- Advanced Radiotherapy Techniques
- Endometrial and Cervical Cancer Treatments
- Breast Cancer Treatment Studies
- Lung Cancer Diagnosis and Treatment
- Head and Neck Cancer Studies
- Cancer Diagnosis and Treatment
- Effects of Radiation Exposure
- Management of metastatic bone disease
- Brain Metastases and Treatment
- Cervical Cancer and HPV Research
- Nonmelanoma Skin Cancer Studies
- Advances in Oncology and Radiotherapy
- Cancer Treatment and Pharmacology
- Lung Cancer Treatments and Mutations
- Head and Neck Surgical Oncology
- Colorectal Cancer Screening and Detection
- Cutaneous Melanoma Detection and Management
- Glioma Diagnosis and Treatment
- Ovarian cancer diagnosis and treatment
- Lung Cancer Research Studies
- Sarcoma Diagnosis and Treatment
- Genital Health and Disease
- Global Cancer Incidence and Screening
- Multiple Myeloma Research and Treatments
- Radiation Therapy and Dosimetry
Ege University
2012-2023
Ege Üniversitesi Tıp Fakültesi Hastanesi
1995-2019
Marmara University
2009
Istanbul University
2009
Ankara University
2009
Pamukkale University
2006
Abstract To identify the outcomes of prognostic factors solitary plasmacytoma mainly treated with local radiotherapy (RT). The data were collected from 80 patients (SP). Forty (50.0%) received (RT) alone while 38 them (47.5%) surgery (S) and RT. median radiation dose was 46 Gy (range 30–64). follow up 2.41 years 0.33–12.33). Ten‐year overall survival (OS) relapse‐free (LRFS) 73% 94%, respectively. progression‐free (PFS) multiple myeloma‐free (MMFS) 3.5 4.8 years, On multivariate analyses,...
Evaluating the effect of hormonal treatment on quality life (QoL) in breast cancer patients by using Functional Assessment Cancer Treatment (FACT) questionnaire is main purpose this trial.Breast treated with adjuvant between January 2007 and December 2009 were evaluated. The first survey was done after completed their whole except for therapy as 'basal assessment.' second 6 to 12 months basal surveys during routine policlinic controls. last within 18 24 follow-up period.The marital status,...
PI3K/Akt/mTOR pathway activation causes relapse and resistance after radiotherapy in breast cancer (BC). We aimed to radiosensitize BC cell lines irradiation (IR) by PKI-402, a dual PI3K/mTOR inhibitor.We performed cytotoxicity, clonogenicity, hanging drop, apoptosis double-strand break detection, phosphorylation of 16 essential proteins involved the pathway.Our findings showed that PKI-402 has cytotoxic efficiency all lines. Clonogenic assay results plus IR inhibited colony formation...
In recent years, immunotherapy has become an important treatment alternative in the of many cancers.Research on prostate cancer been accelerated by obtaining Food and Drug Administration (FDA) approval sipuleucel-T for asymptomatic or minimal symptomatic metastatic castration-resistant (CRPC).Despite all these developments, patients whom agents should be used, sequential use combination strategies remain unclear.In this review, mechanisms action survival outcomes different immunotherapeutic...
Triple negative breast cancer (TNBC) is generally considered as a poorer prognostic subgroup, with propensity for earlier relapse and visceral involvement. The aim of this study to evaluate the outcome non-metastatic TNBC patients from different centers in Turkey identify clinical pathologic variables that may effect survival.Between 1993-2007, five Turkey, 316 nonmetastatic triple were identified follow-up at least 12 months. data was collected retrospectively patient charts. impact several...
Objective: This study aimed to minimize the radiation dose organs other than target tissue during adjuvant therapy applied for breast cancer, by using different planning methods.Materials and Methods: 30 women with T1-2 N1-3 M0 cancer were included in study.Planning was performed four methods supraclavicular area, internal, external tangential fields.All done a virtual environment requested data obtained.All patients treated 1st method.Method 1: Different isocenter, complete half beam.Method...
Objective: Quality-of-Life (QoL) has an important role for breast cancer patients when considering long life expectancy. The main purpose of this study is evaluating the impact hormonal therapy upon QoL, which applied after radiotherapy, in light realistic data. Materials and Methods: treated with adjuvant radiotherapy at Ege University Hospital between January 2007 December 2009 were evaluated trial obtaining their informed consent FACT-Gv4 FACT-ESv4 FACT-ES questionnaires used QoL...