- Spine and Intervertebral Disc Pathology
- Scoliosis diagnosis and treatment
- Spinal Fractures and Fixation Techniques
- Musculoskeletal pain and rehabilitation
- Cervical and Thoracic Myelopathy
- Medical Imaging and Analysis
- Spinal Hematomas and Complications
- Ergonomics and Musculoskeletal Disorders
- Occupational Health and Performance
- Muscle activation and electromyography studies
- Hip disorders and treatments
- Radiomics and Machine Learning in Medical Imaging
- Lower Extremity Biomechanics and Pathologies
- Spinal Cord Injury Research
- Drug-Induced Hepatotoxicity and Protection
- Sports Performance and Training
- Hemophilia Treatment and Research
- Nutrition and Health in Aging
- Cancer Treatment and Pharmacology
- PARP inhibition in cancer therapy
- Potassium and Related Disorders
- Colorectal Cancer Treatments and Studies
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Pleural and Pulmonary Diseases
- Frailty in Older Adults
Capital Medical University
2020-2025
National Clinical Research Center for Digestive Diseases
2020-2025
Xuan Wu Hospital of the Capital Medical University
2021
Berlin Institute of Health at Charité - Universitätsmedizin Berlin
2018-2021
Tongji University
2020-2021
Humboldt-Universität zu Berlin
2018-2020
Freie Universität Berlin
2018-2020
The Royal Melbourne Hospital
2014-2019
The University of Melbourne
2019
Shanghai East Hospital
2015-2018
Diabetes mellitus (DM) and low back pain which is mainly caused by degeneration of the intervertebral discs (IVDs) both are major public health problem worldwide. The present study was designed to investigate association between type 2 diabetes (T2D) severity lumbar disc (LDD).We retrospectively reviewed patients with visiting our spine clinic in 2014. Low all have MRI imaging no previous treatment. One hundred fifty without T2D (group A) 622 meeting criteria were included. Sex, age, body...
Lifting is generally considered as a risk factor for low back pain. A thorough investigation of the muscle function during lifting essential better assessment potential impairment and towards improvements in strategy. We aimed to compare activities trunk muscles between stoop squat tasks. surface electromyography device was used measure activity full-cycle tasks 5-kg weight. Each task divided into four stages: stage 1 bending forward reach weight, 2 weight up, 3 lowering down, 4 returning...
Monocentric, retrospective, cross-sectional study. To investigate the age-related normative values of sagittal parameters and establish their relationships in asymptomatic community-dwelling adults aged over 50. Degenerative changes spine with aging alter balance, causing pathologies. However, there was a lack comprehensive study on alignment relationship during degenerative evolution. Among total 1,370 volunteers, 701 volunteers were recruited. Participants underwent lateral X-ray, assessed...
The objective of this study is to investigate the fate albumin coupled nanoparticulate system over non-targeted drug carrier in treatment hemisectioned spinal cord injury (SCI).Targeted delivery methyl prednisolone (MP) and minocycline (MC) portrayed improved therapeutic efficacy as compared with nanoparticles (NPS).Albumin coupled, chitosan stabilized, cationic NPS (albumin-MP + MC - NPS) poly-(lactide-co-glycolic acid) were prepared using emulsion solvent evaporation method. Prepared...
To review the outcome of 32 consecutive patients who underwent 4-level anterior cervical discectomy and fusion (ACDF) with cages plates were followed up for at least 5 years.Records 19 men 13 women aged 48 to 69 years ACDF myelopathy (n=11) or myeloradiculopathy (n=21) C3 C7 by a single surgeon minimum reviewed. Clinical was assessed using visual analogue scale (VAS), Neck Disability Index (NDI), modified Japanese Orthopaedic Association (JOA) score pain myelopathic symptoms. Radiographic...
The quality of the paraspinal muscles has been recommended as a surrogate marker for evaluation severity lumbar degenerative diseases (LDD). purpose this study is to determine age- and sex-dependent differences in morphology composition between LDD asymptomatic subjects.We analyzed data from 370 patients 327 volunteers aged 18-85 years. measurement cross-sectional area (CSA) erector spinae, multifidus, psoas at L4/5-disc level was performed by magnetic resonance imaging (MRI). fatty...
Manual material handling (MMH) is considered as one of the main contributors to low back pain. While males traditionally perform MMH tasks, recently number females who undertake these physically-demanding activities also increasing. To evaluate risk mechanical injuries, majority previous studies have estimated spinal forces using different modeling approaches that mostly focus on male individuals. Notable sex-dependent differences have, however, been reported in torso muscle strength and...
The aim of the study was to evaluate role longus colli muscles in cervical vertigo. We retrospectively analyzed 116 adult patients who underwent anterior discectomy and fusion (ACDF) during 2014 our department. Patients were assigned vertigo group or nonvertigo group. Demographic data recorded. Inner distance cross-sectional area (CSA) measured using coronal magnetic resonance imaging (MRI). (n = 44) 72) similar demographic data. Mean preoperative Japanese Orthopaedic Association (JOA) score...
Objective: Preoperative tracheal retraction exercise (TRE) to minimize the occurrence of postoperative oropharyngeal dysphagia after anterior cervical spine surgery. Methods: A total 220 patients admitted for elective surgery from January 2013 December 2014 were retrospectively reviewed. The allocated into two groups: TRE group and control (without TRE). Modified scoring system (MDSS) was used evaluating presence severity symptoms at 1 week 1, 3, 6 months Demographics such as age, gender,...
Abstract Background Frailty is a condition characterized by the progressive deterioration of physiological functioning, which closely related to adverse events. Multiple previous investigations applied frailty scales for spine research, and purpose this study investigate differences in morphology paraspinal muscles frail non-frail older adults evaluated through FRAIL scale. Methods The sample retrospectively cross-sectional consisted individuals who were ≥ 60 years age with lumbar...
Based on the high prevalence and occult-onset of osteoporosis, development novel early screening tools was imminent. Therefore, this study attempted to construct a nomogram clinical prediction model for predicting osteoporosis. Asymptomatic elderly residents in training (n = 438) validation groups 146) were recruited. BMD examinations performed data collected participants. Logistic regression analyses performed. A logistic an online dynamic constructed. The validated by means ROC curves,...
As the most poorly tolerated and debilitating form of spinal malalignment, sagittal imbalance is becoming an increasingly recognized cause pain disability in adults. However, there evidence showing that has a weak or no correlation with health-related quality-of-life (HRQoL) outcomes. The objective this study was to describe direct factor associated HRQoL terms Oswestry Disability Index (ODI) assessment.This retrospectively evaluated clinical radiographic information 179 elderly patients...