- Mesenchymal stem cell research
- Periodontal Regeneration and Treatments
- Osteoarthritis Treatment and Mechanisms
- Wound Healing and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Tissue Engineering and Regenerative Medicine
- Bone Tissue Engineering Materials
- Mobile Health and mHealth Applications
- Health Literacy and Information Accessibility
- Bone and Joint Diseases
- MicroRNA in disease regulation
- Sports injuries and prevention
- Vaccine Coverage and Hesitancy
- Medical Research and Treatments
- Pressure Ulcer Prevention and Management
- Lower Extremity Biomechanics and Pathologies
- Cancer, Lipids, and Metabolism
- Dental Implant Techniques and Outcomes
- Pancreatic and Hepatic Oncology Research
- Cancer Immunotherapy and Biomarkers
- Knee injuries and reconstruction techniques
- Diabetic Foot Ulcer Assessment and Management
- Surgical Sutures and Adhesives
- Cardiovascular Health and Risk Factors
- Total Knee Arthroplasty Outcomes
Pham Ngoc Thach Hospital
2014-2022
Taipei Medical University
2018-2022
Trường ĐH Nguyễn Tất Thành
2022
University of Freiburg
2019
Khanh Hoa General Hospital
2018
New Jersey Institute of Technology
2003-2004
Abstract Osteoarthritis (OA) is a degenerative cartilage disease that characterized by local inflammatory reaction. Consequently, many studies have been performed to identify suitable prevention and treatment interventions. In recent years, both arthroscopic microfracture (AM) stem cell therapy used clinically treat OA. This study aimed evaluate the clinical effects of AM in presence absence stromal vascular fraction (SVF) injection management patients with Thirty grade 2 or 3 (Lawrence...
The development of non-cellularized composites chitosan (CHI) hydrogels, filled with cellulose nanofibers (CNFs) the type nanofibrillated cellulose, was proposed for repair and regeneration intervertebral disc (IVD) annulus fibrosus (AF) tissue. With achievement CNF-filled CHI biomaterial-based implants were designed to restore damaged/degenerated discs. structural, mechanical biological properties developed hydrogel investigated. neutralization weakly acidic aqueous CNF/CHI viscous...
Abstract In this study, the wound healing properties of gelatin‐based hydrogel (GBH) dressing combined with adipose‐derived stem cells (ADSCs) were investigated using mouse and porcine models. The analytical results showed that ADSCs harvested from significantly increased cell growth promoted differentiation (adipogenesis osteogenesis) in comparison to vitro . Moreover, vivo also indicated GBH its culture medium could potentially accelerate presented a possibility recovery wounds injuries...
Background: Health literacy (HL) is an important factor in improving health inequalities poor and marginalized groups. Assessing comprehensive HL critical. In this study, we validated the use of a short-form survey tool (HLS-SF12) examined determinants among people rural areas. Methods: A cross-sectional study was conducted July 2019 on 440 residing mountainous areas Vietnam. measured using HLS-SF12. Personal characteristics were also collected. We analyzed data confirmatory analysis,...
Knee osteoarthritis (OA) is one of the most prevalent disorders in elderly population. Among various therapeutic alternatives, we employed stromal vascular fraction (SVF), a heterogeneous cell population, to regenerate damaged knee cartilage. OA patients were classified on basis age, gender, body mass index (BMI), and x-ray-derived Kellgren-Lawrence (KL) grade. They treated with SVF followed-up for 24 months. Visual analogue scale (VAS) Western Ontario McMaster Universities Osteoarthritis...
Osteoarthritis (OA) poses a major clinical challenges owing to limited regenerative ability of diseased or traumatized chondrocytes in articular cartilage.Previous studies have determined the individual therapeutic efficacies hyaluronic acid (HA) and platelet-rich plasma (PRP) on OA; however, underlying mechanism is still lacking.Therefore, we investigated mechanistic approach HA+PRP therapy chondrocyte apoptosis IL-1β+TNF-α (I+T) treated vitro OA model, addition vivo anterior cruciate...
Diabetic foot ulcer is a major complication of diabetes mellitus. It occurred in about 15% all diabetic patients. To date, the outcome management poor and low sufficient. Some new therapies were suggested to manage treat this disease. In almost therapies, relates debridement wound, revascularization, off-loading ulcer, antibacterial actions, stimulating granulation, epidermization angiogenesis. This study aimed evaluate effects activated platelet rich plasma (aPRP) on healing volunteer There...
Background Hypertension is a major cause of death and disability worldwide. Enhancing health literacy (HL) may help to alleviate the risk hypertension its burden. However, evidence on association between HL potential mechanisms remain be explored. Objectives This study examined hypertension; explored whether body mass index (BMI), fat percentage (PBF), visceral (VF) were mediators this in people who resided rural suburban areas Vietnam. Methods A cross-sectional survey was conducted from 1st...
In comparison with the single-bundle technique, double-bundle anterior cruciate ligament (ACL) reconstruction has proven its superiority regarding biomechanical studies and clinical outcomes in both rotational knee stability translation function. However, complexity risk of complications remain a great concern for orthopaedic surgeon performing ACL reconstruction. We present simplified by 3-inside technique 2 suspension buttons 1 interference screw. The semitendinosus tendon is tripled to be...
Bone marrow mesenchymal stem cells (BM-MSCs) are multipotent that can differentiate into some kinds of such as osteoblasts, chondroblasts and adipocytes. These were discovered for a long time considered the first source MSCs. BM-MSC transplantation was used to treat diseases bone disease, myocardial infarction, stroke, diabetes mellitus… This study aimed provide new method in vitro primarily culture secondary BM-MSCs compliant with good manufacturing practice clinical applications....
Mesenchymal Stem Cell Therapy (MSC) is one of the newest and most advanced therapies in Regenerative Integrative Medicine for a variety medical problems that are not easily treated with traditional conventional allopathic approaches. There an abundance clinical experience by numerous physicians, patients researchers proving consistently mesenchymal stem cell-MSC therapy can be extremely helpful Osteoarthritis Rheumatoid Arthritis. In Viet Nam we have several researches cells application OA
For bone tissue regeneration utilizing mesenchymal stem cells, it is important to use a scaffold that supports differentiation yet be fully degradable over time so as promote full repair and remodeling of the defect. This study investigated osteogenic human MSCs on varying ratios hydroxyapatite/tricalcium phosphate (HA/TCP) ceramic scaffolds. The faster degrading ratio 20% HA/80% TCP was compared with slower/nonresorbable formulation 60/40 ceramic. were grown these ceramics in presence or...