Hongxiang Chen

ORCID: 0000-0001-5801-8973
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About
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Research Areas
  • Neonatal Respiratory Health Research
  • Nutritional Studies and Diet
  • Infant Nutrition and Health
  • Alcohol Consumption and Health Effects
  • Congenital Diaphragmatic Hernia Studies
  • Vascular Malformations and Hemangiomas
  • Dermatology and Skin Diseases
  • Birth, Development, and Health
  • Cancer-related molecular mechanisms research
  • Cervical Cancer and HPV Research
  • Urticaria and Related Conditions
  • Diet, Metabolism, and Disease
  • Neuroscience of respiration and sleep
  • Genital Health and Disease
  • Hepatitis B Virus Studies
  • Laser Applications in Dentistry and Medicine
  • Supramolecular Self-Assembly in Materials
  • Eosinophilic Esophagitis
  • Congenital Heart Disease Studies
  • Ferroptosis and cancer prognosis
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Congenital gastrointestinal and neural anomalies
  • Aeolian processes and effects
  • Advanced Cellulose Research Studies
  • Polymer crystallization and properties

People's Hospital of Xinjiang Uygur Autonomous Region
2019-2025

Sichuan University
2023-2025

Wuhan University of Science and Technology
2019-2023

Meizhou City People's Hospital
2011-2022

Union Hospital
2010-2020

Huazhong University of Science and Technology
2010-2020

State Key Laboratory of Polymer Physics and Chemistry
2019

Chinese Academy of Sciences
2019

Changchun Institute of Applied Chemistry
2019

Guangdong Medical College
2008

The biological aging process can be modified through lifestyle interventions to prevent age-related diseases and extend healthspan. However, evidence from population-based studies on whether tea consumption could delay the in humans remains limited.This study included 7931 participants aged 30-79 years China Multi-Ethnic Cohort (CMEC) Study 5998 37-73 UK Biobank (UKB) who participated both baseline first follow-up surveys. Tea information was collected questionnaires. Biological age (BA)...

10.1016/j.lanwpc.2023.100955 article EN cc-by-nc-nd The Lancet Regional Health - Western Pacific 2023-11-22

Abstract Background An increasing number of extremely preterm (EP) infants have survived worldwide. However, few data been reported from China. This study was designed to investigate the short-term outcomes EP at discharge in Guangdong province. Methods A total 2051 discharged 26 neonatal intensive care units during 2008–2017 were enrolled. The 2008 2012 collected retrospectively, and 2013 2017 prospectively. Their hospitalization records reviewed. Results During 2008–2017, mean gestational...

10.1186/s12887-019-1736-8 article EN cc-by BMC Pediatrics 2019-11-04

Abstract Background and aims The relationship between alcohol consumption age‐related diseases is inconsistent. Biological age (BA) serves as both a precursor predictor of diseases; however, longitudinal associations BA in middle‐aged older people remain unclear. We measured whether there was association drinking frequency pure intake with among people. Design setting participants This study involved two prospective cohort studies, set Southwestern China the United Kingdom. A total 8046 from...

10.1111/add.16501 article EN Addiction 2024-04-28

ABSTRACT Lycopene (LYC) is an extremely powerful antioxidant with the potential to treat a range of diseases and inhibit ferroptosis. This research aims elucidate how LYC impacts polycystic ovarian syndrome (PCOS) action mechanisms. A PCOS rat model was constructed by injecting DHEA. Different doses were injected intraperitoneally in rats, estrous cycle recorded. The histopathological damage ovary rats observed HE staining, testosterone (T), estradiol (E2), luteinizing hormone (LH) follicle...

10.1002/jbt.70158 article EN Journal of Biochemical and Molecular Toxicology 2025-01-27

Little is known about the associations of changes in drinking levels with newly defined metabolic dysfunction-associated steatotic liver disease (MASLD). We therefore sought to estimate between and MASLD less developed regions China. This longitudinal study included 8727 participants from China Multi-Ethnic Cohort (CMEC) regions, all participating baseline a follow-up survey. was as hepatic steatosis, along presence at least one five cardiometabolic risks, addition limiting excessive alcohol...

10.1186/s12889-025-21752-1 article EN cc-by-nc-nd BMC Public Health 2025-02-11

Because of the unique optical properties gold nanomaterials, preparation nanomaterials with excellent chirality has received extensive attention. In order to develop a simple fabrication method for three-dimensional chiral Au nanostructures size several hundred nanometers, nanoparticles were developed transfer peptide nanoparticles. this study, controlled synthesis asymmetric nanopolyhedrons was achieved. The prepared via peptide-directed growth can exhibit strong circular dichroism (∼±50...

10.1021/acs.langmuir.9b03366 article EN Langmuir 2019-12-30

We aimed to assess the role of XPG, XPC and MMS19L polymorphisms on response chemotherapy in osteosarcomas, clinical outcomes. One hundred eighty five osteosarcoma patients who were histologically confirmed enrolled our study between January 2007 December 2009. Genotyping was performed a 384-well plate format MassARRAY® platform. Individuals with XPG TT genotype T allele more likely be better than CC genotype, OR (95% CI) 4.17 (1.64-11.54) 2.66 (1.39-5.11), respectively. Those carrying...

10.7314/apjcp.2013.14.6.3677 article EN cc-by Asian Pacific Journal of Cancer Prevention 2013-06-30

A self-powered graphene-based photodetector with high performance is particularly useful for device miniaturization and to save energy. Here, we report a graphene/silicon carbide (SiC)-based ultraviolet that exhibits current responsivity of 7.4 mA/W response frequency over megahertz under 325-nm laser irradiation. The built-in photovoltage the about four orders magnitude higher than previously reported results similar devices. These favorable properties are ascribed ingenious design using...

10.1088/1674-1056/25/6/067205 article EN Chinese Physics B 2016-06-01

Abstract With the increase in extremely low birth weight (ELBW) infants, their outcome attracted worldwide attention. However, China, related studies are rare. The hospitalized records of ELBW infants discharged from twenty-six neonatal intensive care units Guangdong Province China during 2008–2017 were analyzed. A total 2575 enrolled and overall survival rate was 55.11%. From 2008 to 2017, number increased rapidly 91 466, improved steadily 41.76% 62.02%. Increased is closely (BW), regional...

10.1038/s41598-022-14432-2 article EN cc-by Scientific Reports 2022-07-01

Abstract To investigate the associations between dietary patterns and biological aging, identify most recommended pattern for coping with aging explore potential mediating role of gut microbiota in less-developed ethnic minority regions (LEMRs). This prospective cohort study included 8288 participants aged 30-79 years from China Multi-Ethnic Cohort (CMEC). Anthropometric measurements clinical biomarkers were utilized to construct age based on Klemera Doubal’s method (KDM-BA) KDM-BA...

10.1017/s0007114524002733 article EN British Journal Of Nutrition 2024-11-04

BACKGROUND We studied the effect of APOBEC3G on persistent human papillomavirus (HPV) infection and correlation between polymorphism HPV cervical disease progression in Uygur women China. MATERIAL AND METHODS From January 2015 to December 2017, we enrolled 529 ethnic group patients with infection. SIHA cells were transfected APOBEC3G. Real-time quantitative polymerase chain reaction (RT-qPCR) Western blot analysis used detect mRNA protein expression levels E6 p53. Exon 3 was sequenced by...

10.12659/msm.916142 article EN Medical Science Monitor 2019-09-17

To investigate the longitudinal association between alcohol abstinence and accelerated biological aging among middle-aged older adults to explore potential effect modifiers influencing association.

10.12182/20240360602 article EN PubMed 2024-03-20

Topical photodynamic therapy (PDT) , a highly effective, safe and non-invasive therapeutic method, exerts good effects on various diseases in dermatology, such as actinic keratosis, condyloma acuminatum, acne, so on. The major drawback of PDT is pain during the treatment. Some patients have to interrupt or terminate treatment because intolerance. progress has been made management PDT-related pain. It revealed that multiple factors are associated with pain, including individual factors,...

10.3760/cma.j.issn.0412-4030.2016.09.024 article EN Chinese Journal of Dermatology 2016-09-15
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