A5079303434- Psychopathy, Forensic Psychiatry, Sexual Offending
- Suicide and Self-Harm Studies
- Child and Adolescent Psychosocial and Emotional Development
- Schizophrenia research and treatment
- Child Abuse and Trauma
- Organ Transplantation Techniques and Outcomes
- Attention Deficit Hyperactivity Disorder
- Ferroptosis and cancer prognosis
- Radioactive element chemistry and processing
- Maritime Ports and Logistics
- Criminal Justice and Corrections Analysis
- RNA modifications and cancer
- Crop Yield and Soil Fertility
- Heavy Metal Exposure and Toxicity
- Liver Disease and Transplantation
- Dysphagia Assessment and Management
- Nuclear Materials and Properties
- Cancer, Lipids, and Metabolism
- Gout, Hyperuricemia, Uric Acid
- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Sleep and related disorders
- Nerve injury and regeneration
- Healthcare Decision-Making and Restraints
- Pancreatic and Hepatic Oncology Research
Shenzhen KangNing Hospital
2018-2025
Jinzhou Kangning Hospital
2018-2025
First Affiliated Hospital of Xi'an Jiaotong University
2018-2024
Second Affiliated Hospital of Zhejiang University
2024
Yunnan University of Traditional Chinese Medicine
2022-2024
Zhejiang University
2022-2023
Xi'an Polytechnic University
2023
Institute of High Energy Physics
2021-2023
East China University of Technology
2021-2023
Chinese Academy of Sciences
2021-2023
Ferroptosis is a new form of regulated cell death that mediated by intracellular iron and ester oxygenase, glutathione-dependent lipid hydroperoxidase glutathione peroxidase 4 (GPX4) prevents ferroptosis converting hydroperoxides into nontoxic alcohols. Although thiostrepton (TST) has been reported to exert antitumor effects, its role in pancreatic cancer the underlying mechanisms remain unclear. In this study, we found TST reduced viability clonogenesis lines, along with overload,...
Perineural invasion (PNI) and autophagy are two common features in the tumor microenvironment of pancreatic cancer (PanCa) have a negative effect on prognosis. Potential mediator cells molecular mechanism underlying their relationships need to be fully elucidated.To investigate Schwann (SCs) PNI, we reproduced PNI by collecting clinical tissue, performing sciatic nerve injection nude mice with establishing Dorsal root ganglion (DRG) coculture system cell lines. Autophagy was detected IHC,...
Dysphagia, or swallowing disorders, has become a growing concern due to the aging population, and health literacy plays crucial role in active aging. However, relationship between them remains unclear.To investigate association dysphagia among community-dwelling older adults China.A survey was conducted on 4462 aged 65 above community Yiwu City, China, from May 2021 January 2022. Swallowing problems were assessed using 30 ml water test (WST) Eating Assessment Tool-10 questionnaire (EAT-10)....
Perineural invasion (PNI) is an important pathologic feature of pancreatic cancer, and the incidence PNI in cancer 70%-100%. associated with poor outcome, metastasis, recurrence patients. There are very few treatments for cancer. Honokiol (HNK) a natural product that mainly obtained from Magnolia species has been indicated to have anticancer activity. HNK also potent neurotrophic activity may be effective suppressing PNI. However, potential role treatment not elucidated.In our study, cells...
Melanoma is a highly aggressive cancer that can metastasize at early stage. The aim of this study to clarify the role Piezo1 and its potential mechanism in regulating malignant phenotypes melanoma. In present study, we first showed was abnormally expressed melanoma, which accelerated progression by activating AKT/mTOR signaling. Firstly, found upregulated melanoma associated with poor survival. Additionally, knockdown significantly weakened intracellular calcium signal viability cells....
The anti-tumour effect of Huaier has been demonstrated in a variety tumours. Ferroptosis is newly identified type programmed cell death accompanied by the accumulation reactive oxygen species (ROS) and iron cells plays key role therapeutic process against malignant We aimed to explore potential pancreatic cancer uncover relationship between ferroptosis.CCK8 colony formation assays were used determine proliferation (PCs). levels cellular ROS analysed fluorescence probe, was showed Prussian...
Abstract We investigated the mental health of 232 consecutive receptions juvenile boys aged 15–17 years in youth detention centers two Chinese provinces and compared with juveniles community settings. Interviews were conducted by psychiatrists using Schedule for Affective Disorders Schizophrenia School-Age Children to diagnose DSM-IV psychiatric disorders. Of detention, 188 (81.0%) met criteria any disorder, 186 (80.2%) having a disruptive behavior disorder 52 (22.4%) substance use (SUD)....
Hydrogels are regarded as ideal tissue scaffold material due to their unique advantages, but problems such low strength and easy cracking have become bottlenecks that limit practical applicability....
People with schizophrenia (SZ) are at increased risk of violence compared to the general population. However, neural mechanisms violent behavior in patients SZ still unclear due heterogeneity diseased In this study, we aimed examine correlates and determine whether structural deficits were related psychopathic traits. A total 113 participants, including 31 (vSZ), 39 without (nvSZ), 43 healthy controls (HC), completed T1-weighted magnetic resonance imaging (MRI) scan analyzed using...