A5050754442- HIV/AIDS Research and Interventions
- Adolescent Sexual and Reproductive Health
- HIV, Drug Use, Sexual Risk
- HIV/AIDS Impact and Responses
- Poverty, Education, and Child Welfare
- HIV Research and Treatment
- Food Security and Health in Diverse Populations
- Adolescent and Pediatric Healthcare
- Family Support in Illness
- COVID-19 and Mental Health
- Pneumocystis jirovecii pneumonia detection and treatment
- Tuberculosis Research and Epidemiology
- Global Maternal and Child Health
- Health disparities and outcomes
- Resilience and Mental Health
- Diagnosis and treatment of tuberculosis
- Psychological Well-being and Life Satisfaction
- Urban Agriculture and Sustainability
- Vaccine Coverage and Hesitancy
- HIV/AIDS drug development and treatment
- COVID-19 Pandemic Impacts
- Hepatitis B Virus Studies
- Mycobacterium research and diagnosis
- Homelessness and Social Issues
- Health, psychology, and well-being
South African Medical Research Council
2015-2024
Stellenbosch University
2023
University of Cape Town
2010-2023
Faculty of Public Health
2020
London School of Hygiene & Tropical Medicine
2020
University of the Witwatersrand
2013-2016
Desmond Tutu HIV Foundation
2011-2014
Zero to Three
2014
Médecins Sans Frontières
2012
South African Tuberculosis Vaccine Initiative
2010
Abstract Background In contexts where poverty and mental health stressors already interact to negatively impact the most vulnerable populations, COVID-19 is likely have worsened these impacts. Before pandemic, adolescent girls young women (AGYW) in South Africa faced intersecting vulnerabilities. It critical understand how additional challenges brought on by intersected with existing vulnerabilities risks AGYW faced, particularly given intersections between psychological distress increased...
The linkage and barriers of to facility-based HIV care from a mobile testing unit have not previously been described.A stratified random sample (N = 192) was drawn all eligible, newly diagnosed, HIV-infected individuals with laboratory CD4 count result on between August 2008 December 2009. All counts ≤350 cells per microliter 30% >350 were sampled. Linkage assessed during April June 2010 in those who received their result. A participant accessed at least once after regarded as having linked...
BackgroundHIV counseling and testing may serve as an entry point for non-communicable disease screening. ObjectivesTo determine the yield of newly-diagnosed HIV, tuberculosis (TB) symptoms, diabetes hypertension, to assess CD4 count testing, linkage care well correlates barriers from a mobile unit. MethodsA unit provided screening TB hypertension in Cape Town, South Africa between March 2010 September 2011. The cases these conditions was measured clients were followed-up January November...
Katharina Kranzer and colleagues investigate the operational characteristics of an active tuberculosis case-finding service linked to a mobile HIV testing unit that operates in underserviced areas Cape Town, South Africa.
Background Mobile HIV screening may facilitate early diagnosis. Our objective was to examine the cost-effectiveness of adding a mobile unit current medical facility-based testing in Cape Town, South Africa. Methods and Findings We used Cost Effectiveness Preventing AIDS Complications International (CEPAC-I) computer simulation model evaluate two strategies Town: 1) (the standard care) 2) addition HIV-testing intervention same community. Baseline input parameters were derived from Town-based...
Daily oral pre-exposure prophylaxis (PrEP) is highly efficacious for HIV prevention. Adolescent girls and young women (AGYW) have been prioritised PrEP delivery in South Africa. A combination prevention intervention providing integrated biomedical, behavioural structural interventions AGYW aged 15-24 twelve districts Africa characterised by high prevalence, was implemented 2019-2022. We conducted qualitative interviews to explore implementation experiences with 38 individuals involved the of...
Gender related vulnerabilities and inequalities place female learners at high risk of school disengagement due to COVID-19 disruptions. Understanding the impacts closures educational disruptions on in South Africa is critical inform appropriate, gender-sensitive policies, programs, mitigate further exacerbation inequalities. We examined effects that lockdowns have had experiences adolescent girls young women (AGYW) aged 15–24, six districts characterized by rates HIV, teenage pregnancy...
<ns3:p>In South Africa, after two decades of national femicide surveillance, we know comparatively little about what places women who experience intimate partner violence (IPV) at risk femicide. Further have not mapped the multi-generational health, social and economic impact severe IPV on subjected to it, their children, nor consequences help-seeking, described helps, STET recovery trajectories. This study aims deepen understanding factors for impacts families, including resilience...
The World Health Organisation's (WHO) key population-based strategy for ending the human immunodeficiency virus (HIV) epidemic is universal HIV test and treat (UTT) along with pre-exposure prophylaxis (PrEP), post-exposure (PEP). Despite successful scale-up of UTT in sub-Saharan Africa (SSA), quality life (QoL) people living (PLHIV) remains sub-optimal. Poor QoL PLHIV may threaten UNAIDS 95-95-95 programme targets. Monitoring has become a focus research among other outcomes so as to...
Adolescents experience disproportionately high rates of poor ART outcomes compared to adults despite prolonged use antiretroviral therapy in Southern African treatment programs, presenting a significant challenge national attempts meet the UNAIDS 90-90-90 targets for 2020. This cohort study among adolescents aged 12–20 years accessing care at two urban public-sector clinics Johannesburg between September and November 2013 aimed identify factors potentially associated with attendance clinic...
Objective The aim of the study was to compare yields newly diagnosed cases HIV infection and advanced immunodeficiency between individuals attending a mobile counselling testing (HCT) service as participants in population‐based seroprevalence survey those accessing same volunteers for routine testing. Methods conducted peri‐urban township within Cape Metropolitan Region, South Africa. Survey (recruited testers) were randomly selected, visited at home invited attend HCT service. They received...
Young people in sub-Saharan Africa encounter health and livelihood challenges which may compromise their wellbeing. Understanding how young people's wellbeing is defined could strengthen policies. We investigated perceptions experiences of wellbeing, whether these aligned with Ryff's psychological (PWB) model. Data were collected between January-August 2018 through focus-group discussions (n = 12) in-depth interviews 16) living without HIV, selected purposively from South African healthcare...
Timely linkage to antiretroviral therapy (ART) care is critical for reducing HIV-related morbidity, mortality and transmission. Studies investigating interventions improve to, retention in, pre-ART in sub-Saharan Africa were reviewed. Certain used overcome economic barriers ART-patients (i.e. integration of services, medical food incentives, intensified counselling peer support) have also shown favourable results the period. A combined package found be effective ART period might attrition...
Background. Health service coverage cascades measure the proportion of a population in need that experienced positive health outcome from service, and enable tracking progress achieving universal inequities care coverage. Objectives. To investigate HIV among HIV-positive adolescent girls young women (AGYW) living six South African districts, compare by age socioeconomic status (SES), other associated factors including participation combination prevention intervention. Methods. The HERStory...
Abstract Background Exposure to green spaces has been suggested improve mental health and may reduce the risk of depression. However, there is generally limited evidence on association between depression originating from low-and middle-income countries Africa in particular. Here, we investigate proximity public depressive symptoms among residents Gauteng Province, South Africa. Methods We used data 2017/2018 quality life survey. included all individuals aged 18 years or older residing nine...