- Antifungal resistance and susceptibility
- Antimicrobial Resistance in Staphylococcus
- Infective Endocarditis Diagnosis and Management
- Fungal Infections and Studies
- Streptococcal Infections and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Clostridium difficile and Clostridium perfringens research
- Antibiotics Pharmacokinetics and Efficacy
- Immune Response and Inflammation
- Neurological disorders and treatments
- Microbial Metabolism and Applications
- Drug Transport and Resistance Mechanisms
- Antimicrobial Peptides and Activities
- Bacterial Identification and Susceptibility Testing
- Orthopedic Infections and Treatments
- Infectious Aortic and Vascular Conditions
- Lysosomal Storage Disorders Research
- Hepatitis Viruses Studies and Epidemiology
- Escherichia coli research studies
- Adrenal Hormones and Disorders
- Pathogenesis and Treatment of Hiccups
- Historical Medical Research and Treatments
- Mycobacterium research and diagnosis
- Advanced X-ray and CT Imaging
- Intestinal and Peritoneal Adhesions
Justus-Liebig-Universität Gießen
2016-2025
Emory University
2024
The Ohio State University Wexner Medical Center
2024
Nottingham University Hospitals NHS Trust
2014
Siemens (Germany)
2001
Ruhr University Bochum
1998-2001
TU Dortmund University
2001
Vanderbilt University
1963-1974
United States Public Health Service
1970
Vanderbilt University Medical Center
1970
The nomenclature of hepatitis E virus (HEV) subtypes is inconsistent and makes comparison different studies problematic. We have provided a table proposed complete genome reference sequences for each subtype. criteria subtype assignment vary between genotypes methodologies, so conservative pragmatic approach has been favoured. Updates to this will be posted on the International Committee Taxonomy Viruses website (http://talk.ictvonline.org/r.ashx?C). use common facilitate communication...
A retrospective analysis of 218 patients with gram-negative rod bacteremia was made in order to evaluate factors affecting survival these patients. In comparable underlying disease, no significant increase mortality found be associated race, sex, hospital service, level leukocyte count, hospital-acquired infection, or the portal entry infection. Factors an increased from were shock, azotemia,<i>Pseu-</i><i>domonas</i>bacteremia, and low normal temperature during bacteremia. Appropriate...
PURPOSE: To determine the value of perfusion computed tomography (CT) in a clinical study patients with stroke and compare results single photon emission CT (SPECT) findings. MATERIALS AND METHODS: Perfusion was performed within 6 hours symptom onset 32 possible stroke. Cerebral blood volume (CBV), cerebral flow (CBF), time to peak contrast material enhancement were calculated on basis results. SPECT also subgroup 18 patients. findings compared lesion-by-lesion analysis. follow-up magnetic...
Background and Purpose —Besides the delineation of hypoperfused brain tissue, characterization ischemia with respect to severity is major clinical relevance, because degree hypoperfusion most critical factor in determining whether an ischemic lesion becomes infarct or represents viable tissue. CT perfusion imaging yields a set related parameters which might be useful describe hemodynamic status brain. Our objective was determine measurements relative cerebral blood flow (rCBF), volume...
A prospective study of 72 patients undergoing cardiovascular surgery showed that postoperative infections occurred in 20 - three after 31 nonbypass and 17 41 cardiopulmonary bypass procedures. Postoperative fever leukocytic response did not help to identify the presence infection, but infected tended have lower white-cell counts more juvenile polymorphonuclear leukocytes. Prophylactic antibiotic regimens consisting placebo, penicillin-streptomycin or oxacillin were administered a...
Abstract In three patients with chronic meningitis and repeatedly negative cultures cryptococcal antigen was detected in the cerebrospinal fluid by latex agglutination test. The diagnosis of cr...
A PROTRACTED epidemic of 21 postoperative infections due to M-nontypable, Group betahemolytic streptococci ceased after the implicated source, an anesthesiologist, was found be anal carrier large numbers streptococci. This is second such outbreak reported and raises possibility that dissemination from source more common currently suspected.The OutbreakNine wound caused by Croup occurred during three weeks in August, 1968, among general surgical, orthopedic gynecologic patients (Fig. 1). The...
The first marine pestivirus, Phocoena pestivirus (PhoPeV), isolated from harbor porpoise, has been recently described. To further characterize this unique its host cell tropism and growth kinetics were determined in different lines. In addition, the interaction of PhoPeV with innate immunity porcine epithelial cells role selected cellular factors involved viral entry RNA replication investigated comparison to closely distantly related pestiviruses. While Bungowannah (BuPV), a PhoPeV,...
BACTERIAL endocarditis due to penicillin-sensitive streptococci has generally responded satisfactorily antimicrobial therapy. In contrast, resulting from penicillin-resistant streptococci, usually of the enterococcal group, continued cause significant therapeutic problems.Enterococci produce 5 15 per cent all cases bacterial endocarditis, and this incidence may be increasing.1 These organisms, which are relatively resistant penicillin, alpha, beta or gamma hemolysis. For reason they...
BACTERIAL interference has been successful in curtailing epidemics of staphylococcal disease the nursery.1 2 3 4 Implantation a relatively nonpathogenic strain Staphylococcus aureus on nasal mucosa and umbilical stumps newborn infants prevented colonization with epidemic strains, thus interrupting their transmission from infant to infant. A Staph. designated 502A employed these studies. Persistent carriage pathogenic staphylococci adults also interrupted by implantation after antibiotic...
THE management of chronic renal failure by intermittent hemodialysis entails a definite risk bacteremic infection.1 , 2 However, an association bacterial endocarditis with periodic has not previously been stressed. The occurrence two cases among 47 patients participating in intermittent-hemodialysis program prompts the present report.Case 1. A 32-year-old man progressive symptoms uremia from glomerulonephritis was begun on biweekly through surgically created subcutaneous arteriovenous shunt....
Candida albicans injected intravenously into rabbits were rapidly cleared from the bloodstream. Organisms a peripheral vein predominantly by lungs; organisms mesenteric largely liver. The isolated, perfused rabbit liver avidly candida buffer perfusate, but clearance was enhanced when suspended in heated normal serum and most complete fresh used as perfusate.
DRUTZ, DAVID J.; SCHAFFNER, WILLIAM; HILLMAN, J. KOENIG, M. GLENN Author Information
THE current treatment of subacute bacterial endocarditis requires the intramuscular administration large amounts penicillin. Although this route is generally well tolerated, pain and inflammation at local sites injection can become a significant problem in management certain patients. Because low unpredictable serum levels attained after oral penicillin G, effective therapy has not previously been available.Recent studies on phenoxymethyl (penicillin V) have suggested that agent may...
Case Studies1 January 1966Disseminated Mycobacteriosis Caused by Battey Type MycobacteriaM. GLENN KOENIG, M.D., ROBERT D. COLLINS, M. HEYSSEL, M.D.M. M.D.Search for more papers this author, authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-64-1-145 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn the last decade, disease produced mycobacteria other than Mycobacterium...
Antitoxic and antibacterial immunity have been clearly differentiated in the experimental mouse infection produced by diffuse colonial variant of Smith strain Staphylococcus aureus. Immunization with crude toxoid protected mice from otherwise lethal doses alpha hemolysin, but did not alter mortality following intraperitoneal living staphylococci. Conversely, animals immunized heat killed vaccines were readily culture supernates containing strikingly fatal viable Protection was directly...
The dynamics of "reticuloendothelial blockade" were studied in living rabbits and isolated, perfused rabbit livers utilizing gelatin as a blockading agent Au(198) stabilized tracer. Employing the above experimental model, following observations made. (a) RES blockade was specific dependent on surface properties particle under study. (b) not caused by saturation hepatic removal mechanisms. (c) depletion demonstrable serum opsonins. (d) appeared to correlate with high circulating levels agent,...