A5028780184- Functional Brain Connectivity Studies
- Vestibular and auditory disorders
- Dementia and Cognitive Impairment Research
- Alzheimer's disease research and treatments
- Advanced Neuroimaging Techniques and Applications
- Amyotrophic Lateral Sclerosis Research
- Neural dynamics and brain function
- Advanced MRI Techniques and Applications
- Nerve injury and regeneration
- Mental Health Research Topics
- Hearing, Cochlea, Tinnitus, Genetics
- Clinical Nutrition and Gastroenterology
- Neurological Disease Mechanisms and Treatments
- Linguistic Education and Pedagogy
- Cancer-related molecular mechanisms research
- Pregnancy and preeclampsia studies
- Linguistic research and analysis
- Nutrition and Health in Aging
- Thyroid Disorders and Treatments
- EEG and Brain-Computer Interfaces
- Epilepsy research and treatment
- Linguistics, Language Diversity, and Identity
- Second Language Learning and Teaching
- Electrolyte and hormonal disorders
- Acute Ischemic Stroke Management
Beijing Tian Tan Hospital
2015-2025
Capital Medical University
2014-2025
National Clinical Research Center for Digestive Diseases
2015-2025
Beijing YouAn Hospital
2014-2025
University of California, San Francisco
2022-2024
Wenzhou Medical University
2024
University Memory and Aging Center
2022-2024
Anhui University of Science and Technology
2024
Jinan University
2024
Shandong University of Traditional Chinese Medicine
2020-2023
Abstract Aims Corona virus disease 2019 (COVID-19) has rapidly become the most severe public health issue all over world. Despite respiratory symptoms, hepatic injury also been observed in clinical settings. This study aimed to investigate risk factors involved with patients COVID-19. Methods A total of 85 hospitalized who were diagnosed COVID-19 Beijing You’an Hospital retrospectively analyzed. According liver function, they divided into ALT normal group (n=52) and elevation (n=33)....
Numerous studies have revealed various working memory (WM)-related brain activities that originate from cortical regions and oscillate at different frequencies. However, multi-frequency band analysis of the network in WM space remains largely unexplored. In this study, we employed a graph theoretical framework to characterize topological properties functional theta alpha frequency bands during tasks. Twenty-eight subjects performed visual n-back tasks two difficulty levels, i.e., 0-back...
Abstract Background Anxious depression is one of the common subtypes major depressive disorder ( MDD ). Clinically, patients with anxious exhibit more severe symptoms than nonanxious depression. The aim present study was to explore and differing cortical subcortical structural changes between Methods Patients were placed into three groups: group high levels anxiety symptoms, n = 23), 22), healthy controls 43) that matched for age, sex, education level. All participants underwent T1‐weighted...
Impaired capacity for Theory of Mind (ToM) represents one the hallmark features behavioral variant frontotemporal dementia (bvFTD) and is suggested to underpin an array socioemotional disturbances characteristic this disorder. In contrast, while social processing typically remains intact in Alzheimer's disease (AD), cognitive loading tasks may adversely impact mentalizing performance AD. Here, we employed Frith-Happé animations as a dynamic on-line assessment with reduced incidental task...
Objective Increasing evidence suggests that cerebellar damage impacts on cognitive functions. Frontotemporal dementias (FTDs) are neurodegenerative brain conditions, primarily affecting the frontal and/or temporal lobe. Three main phenotypes recognized, each with a distinct clinical and profile: behavioral‐variant FTD (bvFTD), semantic dementia (SD), progressive nonfluent aphasia (PNFA). The severity of changes their relation to cognition in FTD, however, remain unclear. This study aimed...
Objective This study aims to explore the correlation between brain natriuretic peptide (BNP) levels and prognosis in patients suffering from aneurysmal subarachnoid hemorrhage (aSAH). Methods retrospective included diagnosed with (aSAH) at Beijing Tiantan Hospital January 2015 September 2021. Plasma BNP were measured upon admission log-transformed reduce skewness. Elevated was defined as lgBNP ≥1.79 (equivalent ≥62 pg./mL). The primary outcome poor prognosis, a modified Rankin Scale (mRS)...
Low skeletal muscle mass is an independent risk factor for increased mortality in patients with acute-on-chronic liver failure (ACLF). However, no study has evaluated the temporal changes during course of ACLF. Therefore, this aimed to investigate dynamic and their prognostic role A retrospective analysis was conducted on consecutive ACLF who underwent two or more abdominal computed tomography examinations within 90 days admission. The percentage change rates index at third lumbar vertebra...
Weak or absent virus-specific CD8+ T-cell responses to hepatitis B virus (HBV) infection are thought be responsible for persistent HBV infection. Previous studies have indicated that multiple inhibitory receptors, including lymphocyte activation gene-3 (LAG-3), can suppress the response in chronic viral This study aimed detect LAG-3 expression and investigate manner which immune is regulated balance strength of with extent liver injury The results showed levels were significantly higher T...
BACKGROUND Leukoaraiosis is characterized by white matter lesions (WMLs) on magnetic resonance imaging (MRI) and associated with cognitive impairment. The small-world network viewed as the optimal brain maximal efficiency in information processing. Patients impairment are thought to have disrupted networks. In this study, we compared attributes between controls (study participants without memory complaints) patients WMLs MATERIAL AND METHODS All study were prescreened using MRI...
Abstract Sarcopenia (low muscle mass, i.e., quantity) is associated with poor clinical outcomes in patients acute-on-chronic liver failure (ACLF). In this study, we aimed to illustrate the prognostic value of myosteatosis (muscle fat infiltration) for short-term mortality ACLF. We retrospectively enrolled consecutive ACLF between January 2019 and 2022. Computed tomography-based body composition analysis was performed at third lumbar vertebral level determine skeletal radiation attenuation....
Abstract INTRODUCTION Associations of cerebellar atrophy with specific neuropathologies in Alzheimer's disease and related dementias (ADRD) have not been systematically analyzed. This study examined gray matter volume across major pathological subtypes ADRD. METHODS Cerebellar was using voxel‐based morphometry 309 autopsy‐proven ADRD cases 80 healthy controls. included AD, mixed Lewy body AD (LBD‐AD), frontotemporal lobar degeneration (FTLD). Clinical function assessed the Dementia Rating...
We aimed to investigate the activity within and connectivity between resting state networks (RSNs) in healthy subjects patients with Alzheimer's disease (AD) or mild cognitive impairment (MCI). Magnetic resonance imaging (MRI) resting-state MRI were performed on diagnosed AD (n=18) MCI (n=16) matching demographic characteristics (age, sex, education level). Independent component analysis Granger causality (GCA) used during image postprocessing. calculated 'In + Out degree' for each RSN....
The aim of the study was to investigate difference resting-state default-mode network (DMN) between patients with leukoaraiosis (LA)-associated subcortical vascular cognitive impairment (SVCI) and control subjects, provide functional imaging evidence SVCI.All subjects (n = 58) were divided into two groups based on their clinical diagnosis: a LA-associated SVCI group 31, 14 males) 27, males). Demographic information MRI (rs-fMRI) data obtained. These assessed using Hamilton Anxiety Depression...