MPI) patients who presented with shortness breath and/or chest pain after recovery. For this single-center retrospective study, at cardiology outpatient clinics and had SPECT-MPI were screened. A total 1888 included 340 whom COVID-19. 64 > 50% stenosis coronary angiography excluded from study. The primary outcome study was abnormal MPI. In...

10.1007/s10554-021-02477-9 article EN other-oa The International Journal of Cardiovascular Imaging 2021-11-22

In this study, we aimed to compare the role of 68 Ga-labeled FAP inhibitor ( Ga-FAPI)-04 PET/computed tomography (CT) and 18 F-fluorodeoxyglucose F-FDG) PET/CT in evaluation primary tumor metastases patients diagnosed with malignant mesothelioma.Our prospective study included 21 histopathological diagnosis mesothelioma who underwent both Ga-FAPI-04 F-FDG imaging between April 2022 September 2022. Maximum standardized uptake value (SUVmax), metabolic volume, total lesion glycolysis,...

10.1097/mnm.0000000000001702 article EN Nuclear Medicine Communications 2023-04-28

This study aimed to determine whether intravenous contrast-enhanced dual-phase fluorine-18--fluorodeoxyglucose (F-FDG) PET/CT scans provide additional diagnostic information compared with the MRI/CT in patients laryngeal carcinoma during initial staging.Forty-five consecutive (44 men, one woman; mean age±SD, 67.0±9.0 years, range: 45-80 years) of larynx who had and were enrolled. Each patient was scanned on system 1 h (early) 2 (delayed) after injection. The maximum standardized uptake...

10.1097/mnm.0000000000000809 article EN Nuclear Medicine Communications 2018-03-13

Objectives: Several studies demonstrate the relationship between coronary artery disease and inflammatory parameters.Nevertheless, there is paucity of data regarding role high sensitivity (hs)-C-reactive protein (CRP) to albumin ratio (CAR) in patients with ischemia on gated single photon emission tomography (SPECT) myocardial perfusion imaging (MPI).This study was aimed at demonstrating CAR occurrence SPECT MPI.Methods: We retrospectively evaluated 2.048 referred for MPI from a cardiology...

10.4274/mirt.galenos.2020.88261 article EN Molecular Imaging and Radionuclide Therapy 2020-10-01

Background Thrombolysis in Myocardial Infarction Frame Count (TFC) is an index that provides a quantitative evaluation of coronary microvascular dysfunction. In this study, we aimed to examine the effect COVID-19 infection on TFC patients admitted with chest pain and dyspnoea after disease had abnormal findings myocardial perfusion scintigraphy.Methods For single-center retrospective without history who were underwent angiography for scintigraphy between January 1, 2021 June 30, analysed....

10.1080/00015385.2022.2067641 article EN Acta Cardiologica 2022-04-22

The objectives of this prospective study are to compare intravenous contrast-enhanced (CE) fluorine-18-fluorodeoxyglucose (F-FDG) PET/computed tomography (CE F-FDG PET/CT) with conventional methods (CT/MRI) and evaluate the relationship maximum standardized uptake value (SUVmax) Fuhrman grade in patients renal tumors.A total 62 [35 males 27 females; mean age 55.8±12.7 (range: 27-81) years] were enrolled study. CE PET/CT scanning included whole-body (early) abdominal imaging (late) 1 2 h...

10.1097/mnm.0000000000000915 article EN Nuclear Medicine Communications 2018-09-26

Abstract A 77-year-old man with newly diagnosed prostate adenocarcinoma a total - specific antigen level of 6.4 ng/mL and Gleason score 7 (4 + 3) was referred to 68 Ga–prostate-specific membrane antigen-11 (PSMA) PET/CT for initial staging. An intense focal PSMA uptake shown in the right peripheral zone gland consistent primary tumor. Additionally, demonstrated PSMA-avid soft tissue mass left cerebellopontine angle. The patient had history left-sided sensorineural hearing loss.

10.1097/rlu.0000000000002716 article EN Clinical Nuclear Medicine 2019-07-15

Abstract A 56-year-old woman presented with abdominal pain and vomiting. Her CT revealed an retroperitoneal mass in the left upper quadrant of abdomen. 18 F-FDG PET/CT performed for metabolic characterization showed low to moderate heterogenous FDG uptake. 68 Ga–fibroblast activation protein-specific inhibitor (FAPI)–04 according a research carried out our department high radiopharmaceutical The patient was diagnosed leiomyosarcoma after R0 tumor resection. This case that Ga-FAPI-04 could be...

10.1097/rlu.0000000000003673 article EN Clinical Nuclear Medicine 2021-05-03

We present the case of a 75-year-old man with osteosarcoma sternum in whom 68Ga-prostate-specific membrane antigen (PSMA) PET/CT showed high radiotracer activity primary tumor and metastatic lesions than 18F-FDG PET/CT. The shows that 68Ga-PSMA is very useful for staging due to vivo expression PSMA. can have potential effects on prognosis response assessment following treatment osteosarcoma. use PSMA-targeted radioligand treatments may be beneficial especially chemorefractory

10.1097/rlu.0000000000003320 article EN Clinical Nuclear Medicine 2020-10-08
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