A5048225042- Genomics and Chromatin Dynamics
- Protein Degradation and Inhibitors
- Nuclear Structure and Function
- RNA Research and Splicing
- Histone Deacetylase Inhibitors Research
- RNA regulation and disease
- CRISPR and Genetic Engineering
- Epigenetics and DNA Methylation
- Genetics and Neurodevelopmental Disorders
- Genetic Associations and Epidemiology
- Congenital heart defects research
- Gene expression and cancer classification
- Chromatin Remodeling and Cancer
- Tissue Engineering and Regenerative Medicine
- Healthcare Systems and Reforms
- Historical Economic and Social Studies
- Photochromic and Fluorescence Chemistry
- Click Chemistry and Applications
University of Pennsylvania
2020-2024
Cardiovascular Institute of the South
2024
Drexel University
2017-2019
Association of chromatin with lamin proteins at the nuclear periphery has emerged as a potential mechanism to coordinate cell type-specific gene expression and maintain cellular identity via silencing. Unlike many histone modifications chromatin-associated proteins, lamina-associated domains (LADs) are mapped genome-wide in relatively few genetically normal human types, which limits our understanding role peripheral plays development disease.
Abstract Association of chromatin with lamin proteins at the nuclear periphery has emerged as a potential mechanism to coordinate cell type-specific gene expression and maintain cellular identity via silencing. Unlike many histone modifications chromatin-associated proteins, lamin-associated domains (LADs) have yet be mapped genome-wide in diverse panel human types, which limited our understanding role peripheral plays development disease. To address this gap, we LAMIN B1 (LB1) across twelve...