- Liver Disease Diagnosis and Treatment
- Cytokine Signaling Pathways and Interactions
- Cardiac electrophysiology and arrhythmias
- Coronary Interventions and Diagnostics
- Ureteral procedures and complications
- Bioactive Compounds and Antitumor Agents
- Animal Virus Infections Studies
- Preterm Birth and Chorioamnionitis
- Cardiac Arrhythmias and Treatments
- Phytochemical and Pharmacological Studies
- Cervical Cancer and HPV Research
- Fuel Cells and Related Materials
- Reconstructive Facial Surgery Techniques
- Acute Myocardial Infarction Research
- Pomegranate: compositions and health benefits
- Systemic Lupus Erythematosus Research
- Cleft Lip and Palate Research
- Banana Cultivation and Research
- Estrogen and related hormone effects
- S100 Proteins and Annexins
- Reconstructive Surgery and Microvascular Techniques
- Echinoderm biology and ecology
- Advanced Glycation End Products research
- Drug Transport and Resistance Mechanisms
- Pineapple and bromelain studies
Suez Canal University
2024
British University in Egypt
2017-2023
Egyptian Russian University
2023
Minia University
2014-2022
Sinai University
2022
Alexandria University
2021
The nuclear receptor, farnesoid X receptor (FXR), has been recently considered as a tumor suppressor in HCC. IL-6/Janus kinase 2 (Jak-2)/signal transducer and activator of transcription 3 (STAT3) pathway implicated key player many cancer types. This study aimed at investigating the potential effect FXR agonist, obeticholic acid (OCA), on HCC involvement IL-6/STAT3 pathway. regulation STAT3 by its main feedback inhibitor target gene, cytokine signaling (SOCS3), triggered OCA was also...
Hepatocellular carcinoma (HCC) is one of the most common cancers reported worldwide with poor morbidity and high mortality rates. HCC a very vascular solid tumour as angiogenesis not only key driver for progression but also an exciting therapeutic target. Our research investigated use fucoidan, sulfated polysaccharide readily abundant in edible seaweeds commonly consumed Asian diet due to their extensive health benefits. Fucoidan was possess strong anti-cancer activity, its anti-angiogenic...
IntroductionSystemic lupus erythematosus (SLE) is a chronic, inflammatory, multiorgan, systemic autoimmune disease. It characterized by the high production of autoantibodies against nuclear compounds. TLRs (toll-like receptors 7/9) are pattern-recognition that recognize nucleic acids and induce proinflammatory responses activating NF-kB producing type I interferon, which play role in eliciting innate/adaptive immune developing chronic inflammation. TLR7 TLR9 single nucleotide polymorphisms...
Atrial fibrillation (AF) is a common, sustained tachyarrhythmia, associated with an increased risk of mortality and thromboembolic events. We performed this meta-analysis to compare the clinical efficacy rate rhythm control strategies in patients AF framework. A comprehensive search PubMed, OVID, Cochrane-CENTRAL, EMBASE, Scopus, Web Science was conducted, using relevant keywords. Dichotomous data on other events were extracted pooled as ratios (RRs), their 95% confidence-interval (CI),...
Lip and cheek adhesion to the opposing alveolus with complete or partial loss of vestibular dimension represents a challenging problem for reconstruction. It usually occurs due primary inadequate soft tissue repair following complicated trauma cases, burns, lesions oral cavity. Surgical removal scar creation new vestibule is by readhesion between connective surfaces. Skin grafts acellular dermal matrix represent most dominant modalities used treat deficient dimensions, but they are difficult...
Pancreatic cancer is a fatal tumor with 5-year survival rate below 10%. commonly diagnosed late, distant metastases. Thus, surgical cures are rare. First-line surgery often followed by adjuvant chemotherapy. The development of non-surgical pancreatic treatments very urgent. However, therapeutic resistance continues to affect therapy and prognosis. This requires detailed understanding processes. Additionally, novel methods must be actively investigated as treatments. treatment natural...
There are a lot of ceftriaxone sodium generics in the Egyptian market with huge variation prices, this raises tremendous question mark, does difference prices reflect potency?So, we made small-scale experiment to test potencies using antibiotic agar diffusion method similar assay its graphical and mathematical calculations.This was form comparative study ten against standard strain
Pomegranate (Punica granatum L.) is a fruit that widely consumed as fresh and juice.The use of pomegranate dates from ancient times literature about its therapeutic qualities has echoed throughout the ages.Several in vitro vivo studies have shown how this acts antioxidant, antidiabetic, hypolipidemic shows antibacterial, antiparasitic antifungal, antiinflammatory, antiviral, anti-carcinogenic activities.The also potentiates cardiovascular oral health.These beneficial physiological effects...
Background S100P, a binder of receptors for advanced-glycation end products, is an established biomarker many types cancer. However, data regarding its role in diabetes and diabetic peripheral neuropathy (DPN) are unclear. Aim The aim this work was to study the relationship between serum S100P DPN patients with type-2 mellitus (T2DM). Participants methods This cross-sectional included total 90 subjects divided into three groups: 30 T2DM complicated (group A), without B), as healthy-control...