A5102798637- Celiac Disease Research and Management
- Down syndrome and intellectual disability research
- Respiratory viral infections research
- Diabetes and associated disorders
- Bacterial Infections and Vaccines
- Microscopic Colitis
- Pneumonia and Respiratory Infections
- Immunodeficiency and Autoimmune Disorders
- Viral gastroenteritis research and epidemiology
- Gastrointestinal disorders and treatments
- Vaccine Coverage and Hesitancy
- Cardiovascular Function and Risk Factors
- Inflammatory Bowel Disease
- Virology and Viral Diseases
- Neonatal Respiratory Health Research
- Viral Infections and Immunology Research
- Esophageal and GI Pathology
- Infant Nutrition and Health
- Foreign Body Medical Cases
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Galectins and Cancer Biology
- Biliary and Gastrointestinal Fistulas
- Cytomegalovirus and herpesvirus research
- Alcoholism and Thiamine Deficiency
- Neonatal and Maternal Infections
Bambino Gesù Children's Hospital
2016-2022
Istituti di Ricovero e Cura a Carattere Scientifico
2016-2022
Italian Society of Physiotherapy
2021
Meyer Children's Hospital
2019
University of Florence
2019
Policlinico Umberto I
2010
Sapienza University of Rome
2008-2010
This study was aimed at showing the safety, for young patients with celiac disease (CD), of sweet baked goods made wheat flour, which rendered gluten-free during sourdough fermentation.As shown by R5 antibody-based sandwich and competitive enzyme-linked immunosorbent assay (ELISA), selected lactobacilli fungal proteases, routinely used in bakeries, degraded gluten to <10 ppm fermentation. The resulting flour mainly a mixture water-/salt-soluble low-size peptides free amino acids. Gliadin...
Respiratory syncytial virus (RSV) is the main cause of hospitalization for bronchiolitis among infants. RSV classified into two subtypes, A and B, whose predominance alternates during different epidemic seasons. The clinical impact viral factors controversial many evidences suggest a critical role immune host response. Premature children are at highest risk severe infection. aim this study to identify subtypes circulating in last three seasons evaluate whether any them was associated with...
We aimed to evaluate the safety and immunogenicity of BNT162b2 vaccine in young people with Down syndrome (DS), compare their humoral immune response those healthy controls (HC). Individuals DS HC received vaccine. Longitudinal blood samples were collected on day vaccination, twenty-one days after first dose, seven second six months dose. Both local systemic adverse events reported by participants mild. Pain at injection site was most event, while fever event. Humoral responses showed a...
Individuals with Down syndrome (DS) are at increased risk for being overweight/obese, but the associated cardiometabolic (CR) is not clear. Cross-sectional anthropometric and clinical laboratory data from a multi-site, international cohort of individuals DS were analyzed to determine by reporting observed distributions biomarkers in overweight/obese throughout lifespan. Descriptive statistics regression analyses age categories determined distributive percentiles tested adiposity as predictor...
Objective and design Risk factors for severe measles are poorly investigated in high-income countries. The Italian Society Paediatric Infectious Diseases conducted a retrospective study children hospitalised from January 2016 to August 2017 investigate the risk outcome defined by presence of long-lasting sequelae, need intensive care or death. Results Nineteen hospitals enrolled 249 (median age 14.5 months): 207 (83%) developed complication 3 (1%) died. Neutropaenia was more commonly...
The life expectancy of people with Down syndrome (DS) has significantly increased in the last decades. We describe congenital malformations and main comorbidities a cohort children young DS analyse their differences according to age gender groups.This retrospective cross-sectional study was conducted at centre Bambino Gesù Children's Hospital Rome (Italy). period for reviewing all electronic health records ran from July 2016 September 2017. collected data on clinical conditions compared them...
Children with Down syndrome (DS) show a high susceptibility to recurrent infections (RI), caused by immune defects and abnormalities of the airways. Our goal was investigate effects Pidotimod on RI prevention in children DS, comparing clinical parameters before (T0) after (T1) treatment Pidotimod.
Post-Infectious Neurological Syndromes (PINS) are heterogeneous neurological disorders with post or para-infectious onset. PINS diagnosis is complex, mainly related to the absence of any recognized guidelines and a univocal definition.To elaborate diagnostic guide for PINS.We retrospectively analysed patients younger than 14 years old admitted Bambino Gesù Children's Hospital in Rome from December 2005 March 2018. Scientific literature using PubMed as research platform was analysed: key...
The occurrence of hospital‐acquired acute gastroenteritis (AGE) is a major concern for public health. RotavirusA (RVA) and norovirus (NoV) are common causes viral AGE in the pediatric population, their role nosocomial infections has been proven, remaining poorly investigated. To investigate RVA NoV AGE, 55 stool samples from children with were collected between May 2014 2015. evaluate virus spreading routes, 51 environmental swabs staff patients’ rooms. Stools tested both RNA by...
Pertussis continues to be a common worldwide infection in pediatric and adult populations.We aimed study epidemiological clinical characteristics of infants children admitted for pertussis tertiary-care hospital investigate the risk factors intensive care unit (PICU) admission.With retrospective study, we analyzed all medical reports patients Bambino Gesù Children's Hospital Rome from January 2011 December 2018 with diagnosis pertussis.We examined 195 patients. The majority hospitalized...
BACKGROUND: Symptomatic Bartonella henselae infection is considered rare in Europe. Cat fleas transmit the microorganism between cats, but their role transmission of B. to humans has not been defined. The aim our study was perform a retrospective detected cases at Hospital.METHODS: We retrospectively analyzed data all children showing lymphadenopathy and 4-fold increase specific IgM for over period from June 2010 May 2015. therefore examined clinical data, laboratory exams order achieve...
Varicella is an acute infectious disease common during childhood. It has mostly uncomplicated course in early Neverthless, it may result severe complications, especially particular age groups and clinical conditions. Down Syndrome represents a risk factor for developing because of the frequent comorbidities their immunodeficiency. A 2-year-old white Caucasian female affected by was referred to our hospital cardiac arrest varicella disease. After cardiopulmonary resuscitation stabilization,...