- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Scoliosis diagnosis and treatment
- Musculoskeletal pain and rehabilitation
- Cervical and Thoracic Myelopathy
- Cardiac, Anesthesia and Surgical Outcomes
- Medical Imaging and Analysis
- Hip and Femur Fractures
- Pelvic and Acetabular Injuries
- Enhanced Recovery After Surgery
- Anesthesia and Pain Management
- Orthopaedic implants and arthroplasty
- Nutrition and Health in Aging
- Frailty in Older Adults
- Total Knee Arthroplasty Outcomes
- Orthopedic Infections and Treatments
- Cancer, Hypoxia, and Metabolism
- MicroRNA in disease regulation
- Bone fractures and treatments
- Spondyloarthritis Studies and Treatments
- Nerve injury and regeneration
- Stroke Rehabilitation and Recovery
- Bone and Joint Diseases
- Cardiac Ischemia and Reperfusion
- Heterotopic Ossification and Related Conditions
Capital Medical University
2016-2025
National Clinical Research Center for Digestive Diseases
2018-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
Shenyang 242 Hospital
2025
Binzhou People's Hospital
2025
Beijing Xuanwu Traditional Chinese Medicine Hospital
2020-2024
Food and Drug Administration
2024
Beihang University
2020-2023
Xuan Wu Hospital of the Capital Medical University
2020-2023
Second Affiliated Hospital of Xi'an Jiaotong University
2023
Abstract Background The clinical outcome of a new fixation device (femoral neck system, FNS) for femoral fractures remains unclear. main purpose this study was to evaluate two different internal methods the treatment in patients aged under 60 years. Methods We retrospectively studied who underwent surgery our hospital between January 2017 and 2020. Cannulated compression screws (CCS) FNS groups were divided according methods. General data (such as sex, age, body mass index, type fracture)...
A retrospective study.To evaluate the different degeneration patterns of paraspinal muscles in degenerative lumbar diseases and their correlation with spine severity. The characteristics remain unclear.78 patients diagnosed single-level spondylolisthesis (DLS) 76 kyphosis (DLK) were included as DLS DLK groups. Paraspinal muscle parameters psoas major (PS), erector spinae (ES) multifidus (MF) measured, including fatty infiltration (FI) relative cross-sectional area (rCSA), namely ratio CSA to...
To report our 11-year minimum clinical and radiological outcomes, as well complications of the Charite III total disc replacement (TDR).A 35 patients indicated for were implanted with prosthesis. Clinical evaluation included visual analog scale (VAS) back pain Oswestry disability index (ODI). Radiological parameters intervertebral height (IDH), range motion (ROM), lumbar lordosis, scoliosis prosthesis position evaluated. Complications reoperation rates also assessed.Thirty-two had a...
Abstract Background The reduction of slipped vertebra is often performed during surgery for degenerative lumbar spondylolisthesis (DLS). This approach, while potentially improving clinical and radiological outcomes, also carries a risk increased complications due to the process. To address this, we introduced an innovative lever technique DLS treatment. study aims investigate efficacy, fusion with or without reduction. Methods We conducted retrospective review prospectively collected data...
OBJECTIVE The objective of this study was to assess the complicated relationship between frailty, perioperative complications, and patient-reported outcomes (PROs) in elderly patients (≥ 75 years old) undergoing lumbar spine fusion (LSF). METHODS Consecutive who underwent LSF March 2019 December 2021 were recruited study. Frail (modified frailty index [mFI] score ≥ 2) propensity matched nonfrail (mFI 0–1) on basis age, sex, number fused levels. Perioperative complications collected assessed...
Lifting is generally considered as a risk factor for low back pain. A thorough investigation of the muscle function during lifting essential better assessment potential impairment and towards improvements in strategy. We aimed to compare activities trunk muscles between stoop squat tasks. surface electromyography device was used measure activity full-cycle tasks 5-kg weight. Each task divided into four stages: stage 1 bending forward reach weight, 2 weight up, 3 lowering down, 4 returning...
Osteoporotic vertebral compression fractures (OVCFs) can be painful. Percutaneous kyphoplasty (PKP) aims at strengthening the vertebra and reducing pain, but efficacy vary among patients. The purpose of this study was to establish a risk prediction model for pain relief following PKP in patients with OVCF. This retrospective included 208 (training set) 54 (validation OVCF who underwent bone cement treatment between January 2018 October 2023. Based on postoperative VAS scores, were divided...
The poor prognosis of adult patients with spinal deformity following long-segment fusion surgery remains a major concern. Our study aims to investigate the impact an Enhanced Recovery After Surgery (ERAS) protocol on deformity. This focused retrospective review database previous Adult who underwent from July 2016 2022 were evaluated, 2019 for pre-ERAS patient group and ERAS group. Demographic data, radiological sagittal parameters, intraoperative data collected all patients. length hospital...
Study design: A retrospective review of a prospective adult spinal deformity data. Objective: To identify distinct patient clinical profiles and recovery trajectories in patients with (ASD). Summary Background Data: Patients ASD exhibit diverse array symptoms significant heterogeneity presentations, posing challenges to precise decision-making. Accurate selection may provide further insight personalized management strategies. Methods: Latent profile analysis (LPA) was performed determine...
Objective: To explore the clinicopathological features of rectal neuroendocrine tumor (R-NET) G2, identify prognostic factors, and summarize treatment experience. Methods: The clinical data patients diagnosed with R-NET G2 by pathological diagnosis admitted to Cancer Hospital Chinese Academy Medical Sciences from January 2003 September 2023 were retrospectively analyzed. Fisher's exact test Kaplan-Meier curves performed analyze association between prognosis. Results: A total 22 enrolled in...
This study aims to investigate the impacts of failure pelvic compensation (FPC), as determined by variations in spinopelvic alignment during transition from supine upright position, on surgical outcomes patients with adult spinal deformity (ASD). A total 125 ASD who underwent posterior correction surgery a minimum follow-up two years were enrolled. Radiographic outcomes, including thoracic kyphosis, lumbar lordosis, sacral slope (SS), tilt (PT), incidence, T1-pelvic-angle and sagittal...
Aims Adult spinal deformity (ASD) surgery can reduce pain and disability. However, the actual surgical efficacy of ASD in doing so is far from desirable, with frequent complications limited improvement quality life. The accurate prediction outcome crucial to process clinical decision-making. Consequently, aim this study was develop validate a model for predicting an ideal (ISO) two years after surgery. Methods We conducted retrospective analysis 458 consecutive patients who had undergone...
Objective: To evaluate the impacts of perioperative nutritional screening and management on postoperative infectious complications in geriatric degenerative spinal deformity surgery. Methods: This retrospective cohort study included elderly patients with who underwent open posterior thoracolumbar fusion at Xuanwu Hospital, Capital Medical University, from February 2018 to October 2022. A total 139 malnutrition or risk malnutrition, as identified using Mini Nutritional Assessment-Short Form...
To investigate the effectiveness of digital three-dimensional (3D) assisted unilateral biportal endoscopy (UBE) in treatment highly isolated lumbar disc herniation (LDH) with translaminar approach. The clinical data 59 patients who met selection criteria and underwent UBE due to LDH between January 2022 December 2023 were retrospectively analyzed. Among them, 25 cases treated 3D approach (observation group) 34 interlaminar (control group). There was no significant difference gender, age,...
Posterior pedicle fixation technique is a common method for treating thoracolumbar burst fractures, but the effect of different techniques on postoperative spinal mechanical properties has not been clearly defined, especially adjacent segments. A finite element model T10-L2 with moderate T12 vertebra fracture was constructed to investigate biomechanical behavior three posterior screw techniques. Compared traditional short-segment 4 (TS-4) and intermediate long-segment 6 (IL-6), mono-segment...
Abstract Background Degenerative disorders of the lumbar spine decrease mobility and quality life elderly patients. Lumbar fusion surgery is primary method treating degenerative disorders; however, surgical stress response associated with major has been linked to pathophysiological changes in elderly, resulting undesirable postoperative morbidity, complications, pain, fatigue, extended convalescence. In present study, we aimed determine whether enhanced recovery after significantly improved...
Objective Emerging evidence links perturbations in the microbiome to neurodegeneration amnestic mild cognitive impairment (aMCI) and Alzheimer’s disease (AD) surgical stress. In this study, we attempted identify preoperative differences intestinal microbiota (IM) barrier function between pAD [prodromal AD: Subjective decline (SCD) aMCI] patients normal neurocognition (NC) patients. Additionally, potential associations IM function, inflammation, clinical characteristics of were evaluated....
Abstract Background Enhanced recovery after surgery (ERAS) program is an evidence-based improvement over non-ERAS traditional care. The aim of the present study was to analyze safety, feasibility, and efficacy ERAS in patients 70 years undergoing lumbar arthrodesis by comparison with Methods During January 2018 December 2018, enrolled received care, while implemented from 2019. Demographic characteristics, comorbidities, surgical data postoperative parameters were collected all patients....
To analyze the correlation between changes in cervical curvature and sagittal parameters of spino-pelvic clinical efficacy after posterior laminoplasty (LP).The patients with spondylosis treated LP from June 2018 to December 2020 were reviewed. The preoperative follow-up spine full-length films measured. measured data included C2-C7 Cobb angle, C2-7 vertical axis (SVA), T1 slope (T1S), pelvic incidence, sacral (SS), tilt (PT), lumbar lordosis (LL), thoracic kyphosis (TK), C7-SVA. Japanese...