A5100779792- Elbow and Forearm Trauma Treatment
- Spine and Intervertebral Disc Pathology
- Orthopedic Surgery and Rehabilitation
- Shoulder Injury and Treatment
- Diabetic Foot Ulcer Assessment and Management
- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Ferroptosis and cancer prognosis
- RNA modifications and cancer
- Monoclonal and Polyclonal Antibodies Research
- Chemokine receptors and signaling
- Musculoskeletal Disorders and Rehabilitation
- Neurogenetic and Muscular Disorders Research
- Respiratory viral infections research
- Musculoskeletal pain and rehabilitation
- Hepatitis C virus research
- NF-κB Signaling Pathways
- Blood donation and transfusion practices
- Peripheral Nerve Disorders
- Synthesis and Biological Evaluation
- Gastrointestinal Bleeding Diagnosis and Treatment
- Retinoids in leukemia and cellular processes
- Selenium in Biological Systems
- Liver Disease Diagnosis and Treatment
- Advanced Differential Equations and Dynamical Systems
Northern Jiangsu People's Hospital
2025
Westlake University
2024
Southwest Medical University
2022-2024
Sichuan Cancer Hospital
2024
University of Electronic Science and Technology of China
2024
Fujian Medical University
2024
Binzhou University
2022-2023
Binzhou Medical University
2022-2023
Guiyang Medical University
2023
The Affiliated Yongchuan Hospital of Chongqing Medical University
2018-2022
Hexanucleotide repeat expansions in the C9orf72 gene are most common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. Due to lack trunk neuromuscular organoids (NMOs) from ALS patients' induced pluripotent stem cells (iPSCs), an organoid system was missing model spinal neurodegeneration. With patient-derived iPSCs isogenic controls, we used NMO containing cord neural peripheral muscular tissues show that NMOs could defects ALS, including contraction weakness,...
ABSTRACT The Paramyxovirus respiratory syncytial virus (RSV) is the primary etiologic agent of serious epidemic lower tract disease in infants, immunosuppressed patients, and elderly. Lower infection with RSV characterized by a pronounced peribronchial mononuclear infiltrate, eosinophilic basophilic degranulation. Because replication restricted to airway epithelial cells, where induces potent expression chemokines, epithelium postulated be initiator pulmonary inflammation infection. spectrum...
To compare the clinical efficacy of posterior percutaneous endoscopic cervical discectomy (PECD) with unilateral biportal endoscopy (UBE) key-hole techniques for treating spondylotic radiculopathy (CSR). A retrospective study was performed patients CSR treated by PECD (n = 40) and UBE 30). Patients background, operative data, radiographic measurements were obtained. The visual analog scale (VAS) neck disability index (NDI) recorded preoperatively 3 months 2 years postoperatively, modified...
The pneumovirus respiratory syncytial virus (RSV) is a leading cause of epidemic tract infection. Upon entry, RSV replicates in the epithelial cytoplasm, initiating compensatory changes cellular gene expression. In this study, we have investigated RSV-induced nuclear proteome A549 alveolar type II-like cells by high-resolution two-dimensional gel electrophoresis (2DE). Replicate 2D gels from uninfected and RSV-infected nuclei were compared for protein We identified 24 different proteins...
Peoniflorin (PF), extracted from the root of Paeonia lactiflora Pall., has been reported to have anti-inflammation and antioxidant effects in several animal models. Herein, we investigated protective PF against hydrogen peroxide (H(2)O(2))-induced oxidative damage human umbilical vein endothelial cells (HUVECs). HUVECs were treated by H(2)O(2) (240 µmol/L) with or without PF. significantly increased percent cell viability injured using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium...
Abstract Background Lumbar disc herniation (LDH) is one of the most common diseases spine, and migrated LDH a more serious type, associated with nerve root function injury or abnormality. Regarding increasing surgery adoption treating LDH, we aimed to investigate clinical efficacy safety discectomy novel technique–one-hole split endoscope (OSE) technique. Methods This was retrospective analysis treated between December 2020 September 2021. Hospitalization time, operative duration,...
Lumbar disk herniation (LDH) is one of the most common diseases spine, especially occurring in L4-5 and L5-S1 intervertebral disks, surgery a choice when conservative treatment ineffective. The purpose this study to investigate clinical efficacy radiologic outcomes one-hole split endoscopy (OSE) technique versus unilateral biportal (UBE) lumbar (LDH).A total 133 patients single center surgically treated for LDH between 2019 2021 were retrospectively included study, which 70 by UBE rest OSE...
The aim of this study was to evaluate the diagnostic value high-frequency ultrasonography in detecting atrophy foot muscles Chinese patients type 2 diabetes mellitus (T2DM). T2DM with (n = 56) or without 50) diabetic peripheral neuropathy (DPN) and control subjects were enrolled. nondominant all examined ultrasonography. transverse diameter, thickness, cross-sectional area extensor digitorum brevis muscle (EDB) thickness first interstitium (MILs) measured. results showed that...
Abstract Advances in the treatment of multiple myeloma have been driven by development new modalities, including proteasome inhibitors, immunomodulatory agents and monoclonal antibodies. TAK-169 is an engineered toxin body (ETB) comprising a proprietarily engineered, deimmunized form ribosome inactivating Shiga-like A-subunit (SLTA) genetically fused to antibody fragment that specifically targets CD38 cell surface receptor. Although poorly internalizing receptor, able efficiently internalize...
Background Tertiary lymphoid structures (TLS) is a particular component of tumor microenvironment (TME). However, its biological mechanisms in colorectal cancer (CRC) have not yet been understood. We desired to reveal the TLS gene signature CRC and evaluate role prognosis immunotherapy response. Methods The data was sourced from Cancer Genome Atlas (TCGA) Gene Expression Omnibus (GEO) databases. Based on TLS-related genes (TRGs), related subclusters were identified through unsupervised...
Autism spectrum disorder (ASD) negatively impacts mental health, particularly in mothers of autistic children who experience heightened stress. Applied behaviour analysis (ABA) and music therapy are recognised interventions for improving ASD symptoms. However, the specific benefits parent-child ABA their remain uncertain. This study evaluated effects on preschool mothers.
Abstract One new compound, palmarumycin LP1 (I), is isolated together with three known spiro‐dioxynaphthalene compounds, related to palmarumycins.
In order to explore the role of red blood cell distribution width in diagnosis and treatment gastrointestinal bleeding, this paper applies map feature recognition technology broadband constructs an intelligent model. To extract content-level features image safely effectively, introduces mechanism jitter quantization at lowest frequency image. addition, article employs experimental approach investigate function management bleeding elderly. Finally, establishes group a control then performs...