A5101671491- Spine and Intervertebral Disc Pathology
- Neuroscience and Neuropharmacology Research
- Insect Utilization and Effects
- Light effects on plants
- Wound Healing and Treatments
- Spinal Fractures and Fixation Techniques
- Urinary Bladder and Prostate Research
- Genetics and Neurodevelopmental Disorders
- Salivary Gland Disorders and Functions
- Sexual function and dysfunction studies
- T-cell and B-cell Immunology
- Medical Imaging and Analysis
- Immune Response and Inflammation
- Systemic Lupus Erythematosus Research
- Neurogenesis and neuroplasticity mechanisms
- Platelet Disorders and Treatments
- Photosynthetic Processes and Mechanisms
- Circadian rhythm and melatonin
- Musculoskeletal pain and rehabilitation
- Sphingolipid Metabolism and Signaling
- Nutrition and Health in Aging
- Spinal Hematomas and Complications
- Hormonal and reproductive studies
- Silk-based biomaterials and applications
- Edible Oils Quality and Analysis
Binzhou University
2014-2025
Binzhou Medical University
2014-2025
Huazhong University of Science and Technology
2009-2024
Tongji Hospital
2010-2024
Henan Energy & Chemical Industry Group (China)
2024
Xuzhou Medical College
2015-2024
Wuhan University
2023
Renmin Hospital of Wuhan University
2023
Chinese PLA General Hospital
2021-2023
West China Second University Hospital of Sichuan University
2021
Although the effects of melatonin on plant abiotic and biotic stress resistance have been explored in recent decades, accumulation endogenous plants its influence fruit quality remains unclear. In present study, levels expression profiles five synthesis genes were investigated during leaf development sweet cherry (Prunus avium L.). Melatonin was strongly accumulated young fruits leaves, then decreased steadily with maturation. Transcript PacTDC PacSNAT highly correlated content both...
This study developed a novel and green method to produce fragrant sesame oil using microwaves subcritical extraction (SBE). Sesame seeds were microwaved at 540 W for 0-9 min before propane 40 °C 0.5 MPa. SBE caused less deformation the cellular microstructure of cotyledons while dramatically improving yield (96.7-97.1 %) compared screw processing (SP) (53.1-58.6 %). improved rates γ-tocopherol (381.1-454.9 μg/g) lignans (917.9-970.4 mg/100 g) in SP (360.1-443.8 μg/g 872.8-916.8 g,...
Receptor‐interacting protein 3‐ (RIPK3‐) modulated necroptosis plays a critical role in cardiac remodelling after myocardial infarction (MI). However, the precise regulatory mechanism is not fully elucidated yet. In present study, we showed that RIPK3 expression was upregulated tissue MI mouse model by coronary artery ligation, as well cardiomyocytes following hypoxic injury vitro . The increase of found to be accompanied severe remodelling, dysfunction, and higher mortality. Elevated...
To compare the clinical efficacy of posterior percutaneous endoscopic cervical discectomy (PECD) with unilateral biportal endoscopy (UBE) key-hole techniques for treating spondylotic radiculopathy (CSR). A retrospective study was performed patients CSR treated by PECD (n = 40) and UBE 30). Patients background, operative data, radiographic measurements were obtained. The visual analog scale (VAS) neck disability index (NDI) recorded preoperatively 3 months 2 years postoperatively, modified...
To investigate the effectiveness of digital three-dimensional (3D) assisted unilateral biportal endoscopy (UBE) in treatment highly isolated lumbar disc herniation (LDH) with translaminar approach. The clinical data 59 patients who met selection criteria and underwent UBE due to LDH between January 2022 December 2023 were retrospectively analyzed. Among them, 25 cases treated 3D approach (observation group) 34 interlaminar (control group). There was no significant difference gender, age,...
According to the previous research, metformin, a medication utilized for type 2 diabetes management, inhibits neural aging and reduces infarct size by enhancing angiogenesis in mouse stroke model. What is more, metformin administration also promotes precursor cells proliferation, migration, as well differentiation newborn mice with hypoxia–ischemia brain injury. However, whether regulates neurogenesis an adult rat ischemia/reperfusion (I/R) model remains unclear. The current research found...
Abstract Background Lumbar disc herniation (LDH) is one of the most common diseases spine, and migrated LDH a more serious type, associated with nerve root function injury or abnormality. Regarding increasing surgery adoption treating LDH, we aimed to investigate clinical efficacy safety discectomy novel technique–one-hole split endoscope (OSE) technique. Methods This was retrospective analysis treated between December 2020 September 2021. Hospitalization time, operative duration,...
Rheumatoid arthritis (RA) and osteoarthritis (OA) are common rheumatic disorders that primarily involve joints. The inflammation of the synovium can be observed in both two diseases. Synovial fibroblasts (SFs) play an important role inflammatory process synovium. functional states synovial heterogeneous, detailed transition their is still unclear. By using transcriptomic data SFs at a single-cell level, we found similar for RA OA. We also identified potential regulatory effects WNT signaling...
Lumbar disk herniation (LDH) is one of the most common diseases spine, especially occurring in L4-5 and L5-S1 intervertebral disks, surgery a choice when conservative treatment ineffective. The purpose this study to investigate clinical efficacy radiologic outcomes one-hole split endoscopy (OSE) technique versus unilateral biportal (UBE) lumbar (LDH).A total 133 patients single center surgically treated for LDH between 2019 2021 were retrospectively included study, which 70 by UBE rest OSE...
Objective . The aim of this study was to characterize the subsets circulating CD56 + NK cells in pSS patients and their potential value diagnosis and/or prediction prognosis with pSS. Methods We included 52 fulfilling 2002 AECG criteria or 2012 ACR 20 age- gender-matched healthy volunteers. frequency absolute number cell peripheral blood samples were detected by flow cytometry. Other laboratory parameters such as IgG level complement protein levels extracted from clinical system. Results...
This study aimed to optimize the subcritical butane extraction of black soldier fly larvae (Hermetia illucens) using response surface methodology (RSM) and evaluate nutritional properties oil (BSFLO) meal (BSFLM) products. A Box-Behnken design was conducted reveal effects temperature (25–65 °C), time (20–60 min) number extractions (1–5 times) on yield. Results showed that yield significantly affected by as well interaction extractions. The optimal conditions were 35 °C, 50 min/time 5 times...
Abstract Background Neurogenic erectile dysfunction (NED) caused by cavernous nerve (CN) injury is a typical complication after pelvic surgery, which lacks efficient treatments. Acetyl‐L‐carnitine (ALCAR) has been proven to promote repair. Objectives To investigate the effect and potential mechanism of ALCAR in treatment NED. Materials methods Thirty‐two rats were randomly divided into bilateral CN (BCNI) group, BCNI + lower‐dose (50 mg/kg/day) higher‐dose (100 sham‐operated group. Erectile...
Evidence suggests the involvement of N‑methyl‑D‑ aspartate receptors (NMDAR) in regulation neurogenesis. Functional properties NMDAR are strongly influenced by type NR2 subunits receptor complex. NR2A‑ and NR2B‑containing expressed neonatal forebrain regions, such as subventricular zone (SVZ). The aim present study was to examine effect protein expression hypoxic‑ischemic injury 2A 2B SVZ rats. Expression these other proteins interest performed using immunohistochemistry. results showed that...
The aim of this study was to investigate whether the level serum microRNA-199a/b-3p (miR-199a/b-3p) can serve as a predictor treatment response transarterial chemoembolization (TACE) in patients with hepatocellular carcinoma (HCC).Serum miR-199a/b-3p expression measured 132 HCC before TACE (t1) and 3-5 days after (t2). Additionally, 126 these had levels 4 weeks (t3) second (t4). Serum were compared those 50 healthy controls. Correlations between clinicopathologic factors tumor responsiveness...
Sphingomyelin synthase 1 (SMS1) has been reported to participate in hepatitis and atherosclerosis. However, its role autoimmune response is not clear. This study investigates the possible involvement of SMS1 B-cell activation lupus-like autoimmunity.SMS1 knockout animal model SLE patient samples were utilized. associated signal transduction detected by flow cytometry, confocal analysis western blotting. The expression B cells was measured real-time qPCR.SMS1 deficiency suppressed culture,...
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), also known as National Institutes of Health (NIH) type III prostatitis, is a common disorder with an unclear etiology and no curative treatments. Based on the presence or absence leukocytes in expressed prostatic secretion (EPS), CP/CPPS classified further into IIIa (inflammatory) IIIb (noninflammatory) subtypes. However, severity symptoms not entirely consistent white blood cell (WBC) count. Following preliminary finding link...
Abstract Background Among erectile dysfunction (ED) caused by metabolic abnormalities, diabetes mellitus‐induced ED (DMED) progresses rapidly, manifests with severe symptoms, and shows reduced responsiveness to conventional medications. Hyperglycemia in the corpus cavernosum has been linked induction of both ferroptosis oxidative stress, which are mediated nuclear factor E2 related 2 (Nrf2). Hesperidin (Hes), a flavonoid compound, revealed activate Nrf2 certain diabetic complications, yet...