A5103124805- Cervical Cancer and HPV Research
- Reproductive tract infections research
- Endometrial and Cervical Cancer Treatments
- Pelvic floor disorders treatments
- Ovarian cancer diagnosis and treatment
- Pregnancy and preeclampsia studies
- Endometriosis Research and Treatment
- Gut microbiota and health
- Inflammatory Biomarkers in Disease Prognosis
- Immune Response and Inflammation
- Uterine Myomas and Treatments
- Prenatal Screening and Diagnostics
- Syphilis Diagnosis and Treatment
- Pregnancy-related medical research
- Gestational Trophoblastic Disease Studies
- Pelvic and Acetabular Injuries
- Genital Health and Disease
- Cancer Risks and Factors
Fujian Medical University
2020-2023
This study aimed to explore the changes of vaginal microbiota and enzymes in women with high-risk human papillomavirus (HR-HPV) infection cervical lesions. A total 448 participants were carried out HPV genotyping, cytology tests, microecology 28 treated as sub-samples, which samples characterized by sequencing bacterial 16S V4 ribosomal RNA (rRNA) gene region. The found prevalence HR-HPV was higher patients BV (P = 0.036). rate 72.73% G. vaginalis women, significantly than that lactobacillus...
Abstract There is evidence that coinfection of cervicovaginal high‐risk human papillomavirus (HR‐HPV) and bacteria common in women childbearing age. However, the relationship between bacterial vaginosis (BV) persistent HR‐HPV infection age underlying mechanisms remain unclear. In this study, we determined whether BV affects aged 20–45 years explored possible their interactions. From January 1 to April 30, 2020, recruited with without at a ratio 1:2 from Fujian Maternity Child Health...
This study assessed the predictive value of preoperative systemic immune-inflammatory index (SII) for lymph node metastasis (LNM) in endometrial cancer (EC) patients.We retrospectively included 392 EC patients between January 2013 and 2019. Data on clinical indicators including age, body mass (BMI), menopause, serum inflammatory immune index, tumor markers, history diabetes hypertension, stage, histological type, myometrial invasion (MI) were collected. The association LNM was evaluated.The...
Objective: According to the 2019 American Society for Colposcopy and Cervical Pathology (ASCCP) recommendations, women with a positive high-risk human papillomavirus (HR-HPV) diagnosis low-grade cervical intraepithelial lesion (LSIL) cytology result should be referred further colposcopy examination.However, this strategy results in over-treatment several cases.In study, we assessed performance of extended HR-HPV genotyping simultaneous LSIL aim improving current triage strategy.Methods: This...
China's Fujian Cervical Pilot Project (FCPP) transitioned cervical cancer screening from high-risk human papillomavirus (HR-HPV) nongenotyping to genotyping. We investigated the clinical impact of this introduction, comparing performance indicators between HR-HPV genotyping combined with cytology (HR-HPV period) and previous period).A retrospective population-based cohort study was performed using data FCPP for China. obtained period 1 January 2012 31 December 2013, 2014 2016. Propensity...
We investigated the relationship between metabolic syndrome (MetS) and its components erythrocyte parameters such as red blood cell count (RBC) hemoglobin (Hb) levels, their association with risk of deep myometrial invasion in endometrioid endometrial carcinoma (EEC).A total 473 women diagnosed EEC January 2012 December 2018 were included study. MetS was using a modified version Chinese Diabetes Society 2004 criteria. Demographic clinical characteristics stratified by compared. Logistic...
The natural history of human papillomavirus (HPV) is influenced by vaginal microenvironment disorders, such as bacterial vaginosis (BV). objective this study was to assess the epidemiology HPV combined with BV prevalence among Chinese women aged 20-35 years.A total 2000 sexually active years voluntarily enrolled in and underwent a ThinPrep cytologic test PCR-reverse dot blot genotyping (PCR-RDB test). diagnosed if clue cells were observed (20% more than epithelial cells).The overall...
Background: The diagnosis of postpartum pelvic organ prolapse (POP) relies on symptoms combined with prolapse-quantification (POP-Q) and lacks serological indicators. objective this study was to assess serum elastin, type I collagen, miRNA-30d, miRNA-181a in the early period identify hematologic predictors POP. Material Methods: included 1013 42- 60-day-postpartum women who had delivered at Quanzhou Women’s Children’s Hospital from October 1, 2016, 31, 2017. This performed accordance...
Gestational trophoblastic disease (GTD) is a group of interrelated but distinct diseases and has serious impact on the reproductive health women. To analyze expression Nanog in GTD to evaluate its potential predict development gestational neoplasia (GTN).The study included 41 normal first-trimester placentas matched by age 53 regressed-hydatidiform-moles (rHMs), 56 malignant-HMs (mHMs) 17 choriocarcinomas (CCAs) evaluated immunohistochemistry. The chi-square test, ANOVA, Fisher's exact test...