A5100400997- Food Drying and Modeling
- Microbial Inactivation Methods
- Microwave-Assisted Synthesis and Applications
- Microwave and Dielectric Measurement Techniques
- Osteoarthritis Treatment and Mechanisms
- Retinal Diseases and Treatments
- Liver Disease Diagnosis and Treatment
- Mesenchymal stem cell research
- Retinal and Macular Surgery
- Spinal Cord Injury Research
- Spine and Intervertebral Disc Pathology
- Phytochemicals and Antioxidant Activities
- Lymphatic System and Diseases
- Growth Hormone and Insulin-like Growth Factors
- Intraocular Surgery and Lenses
- Cardiac Ischemia and Reperfusion
- Neuroinflammation and Neurodegeneration Mechanisms
- Sulfur Compounds in Biology
- Pancreatic function and diabetes
- Extracellular vesicles in disease
- Fluid Dynamics and Mixing
- Functional Brain Connectivity Studies
- Traditional Chinese Medicine Studies
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Horticultural and Viticultural Research
Zhejiang University
2013-2025
Beijing Children’s Hospital
2018-2025
Fujian Medical University
2025
Capital Medical University
2018-2025
People 's Hospital of Jilin Province
2025
Nantong University
2013-2024
Guizhou Normal University
2024
Zhejiang Chinese Medical University
2018-2024
Sun Yat-sen University
2010-2024
University of Tennessee at Knoxville
2019-2024
H7N9 viruses quickly spread between mammalian hosts and carry the risk of human-to-human transmission, as shown by 2013 outbreak. Acute respiratory distress syndrome (ARDS), lung failure, acute pneumonia are major diseases in patients. Transplantation mesenchymal stem cells (MSCs) is a promising choice for treating virus-induced pneumonia, was used to treat H7N9-induced ARDS 2013. The transplant MSCs into patients with conducted at single center through an open-label clinical trial. Based on...
Hexanucleotide repeat expansions in the C9orf72 gene are most common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. Due to lack trunk neuromuscular organoids (NMOs) from ALS patients' induced pluripotent stem cells (iPSCs), an organoid system was missing model spinal neurodegeneration. With patient-derived iPSCs isogenic controls, we used NMO containing cord neural peripheral muscular tissues show that NMOs could defects ALS, including contraction weakness,...
In this study, the regulatory role and mechanisms of tantalum (Ta) particles in bone tissue microenvironment are explored. Ta particle deposition occurs both clinical samples animal tissues following porous implantation. Unlike titanium (Ti) promoting M1 macrophage (Mϕ) polarization, regulating calcium signaling pathways M2 Mϕ polarization. Ta-induced enhances marrow-derived mesenchymal stem cells (BMSCs) proliferation, migration, osteogenic differentiation through exosomes (Exo) by...
A 3-dimensional finite-element model coupling electromagnetics and heat mass transfer was developed to understand the interactions between microwaves fresh mashed potato in a 500 mL tray. The validated by performing heating of from 25 °C on rotating turntable microwave oven, rated at 1200 W, for 3 min. simulated spatial temperature profiles top bottom layer showed similar hot cold spots when compared thermal images acquired an infrared camera. Transient 6 locations collected fiber-optic...
In this study, nonvolatile metabolomics and proteomics were applied to investigate the change mechanism of flavonoid glycoside compounds during withering processing white tea. With extension time, content main significantly decreased, then aglycones water-soluble saccharides contents increased. However, trends these inconsistent with expression pattern related biosynthesis pathway proteins, indicating that degradation glycosides might exist in process One co-expression network was highly...
Abstract Evidence has indicated abnormalities of thalamo-cortical functional connectivity (FC) in bipolar disorder during a depressive episode (BDD) and major (MDD). However, the dynamic FC (dFC) within this system is poorly understood. We explored dFC pattern by dividing thalamus into 16 subregions combining with sliding-window approach. Correlation analysis was performed between altered variability clinical data. Classification linear support vector machine model conducted. Compared...
Background: Invasive pulmonary aspergillosis (IPA) in acute-on-chronic liver failure (ACLF) patients is associated with a high mortality.But the clinical characteristics of and risk factors for IPA among ACLF remains unclear.This study was aimed at assessing manifestation, antifungal medications as well mortality due to First Affiliated Hospital, College Medicine, Zhejiang University.Patients Methods: Patients who were diagnosed proven or probable by laboratory parameters from 1 December...
Morphometric studies demonstrated wide-ranging distribution of brain structural abnormalities in major depressive disorder (MDD).This study explored the progressive gray matter volume (GMV) changes pattern network 108 MDD patients throughout illness duration by using voxel-based morphometric analysis.The causal covariance method was applied to map effects GMV alterations between original source and other regions as prolonged MDD. This carried out utilizing Granger causality analysis...
Abstract Medical diagnosis technology based on convolutional neural networks (CNNs) has achieved good performance. In this study, we collected serum samples from 38 glioma patients and 45 healthy controls used partial least squares (PLS) analysis to reduce the dimension of data. Different levels noise were added reduced data onto augmentation, AlexNet, ResNet, GoogLeNet fine‐tuning models applied for classification. To evaluate performance models, five‐fold cross‐validation. The accuracy...
This work aims to explore the long-term prognosis of hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF). In this prospective study, eligible inpatients with HBV-ACLF are enrolled and followed up from December 2012 February 2023, for clinical events, laboratory tests at least every 6 months. Overall, survival rates 28 days, 90 1 year, 5 years, 8 years 64.7%, 48.8%, 46.1%, 43.8%, 42.2%, respectively. Among 8-year mortality transplant cases, ACLF survivors (who survived over...
Abstract Objective Idiopathic infantile hypercalcemia (IIH) is a rare disorder of PTH-independent hypercalcemia. CYP24A1 and SLC34A1 gene mutations cause two forms hereditary IIH. In this study, the clinical manifestations molecular aspects six new Chinese patients were investigated. Methods The laboratory study with idiopathic analyzed retrospectively. Results Five diagnosed hypercalcemia, hypercalciuria, bilateral medullary nephrocalcinosis. Their symptoms biochemical abnormalities...
The aim of this study was to explore the association between maternal pre-pregnancy body mass index (BMI) and neonatal birth weight in pregnancies with gestational diabetes mellitus (GDM). This a retrospective cohort conducted January 2019 June 2020 at university hospital Fuzhou, China. Pre-pregnancy BMI used categorize 791 pregnant women as underweight (3.03%), normal (51.71%), overweight (32.74%), obese (12.52%). Among babies, 11.63% were small for age (SGA), 77.37% weight, 11.00% large...