A5100396150- Cardiac, Anesthesia and Surgical Outcomes
- Spine and Intervertebral Disc Pathology
- Anesthesia and Pain Management
- Enhanced Recovery After Surgery
- Coronary Interventions and Diagnostics
- Spinal Fractures and Fixation Techniques
- Actinomycetales infections and treatment
- Peripheral Artery Disease Management
- Oral microbiology and periodontitis research
- Scoliosis diagnosis and treatment
- CNS Lymphoma Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Endometriosis Research and Treatment
- Antimicrobial Resistance in Staphylococcus
- Mycobacterium research and diagnosis
- Tissue Engineering and Regenerative Medicine
- Pelvic and Acetabular Injuries
- Hip and Femur Fractures
- Infectious Diseases and Mycology
- Acupuncture Treatment Research Studies
- Prosthetics and Rehabilitation Robotics
- Medical Image Segmentation Techniques
- Urinary Bladder and Prostate Research
- Soft Robotics and Applications
Capital Medical University
2010-2025
Beijing Chao-Yang Hospital
2017-2025
Peking Union Medical College Hospital
2024-2025
Beijing Hospital of Traditional Chinese Medicine
2023-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
National Clinical Research Center for Digestive Diseases
2020-2024
Beijing Ditan Hospital
2024
Beijing Anzhen Hospital
2021-2023
Beijing Institute of Petrochemical Technology
2022
Beijing Geriatric Hospital
2022
Background: Frailty is recognized as a surrogate for physiological age and has been established valid independent predictor of postoperative morbidity, mortality, complications. ERAS can enhance surgical safety by minimizing stress responses in frail patients, enabling surgeons to discharge patients earlier. However, the question whether what extent frailty impacts post-ERAS outcomes older remains. Materials Methods: An evidence-based program was implemented our center from January 2019....
Introduction Vancomycin-resistant Enterococcus faecium (VRE-fm) biofilms pose a significant clinical challenge due to the limited effectiveness of traditional antibiotics. This study investigates potential γ-linolenic acid (GLA) as novel antibiofilm agent. Methods Transcriptome analysis was performed on V27 isolate, comparing cells in mature treated with and without GLA. The findings were further validated using qRT-PCR six VRE-fm isolates two E. faecalis isolates. Results revealed...
A nano-enabled drug delivery acupuncture technology (nd-Acu) is developed that based on traditional needles where the stainless-steel surface designed to deliver various payload molecules. To create nd-Acu platform, an electrochemistry procedure used attach methyl salicylate-modified cyclodextrin in which sugar rings allow encapsulation of structurally defined single or multiple molecules via inclusion complexation process. Drug loading and release profile are first studied using fluorescent...
Abstract Background Degenerative disorders of the lumbar spine decrease mobility and quality life elderly patients. Lumbar fusion surgery is primary method treating degenerative disorders; however, surgical stress response associated with major has been linked to pathophysiological changes in elderly, resulting undesirable postoperative morbidity, complications, pain, fatigue, extended convalescence. In present study, we aimed determine whether enhanced recovery after significantly improved...
Abstract Background Enhanced recovery after surgery (ERAS) program is an evidence-based improvement over non-ERAS traditional care. The aim of the present study was to analyze safety, feasibility, and efficacy ERAS in patients 70 years undergoing lumbar arthrodesis by comparison with Methods During January 2018 December 2018, enrolled received care, while implemented from 2019. Demographic characteristics, comorbidities, surgical data postoperative parameters were collected all patients....
The arterial circulatory system diseases are common in clinical practice, and their treatment options have been of great interest due to high morbidity mortality. Drug-eluting balloons, as a new type endovascular interventional option, can avoid the long-term implantation metal stents is angioplasty without stents, so drug-eluting balloons better therapeutic effects some initially used practice. In this review, we first describe development, process, mechanism balloons. Then summarize...
This study aimed to determine the healing effect of hydrogen-rich water (HRW) on radiotherapy-induced skin injury. Rats were irradiated with a 6 MeV electron beam from Varian linear accelerator. After wound formation, rats individually administrated distilled water, HRW (1.0 ppm) or (2.0 ppm). We measured time and observed rate wounded surface. irradiation, malondialdehyde (MDA) content superoxide dismutase (SOD) activity in tissues evaluated, as determined using an MDA SOD assay kit....
Elderly patients are less likely to recover from lumbar spine fusion (LSF) as rapidly compared with younger patients. However, there is still a lack of research on the effect early ambulation elderly undergoing LSF surgery for degenerative disorders.
Enterococcus faecium is a leading cause of hospital-acquired infections, which has become serious public health concern. The increasing incidence vancomycin-resistant E. (VRE-fm) raises an urgent need to find new antimicrobial agents as complement traditional antibiotics. study aimed evaluate the and antibiofilm activity essential fatty acids (EFAs) against VRE-fm, further explore molecular mechanism EFAs.The microdilution broth method was used for susceptibility testing with antibiotics...
The prevalence of degenerative spinal deformity (DSD) and the increased cost correction surgery impose substantial burdens on health care insurance system. aim our study was to investigate effects implementation Enhanced Recovery After Surgery (ERAS) protocol postoperative outcomes after complex surgery.A retrospective analysis prospectively established database DSD performed. consecutive patients who underwent open for between August 2016 February 2022 were reviewed. We extracted...
Conditional neuromodulation is a form of closed-loop bladder control where neurostimulation applied in reaction to pressure changes. Current methods based on external catheters have limited utility for chronic ambulatory therapy. We developed wireless monitor provide real-time, catheter-free detection contractions. The device sized implantation the muscle. consists an ultra-low-power application specific integrated circuit (ASIC), micro-electro-mechanical (MEMS) sensor, RF antennas, and...
Wound complications are associated with worse satisfaction and additional costs in patients undergoing posterior lumbar fusion (PLF) surgery, the relationship between enhanced recovery after surgery (ERAS) pathway wound remains poorly characterized.In this retrospective single-center study, we compared 530 receiving ERAS care previous non-ERAS group. The primary aim of our study was to identify program incidence postoperative wound-related other following PLF surgery; outcomes included...
Abstract Background With the increase of detection rate and long treatment period, nocardiosis has become a noticeable problem in China. However, there are limited large-scale studies on epidemiology antimicrobial susceptibility profiles clinical Nocardia spp. The present study aimed to explore species distribution drug pattern 82 isolates from three tertiary hospitals China by multilocus sequence analysis (MLSA) broth microdilution (BMD) method. Results Pulmonary (90.2%) was most common...
Nanotechnology may help provide new evidence to verify acupuncture theory, improve the features of needles and their clinical effects by combining with drug delivery, even enable therapeutic methods.
Therapeutic angiogenesis has garnered significant attention as a potential treatment strategy for lower limb ischemic diseases. Although hepatocyte growth factor (HGF) been identified key promoter of therapeutic angiogenesis, its clinical application is limited due to short half-life. In this study, we successfully developed and characterized platelet membrane-coated HGF-poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs). These demonstrated enhanced capabilities promote endothelial...
Background: In the follow-up after internal fixation of thoracolumbar fractures, imaging some patients shows "crater-like" collapse superior endplate injured vertebra, with variable area and depth, even involving anterior edge vertebral body. Though many papers had described phenomenon, but nearly no one did biomechanical research about this. So we this in a creative way by using finite element model. Methods: A healthy male volunteer was selected. The 64-slice thin-section spiral computed...
Enhanced recovery after surgery (ERAS) for spinal is new; specifically, an ERAS program elderly patients lacking. Geriatric have special characteristics that result in further harm by surgical stress. interventions are designed to improve and can substantial benefits clinical outcomes cost-effectiveness. We aimed determine whether significantly improved satisfaction with long-level lumbar fusion.Patients >70 years old disc herniation or stenosis who underwent fusion of ≥3 levels from July...
The thoracic ossification of the posterior longitudinal ligament (T‑OPLL) can cause spinal stenosis, which results in intractable myelopathy and radiculopathy. Our previous whole‑genome sequencing study first reported rs199772854 interleukin 17 receptor C (IL17RC) gene as a potentially pathogenic loci for T‑OPLL. aim present was to examine effects IL17RC rs199772854A site mutation on osteogenesis by establishing model osteogenic differentiation. wild‑type mouse embryonic osteoblast (3T3‑E1)...