A5006529816- Peptidase Inhibition and Analysis
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Protease and Inhibitor Mechanisms
- Cardiac Structural Anomalies and Repair
- Radiopharmaceutical Chemistry and Applications
- Hepatocellular Carcinoma Treatment and Prognosis
- Prostate Cancer Treatment and Research
- Liver Disease Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Medical Imaging and Pathology Studies
- Occupational and environmental lung diseases
- Prostate Cancer Diagnosis and Treatment
- Breast Cancer Treatment Studies
- Head and Neck Cancer Studies
- Pleural and Pulmonary Diseases
- Neuropeptides and Animal Physiology
- Salivary Gland Disorders and Functions
- Salivary Gland Tumors Diagnosis and Treatment
- Thyroid Cancer Diagnosis and Treatment
- Ubiquitin and proteasome pathways
- Nanoplatforms for cancer theranostics
- Cancer Risks and Factors
- Vascular Tumors and Angiosarcomas
- Laser Applications in Dentistry and Medicine
Diyarbakır Gazi Yaşargil Eğitim ve Araştırma Hastanesi
2021-2025
Sağlık Bilimleri Üniversitesi
2021-2025
GTx (United States)
2025
University of Health Sciences
2021-2024
University of Health Science
2023-2024
Dicle University
2019-2021
Objective In this study, we aimed to evaluate the diagnostic sensitivities of 68 Ga-FAPI-04 PET/CT and 18 F-FDG in primary tumor, nodal, peritoneal distant organ metastases recurrent gastric adenocarcinoma (GAc) with patient lesion-based comparison. Materials method Twenty-one patients histopathologically proven newly diagnosed or GAc who underwent imaging were included study. Both techniques evaluated visually according intensity organ-based uptake. SUVmax tumor-to-background ratio (TBR)...
The prevalence of metastatic colorectal cancer (mCRC) is increasing and linked to poor overall survival (OS). Previous studies have aimed determine the predictive value scores laboratory tests for OS in mCRC patients, but their findings been inconclusive. In this research, we focused on determining prognostic significance fibrosis-4 (FIB-4) index, aspartate aminotransferase (AST) platelet (PLT) ratio index (APRI), albumin-bilirubin (ALBI) score, gamma-glutamyl transpeptidase PLT (GPR) with...
Objective This study aimed to determine the contribution of tubarial salivary glands total gland function using quantitative parameters obtained from 68 Ga-prostate-specific membrane antigen (PSMA) PET/computed tomography (PET/CT), including volume (SV) and (SF). Method retrospectively designed included 102 patients with prostate cancer (PCa) who had undergone Ga-PSMA PET/CT for staging purposes between January 2022 December 2023. Patients missing data, those tumors in head neck region,...
68Ga-fibroblast activation protein-specific inhibitor (FAPI)-04 PET/CT was performed in a 49-year-old woman diagnosed with breast cancer. In imaging, intense 68Ga-FAPI uptake observed the primary tumor, axillary lymph nodes, and also thyroid gland, whereas pathological 18F-FDG not gland. On ultrasonography, parenchyma heterogeneous, an area of focal thyroiditis superior part right lobe. Biochemical parameters were found to be consistent thyroiditis. This case shows that FAPI gland may...
In this study, we aimed to compare the diagnostic accuracy of 18 F-fluorodeoxyglucose ( F-FDG) and Gallium-68 labeled fibroblast activator protein inhibitor 68 Ga-FAPI)-04 PET/CT in tumor-node-metastasis (TNM) staging patients with nonsmall cell lung cancer (NSCLC) investigate whether adenocarcinoma (ADC) squamous (SCC) exhibit different uptake patterns on Ga-FAPI-04 PET/CT.Twenty-nine a histopathologically-confirmed diagnosis NSCLC, who had no history previous radiation therapy or...
Objective. The aim of this study is to investigate the uptake 68Ga-FAPI-04 in normal tissues and calculate standardized values (SUVs) for various organs body. Methods. A total 49 patients who underwent PET/CT were included our study. following identified on CT images: brain, parotid, submandibular glands, palatine tonsils, thyroid, lymph nodes (if present), breasts, lungs, thymus, left ventricle walls, mediastinal blood pool, vertebral bone marrow, liver, spleen, pancreas, stomach, small...
18 F-FDG PET/CT imaging was performed for restaging in a 16-year-old boy who operated on right testicular tumor and diagnosed with malignant mixed germ cell tumor. Mild FDG uptake observed 2 nodules both lungs retroperitoneal lymph node the abdomen. 68 Ga-FAPI (fibroblast activation protein inhibitor) 04 showed moderate of FAPI lung node. In this case, Ga-FAPI-04 shown to be superior evaluation metastases.
Abstract 18 F-FDG PET/CT was performed to evaluate the response treatment in a 62-year-old female patient who operated for adrenocortical carcinoma. High FDG uptake observed recurrent lesion left adrenal gland site and metastatic lesions. In 68 Ga-FAPI-04 study, low FAPI both recurrences metastases. this case, we demonstrated superiority of over evaluation
Abstract An 83-year-old man presented with abdominal pain, vomiting, and bloating. His CT revealed heterogeneous peritoneal thickening in the lower quadrants, which was more prominent pelvic region. 18 F-FDG PET/CT performed to locate primary tumor showed irregular omental low moderate FDG uptake. 68 Ga–FAPI (fibroblast activation protein–specific inhibitor)–04 of patient, whose could not be detected using FDG, high radiopharmaceutical uptake areas on serosal surfaces. Peritoneal Tru-Cut...
This study was conducted to compare the diagnostic accuracy of gallium-68-radiolabeled fibroblast activation protein inhibitor (68Ga-FAPI-04), positron emission tomography/computed tomography (PET/CT), and fluorine-18-fluorodeoxyglucose (18F-FDG) PET/CT based on peritoneal carcinomatosis (PC) index for detecting metastases various cancer types, evaluate potential benefits FAPI in patients with metastases.This retrospective included 57 between November 2020 December 2021. All underwent...
In this study, we aimed to compare the role of 68 Ga-labeled FAP inhibitor ( Ga-FAPI)-04 PET/computed tomography (CT) and 18 F-fluorodeoxyglucose F-FDG) PET/CT in evaluation primary tumor metastases patients diagnosed with malignant mesothelioma.Our prospective study included 21 histopathological diagnosis mesothelioma who underwent both Ga-FAPI-04 F-FDG imaging between April 2022 September 2022. Maximum standardized uptake value (SUVmax), metabolic volume, total lesion glycolysis,...
A patient with left upper quadrant breast cancer who had 18F-FDG PET/CT imaging underwent 68Ga-Trivehexin PET/CT. showed higher radiotracer accumulation in the primary tumor, internal mammary lymph nodes, and axillary nodes compared However, Trivehexin uptake was not observed FDG-positive mediastinum hilar region. Benign cytological findings were noted biopsy of subcarinal node. This case demonstrates that use suspicious areas difficult to cases can contribute accurate staging.
We compared the diagnostic accuracies of 68Ga FAPI-04 PET/CT and 18F-FDG for detecting liver metastases (LMs) in patients with different cancer types.This retrospective study included 63 lesions who underwent 68Ga-FAPI-04 between May 2020 2022. Patients histopathologically confirmed primary diagnoses, data that could be accessed retrospectively, by biopsy over at least 3-6 months follow-up (via ultrasonography, CT, magnetic resonance imaging, PET/CT, or laboratory tests) were included....
A soft tissue lesion surrounding the left kidney was detected in 18F-FDG PET/CT performed with suspicion of recurrence a patient who operated for descending colon cancer and showed mild FDG uptake. Intense fibroblast activation protein-specific inhibitor (FAPI) uptake perirenal observed 68Ga-FAPI-04 PET/CT. Tru-cut biopsy revealed signet ring cell carcinoma metastasis. This case demonstrated that could be promising radiopharmaceutical evaluation carcinomas.
18F-FDG PET/CT performed for staging of colon cancer in a 60-year-old woman revealed thymic neoplasm with increased radiopharmaceutical uptake the anterior mediastinum. 68Ga-FAPI showed low FAPI mediastinal mass. The patient was diagnosed type B3 thymoma by histopathologic evaluation. In this case, demonstrated lower than FDG. Larger studies are required differentiation malignant and benign masses FAPI.
SUMMARY OBJECTIVE: This study aimed to determine the thoracic and extra-thoracic extension of disease in patients diagnosed with lung cancer who had whole-body F18-fluorodeoxyglucose positron emission tomography/CT imaging investigate whether there is a relationship between tumor size extrathoracic spread. METHODS: A total 308 were included this study. These first classified as group 1 (SPN 30 mm>longest lesion diameter ≥10 mm) 2 (lung mass (longest ≥30 mm), then same 3 (nodular ≤20 4 >20...
A 32-year-old man with epithelioid hemangioendothelioma was imaged 68 Ga-PSMA PET/CT to evaluate the potential of 177 Lu-PSMA radionuclide therapy after progression findings were observed on follow-up 18 F-FDG imaging. Liver lesions showed low FDG SUV max . The lesion-to-background ratio (TBR) calculated as 5.1/2.9 However, moderate PSMA TBR 4.5/1.1. In conclusion, in this case report, we demonstrated that may be promising for therapy.
Purpose The present study aimed to predict the prognostic role of quantitative 18 F-fluorodeoxyglucose PET/computed tomography parameters such as maximum standardized uptake value (SUV max ), metabolic tumor volume (MTV), and total lesion glycolysis (TLG) obtained from primary tumor, lymph node metastases, liver metastasis (LM) in patients with colorectal LM (CLM). Material method research was designed a retrospective 66 CLM were enrolled between January 2017 December 2018. Primary SUV (PSUV...
<title>Abstract</title> <bold>Background:</bold> The prevalence of metastatic colorectal cancer (mCRC) is increasing and linked to poor overall survival (OS). Previous studies have aimed determine the predictive value scores laboratory tests for OS in mCRC patients, but their findings been inconclusive. In this research, we focused on determining prognostic significance fibrosis-4 (FIB-4) index, aspartate aminotransferase (AST) platelet (PLT) ratio index (APRI), albumin–bilirubin (ALBI)...