- Essential Oils and Antimicrobial Activity
- Curcumin's Biomedical Applications
- Phytochemicals and Antioxidant Activities
- Natural product bioactivities and synthesis
- Computational Drug Discovery Methods
- Phytochemistry and Biological Activities
- Natural Antidiabetic Agents Studies
- Medicinal Plants and Neuroprotection
- Ginger and Zingiberaceae research
- Complementary and Alternative Medicine Studies
- Herbal Medicine Research Studies
- Pharmacological Effects of Natural Compounds
- Gut microbiota and health
- Dye analysis and toxicity
- Insect Pest Control Strategies
- Biochemical effects in animals
- Nutrition, Genetics, and Disease
- Cancer Research and Treatments
- Cancer, Lipids, and Metabolism
- Toxin Mechanisms and Immunotoxins
- Piperaceae Chemical and Biological Studies
- Dyeing and Modifying Textile Fibers
- Glycosylation and Glycoproteins Research
- Escherichia coli research studies
- Pharmacological Effects of Medicinal Plants
Govind Ballabh Pant University of Agriculture and Technology
2019-2024
University of Michigan–Ann Arbor
2010-2011
Centre National de la Recherche Scientifique
2011
Université Toulouse III - Paul Sabatier
2011
Institut de Pharmacologie et de Biologie Structurale
2011
Université de Toulouse
2011
University of Allahabad
2007-2010
U-M Rogel Cancer Center
2010
A robust and sensitive ultra-low flow liquid chromatography (UFLC) method that can reproducibly, at reasonable cost, detect low concentrations of piperine from human plasma is necessary. Piperine in was separated quantified by a gradient using ultraviolet detection maximal absorbance wavelength 340 nm. An aliquot injected onto reversed-phase column Waters SymmetryShield, 2.1 × 100 mm, 3.5 μm, C18 column, attached to absorbosphere, 4.6 30 guard eluted with mobile phase containing mixture...
Innate immune recognition is based on the detection, by pattern receptors (PRRs), of molecular structures that are unique to microorganisms. Lipoglycans macromolecules specific cell envelope mycobacteria and related genera. They have been described be ligands, as purified molecules, several PRRs, including C-type lectins Mannose Receptor DC-SIGN, well TLR2. However, whether they really sensed these in context a bacterium infection remains unclear. To address this question, we used model...
Acmella uliginosa, an edible herb belonging to Asteraceae family, was collected from the Terai region of Uttarakhand, India. Methanol and hexane extracts whole plant were prepared using soxhlet apparatus. The GC-MS analysis identifies 22 35 major compounds methanol which comprises 74.21% 73.20% total composition extracts, respectively. compound in 2, 4-heptadienal (7.99%) whereas trans, trans-9, 12-octadecadienoic acid propyl ester (16.96%) extract. evaluated for antioxidant...
The present study describes chemical composition, phytochemicals, antifungal activities, antioxidant assays and total phenolic content of essential oil varied polarity solvent extract from flowers Alpinia malaccensis (Burm.f.). Total 27 components were identified in by GC-MS with terpinen-4-ol (28.6%) α- terpineol (12.8%) as the main constituent. was found to have maximal levels (64.60 μg/mL) compared other extracts. assay evaluated extracts different methods revealed good-to-moderate...
The current study describes the analysis of phytochemical composition and biological activities various polarity extracts Anaphalis busua plant that was collected at an altitude 1654 m in Himalayan terrain Uttarakhand, India. were prepared by cold percolation method, which then subjected to GC-MS for analysis. A total 31 compounds identified constituted 94.95% methanolic extract. Mome inositol (31.03%) as main compound Twenty-two comprise 68.24% hexane extract identified. Tetracontane...
The aim of the present study was to assess variations in chemical composition and biological activities essential oil Curcuma longa rhizome local cultivars collected from four varied altitudes habitats Kumaun Garhwal regions Uttarakhand, India. rhizomes by hydrodistillation extraction using Clevenger apparatus. Yields 0.180% 0.273%. GC–MS analysis revealed presence turmerone, germacrone, eucalyptol, caryophyllene, ß-sesquiphellandrene, hedycaryol, α-zingiberene, α-curcumene as some major...
The plant Acmella uliginosa (Sw.) Cass. belonging to family Asteraceae was subjected hydro distillation for essential oil extraction and chemically analyzed by GC/MS its phytochemical composition. Thirty-five compounds were identified comprising 88.1% of total Limonene (12.2%) along with sesquisabinene isomer (7.3%) caryophyllene oxide (5.9%) the prominent oil. In-vitro antioxidant activity investigated DPPH free radical scavenging metal chelating having IC50 value 326.77 ± 5.34 μL 14.853...
Gummies belong to a confectionery category characterized by hydrocolloid, acting as stabilizer, forming network retain high-moisture sugar syrup, and hydrocolloids play key role in shaping the visual appeal, flavour release, texture of gel network. This study investigates potential substitution gelatin gummies with plant-based like agar-agar guar gum. It is also aimed at optimizing level functional ingredients curcumin piperine standardized through incorporation turmeric black pepper,...