A5089582099- Additive Manufacturing and 3D Printing Technologies
- 3D Printing in Biomedical Research
- Tracheal and airway disorders
- Photopolymerization techniques and applications
- Advanced Sensor and Energy Harvesting Materials
- Innovations in Concrete and Construction Materials
- Head and Neck Surgical Oncology
- Electrospun Nanofibers in Biomedical Applications
- Drug Solubulity and Delivery Systems
- Bone Tissue Engineering Materials
- Advanced Drug Delivery Systems
- RNA Interference and Gene Delivery
- Advanced Polymer Synthesis and Characterization
- MXene and MAX Phase Materials
- Airway Management and Intubation Techniques
- Biochemical and Structural Characterization
- Polymer composites and self-healing
- Economic and Technological Systems Analysis
- Nanoplatforms for cancer theranostics
- Cell Image Analysis Techniques
- Vascular Anomalies and Treatments
ETH Zurich
2020-2025
Abstract Since the first report of 3D printed biodegradable structures by stereolithography, vat photopolymerization has shown great potential in fabrication medical implants and devices. Despite its superior printing quality manufacturing speed, development devices this technique remains challenging. This results from conflicting viscosity requirements for resins, i.e., low is required high‐resolution printing, whereas high often needed to provide mechanical strength. Recently emerging...
Customized bioresorbable airway stents with elasticity similar to silicone were 3D printed by digital light processing.
Digital light processing (DLP) 3D printing is a promising technique for the rapid manufacturing of customized medical devices with high precision. To be successfully translated to clinical setting, challenges in development suitable photopolymerizable materials have yet overcome. Besides biocompatibility, it often desirable printed biodegradable, elastic, and therapeutic function. Here, multifunctional DLP material system based on composite gold nanorods polyester copolymer reported. The...
Abstract Digital light processing (DLP) of structurally complex poly(ethylene glycol) (PEG) hydrogels with high mechanical toughness represents a long‐standing challenge in the field 3D printing. Here, we report printing approach for high‐resolution manufacturing and mechanically strong PEG via heat‐assisted DLP. Instead using aqueous solutions photo‐crosslinkable monomers, macromonomer melts were first printed absence water, resulting bulk networks. Then, post‐printing swelling networks was...
Peptides represent a rapidly expanding class of drugs with broad therapeutic potential. However, due to their large molecular weight and susceptibility degradation in the gastrointestinal tract, most peptide are administered via subcutaneous (SC) injections. Despite extensive research, painless delivery platform for these is still lacking. Recently, an octopus-inspired buccal patch has shown promise addressing this challenge by leveraging synergistic combination mechanical stretching...
Vat photopolymerization 3D printing provides new opportunities for the fabrication of tissue scaffolds and medical devices. However, manufacturing biodegradable elastomers, it usually requires use organic solvents to dissolve solid photoinitators achieve low resin viscosity, making this process environmentally unfriendly not optimal biomedical applications. Here, we report solvent-free elastomers by digital light processing with well-defined photoinitiator–polymer conjugates. Being in liquid...
3D printing is a powerful manufacturing technology for shaping materials into complex structures. While the palette of printable continues to expand, rheological and chemical requisites are not always easy fulfill. Here, universal platform reported intricate geometries without need their printability, but instead using light-based printed salt structures as leachable molds. The photocurable resins loaded with NaCl particles. printing, debinding, sintering steps involved in process...
Digital light 3D printing of biodegradable elastomers with mechanical properties comparable to the ones Sylgard-184 via dual-polymer resins.
To date, several types of airway stents are available to treat central obstructions. However, the ideal stent that can overcome anatomical, mechanical and microbiological issues is still awaited. In addition, therapeutic effect self-elimination these desirable properties, which pose an additional challenge for development manufacturing. We aimed create a prototype bioresorbable tracheal with acceptable clinical tolerance, fit biocompatibility, could be tested in rabbit model future further...
Digital light processing (DLP) of poly(ethylene glycol) (PEG) hydrogels with high mechanical toughness represents a long-standing challenge in the 3D printing field. Here, we report approach for high-resolution manufacturing structurally complex and mechanically strong PEG via heat-assisted DLP. Instead using aqueous solutions photocrosslinkable monomers, macromonomer melts were first printed absence water, resulting bulk networks. Then, post-printing swelling networks was achieved producing...
Airway stents are life-saving medical devices used to treat malignant or benign central airway stenoses. Unfortunately, these devices, typically manufactured from silicone alone and/or nitinol, can result in serious complications, such as stent migration, bacterial colonization, and tissue granulation, eventually forcing removal. Customized exhibit reduced migration they be tailored address other complications by releasing drugs, the antibiotic levofloxacin antifibrotic drug nintedanib....
Abstract Central airway obstruction is a life-threatening disorder causing high physical and psychological burden to patients due severe breathlessness impaired quality of life. Standard-of-care stents are silicone tubes, which cause immediate relief, but prone migration, especially in growing patients, require additional surgeries be removed, may further tissue damage. Customized with tailorable bioresorbability that can produced reasonable time frame would highly needed the management this...
Photopolymerization-based 3D printing is now a well-established manufacturing technique for wide range of applications, as it allows the customized fabrication objects with high resolution, tunable mechanical properties, and various functionalities. However, after printing, crosslinked polymeric networks cannot be easily degraded recycled, raising economic environmental concerns. To date, only few reprocessable or partially recyclable resins have been reported. These are based on complex...
3D Printing In article number 2203878, Kunal Masania, André R. Studart, and co-workers present a light 3D-printable salt ink as sacrificial template for the shaping of complex materials. This offers unprecedented freedom to hard-to-print materials such magnesium resorbable bone implants, or polystyrene polycaprolactone cell culture scaffolds.