A5075814149- Acute Ischemic Stroke Management
- Neuroinflammation and Neurodegeneration Mechanisms
- Migraine and Headache Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Intracranial Aneurysms: Treatment and Complications
- Stroke Rehabilitation and Recovery
- Traumatic Brain Injury and Neurovascular Disturbances
- Stress Responses and Cortisol
- Circular RNAs in diseases
- Neurological Disease Mechanisms and Treatments
- Neuropeptides and Animal Physiology
- Bioactive natural compounds
- Neurosurgical Procedures and Complications
- Metabolism, Diabetes, and Cancer
- Mesenchymal stem cell research
- Ferroptosis and cancer prognosis
- MicroRNA in disease regulation
- Tryptophan and brain disorders
- Connective tissue disorders research
- Sympathectomy and Hyperhidrosis Treatments
- Diet and metabolism studies
- Circadian rhythm and melatonin
- Extracellular vesicles in disease
- Nerve injury and regeneration
- Inflammatory Biomarkers in Disease Prognosis
Second Affiliated Hospital of Fujian Medical University
2012-2024
Fujian Medical University
2012-2024
Background Stroke was a major global public health challenge, and its prognosis remarkably associated with inflammation levels nutritional status. The advanced lung cancer index (ALI) comprehensive indicator that combined Currently, the relationship between ALI of stroke patients not yet known. purpose current study to estimate their relationship. Methods Cohort data from National Health Nutrition Examination Survey (NHANES) 1999–2018 were collected. association all-cause cardiovascular...
Purpose: Migraine is a complex neurovascular disorder with obesity as notable risk factor. This study aimed to investigate an under-researched area of the association between migraine duration and body composition. Patients Methods: from neurology outpatient department were enrolled categorized into four groups based on illness duration: 1 year, 1– 5 years, 5– 10 > years. Patient demographics, blood biochemistry, composition data collected analyzed statistically. Results: predominantly...
Acute ischemic stroke induces systemic inflammation, exhibited as changes in body temperature, white blood cell counts and C-reactive protein (CRP) levels. The aim of the present study was to observe effects intravenous thrombolytic therapy on inflammatory indices order investigate hypothesis that post-stroke response occurs necrosis brain tissues. In this study, 62 patients with acute cerebral infarction indications for thrombolysis were divided into three groups basis their treatment...
Ischemic encephalopathy is a common clinical disease. The main treatment goal to achieve vascular recanalization. However, after recanalization, the reperfusion of fresh blood can change local cell metabolism, thus adversely affecting structure and function, which result in injury.To explore effect matrine intervention different concentrations on JAK2/STAT3 signaling pathway brain protection rats with cerebral ischemia-reperfusion.Healthy male Sprague Dawley were divided into blank control...
Objective Endovascular treatment (EVT) is, to date, the most promising of vertebrobasilar artery occlusion (VBAO). The study aimed determine influence perioperative glucose levels on clinical outcomes in patients with acute VBAO treated EVT. Methods We retrospectively collected consecutive received EVT 21 stroke centers China. associations between glycemic indicators (including fasting blood glucose[FBG], admission hyperglycemia, stress hyperglycemia ratio [SHR] and short-term variability...
Cerebral ischemia is associated with a high burden of neurological disability. Recently, emerging evidence has demonstrated that long non-coding RNAs (lncRNAs) are crucial regulators in cerebral reperfusion (I/R) injury. Herein, we investigated the function and potential mechanism intergenic non-protein coding RNA 473 (LINC00473) I/R injury.We established oxygen glucose deprivation/reperfusion (OGD/R) model Neuro-2a (N2a) cells to mimic injury vitro. RT-qPCR Western blot assays were...
<title>Abstract</title> Background Numerous observational studies have demonstrated that specific dietary factors influence aneurysmal subarachnoid hemorrhage (aSAH). However, whether a causal relationship exists between diet and aSAH remains unknown. Methods We used two-sample Mendelian randomization (MR) method to characterise the associations 26 different diets extracted from UK Biobank dataset risk. The data were obtained meta-analysis of genome-wide association International Stroke...
Acute anterior circulation large vessel occlusion refers to a blockage in the blood flow of one major vessels (front) part brain. can lead range symptoms, including sudden headache, difficulty speaking or understanding speech, weakness numbness on side body and loss vision eye. According relevant data, mechanical thrombectomy treatment recanalization rate reach 70%. However, hemorrhage is serious complications after thrombectomy, it main factor leading deterioration neurological function...
ABSTRACT Background Patients with acute vertebrobasilar artery occlusion (VBAO) after endovascular treatment (EVT) frequently require mechanical ventilation (MV). This study aims to develop and validate a predictive score for prolonged (PMV) in patients VBAO EVT. Methods The derivation cohort prospectively recruited undergoing EVT from four comprehensive stroke centers (CSCs) China. PMV was defined as continuous MV ≥96 hours. Two multivariable logistic regressions were performed predict...
Objective To investigate the clinical features of patients with multiple sclerosis (MS) and restless legs syndrome (RLS) to further examine relevant factors that may contribute co-occurrence MS RLS.Methods Seventy were recruited in present study.The RLS screen was performed based on diagnostic criteria for RLS.MS designated as case group without served control group.The data including age onset,MS duration disability by expanded status scale (EDSS) analyzed.Results There 12 total 70...