A5008323022- Asymmetric Hydrogenation and Catalysis
- Catalytic C–H Functionalization Methods
- Radical Photochemical Reactions
- Organometallic Complex Synthesis and Catalysis
- Sulfur-Based Synthesis Techniques
- Catalytic Cross-Coupling Reactions
- Chemical Synthesis and Analysis
- Asymmetric Synthesis and Catalysis
- Carbon dioxide utilization in catalysis
- Advanced Synthetic Organic Chemistry
- Nanoplatforms for cancer theranostics
- Synthesis and pharmacology of benzodiazepine derivatives
- bioluminescence and chemiluminescence research
- Fluorine in Organic Chemistry
- Synthesis and Biological Evaluation
- Synthetic Organic Chemistry Methods
- Luminescence and Fluorescent Materials
- Molecular spectroscopy and chirality
- Axial and Atropisomeric Chirality Synthesis
- Synthesis and Catalytic Reactions
- Surface Chemistry and Catalysis
- Microwave-Assisted Synthesis and Applications
- Oxidative Organic Chemistry Reactions
- Chemical Synthesis and Characterization
- Coordination Chemistry and Organometallics
Zhengzhou University
2014-2023
Anhui Normal University
2018-2022
Southern University of Science and Technology
2020
University of Arizona
2019
Ministry of Education of the People's Republic of China
2018
American Petroleum Institute
2008
Northeast Petroleum University
2007
An approach for efficient synthesis of C-glycosyl amino acids is described. Different from typical photoredox-catalyzed reactions imines, the new process follows a pathway in which α-imino esters serve as electrophiles chemoselective addition with nucleophilic glycosyl radicals. The highlighted by mild nature reaction conditions, highly stereoselectivity attending C–C bond formation, and its applicability to C-glycosylations using both armed disarmed pentose hexose derivatives.
Abstract The development of enantioselective alkyl–alkyl cross‐couplings with coinstantaneous formation a stereogenic center without the use sensitive organometallic species is attractive yet challenging. Herein, we report intermolecular regio‐ and formal hydrofunctionalizations acrylamides, forging α‐position to newly formed C sp3 –C bond for first time. developed chiral ligand enables electronically‐reversed hydrofunctionalizations, including hydroalkylation, hydrobenzylation,...
The first piezochemically driven decarboxylative coupling of the C–H bond was developed. agitation BaTiO3 via ball milling converts mechanical energy into electrical potential, leading to production a benzoyl radical single-electron transfer pathway analogous photocatalytic reaction. This mechanoredox catalytic strategy synthesize C3-acylated quinoxalin-2(1H)-ones requires no solvent, short reaction time, and simple handling skills, exhibiting promising potential in large-scale chemical...
Abstract A metal‐ and oxidant‐free catalytic method for accessing structurally diverse thioesters from readily accessible, widespread aldehydes, is described. strategy of a simple organic 9,10‐phenanthrenequinone‐promoted hydrogen atom transfer (HAT) with visible light was successfully implemented to selectively generate acyl radicals without inducing crossover reactivity thioester products. The preparative power the demonstrated by broad substrate scope wide functional group tolerance,...
Abstract The development of enantioselective alkyl–alkyl cross‐couplings with coinstantaneous formation a stereogenic center without the use sensitive organometallic species is attractive yet challenging. Herein, we report intermolecular regio‐ and formal hydrofunctionalizations acrylamides, forging α‐position to newly formed C sp3 –C bond for first time. developed chiral ligand enables electronically‐reversed hydrofunctionalizations, including hydroalkylation, hydrobenzylation,...
TXPhos, a highly stable and efficient ligand designed for ppm level Pd catalyzed Suzuki–Miyaura coupling reactions under micellar conditions with TOF up to 40 000 s −1 .
Abstract An cascade intramolecular 5‐ exo‐dig cyclization of N ‐(2‐iodophenyl)propiolamides and sequential amination/etherification (with ‐hydroxybenzamides, phenyl hydroxycarbamate) protocol for the synthesis amino‐ phenoxy‐substituted 3‐methyleneindolinones using unexpensive Pd(PPh 3 ) 4 as catalyst has been developed. The enables assembly structurally important oxindole cores featuring moderate functional group tolerance (particularly halo group), affording a broad spectrum products with...
Abstract A cascade C−H activation, annulation, and etherification of N ‐hydroxybenzamides with propargylamines provides a flexible route to ‐alkoxylated 3‐arylisoindolin‐1‐ones. Three new bonds (C−C, C−N, C−O) are generated afford series isoindolin‐1‐ones bearing tetrasubstituted carbon in 49–82% yield. The utility this method was showcased by gram‐scale synthesis synthetic transformations the product access structurally diverse isoindolinones. magnified image
Two novel quinoxaline-bridged bisBODIPYs have been synthesized by the condensation of 2,3-bis(5-formylpyrrol-2-yl)quinoxaline with 3-ethyl-2,4-dimethylpyrrole followed a modification using Knoevenagel reaction. They were well characterized X-ray diffraction, NMR, HRMS UV-vis and fluorescence spectroscopy. These two unusual broad absorption bands, which are different from those typical BODIPYs exhibit red-shifted emission bands centered at around 610 nm 730 respectively larger Stokes shifts...
A new asymmetric activation strategy for hydrazones as acyl anion equivalents in the dinuclear zinc cooperative catalyzed carbonyl-ene reaction was developed.
A B S T R C TThe scope limitation of substrates especially for five-member heteroaryl often presenting in medical and bioactive molecules, along with high palladium loadings sometimes needing strong bases, perplexes the application palladium-catalyzed C-N cross-coupling reactions. The terphenyl phosphine TXPhos supported catalyst [(TXPhos)(allyl)PdCl] dramatically broadened existing five-membered made weak bases KHCO3 KOAc become general optimal choices. Therefore, barrier has been broken an...