Krzysztof Łukaszuk

ORCID: 0000-0001-5996-6991
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About
Contact & Profiles
Research Areas
  • Reproductive Biology and Fertility
  • Ovarian function and disorders
  • Assisted Reproductive Technology and Twin Pregnancy
  • Prenatal Screening and Diagnostics
  • Sperm and Testicular Function
  • Cervical Cancer and HPV Research
  • Endometriosis Research and Treatment
  • Reproductive System and Pregnancy
  • Uterine Myomas and Treatments
  • Endometrial and Cervical Cancer Treatments
  • SARS-CoV-2 and COVID-19 Research
  • Gynecological conditions and treatments
  • Reproductive Health and Technologies
  • Reproductive Physiology in Livestock
  • Ovarian cancer diagnosis and treatment
  • Genetic Syndromes and Imprinting
  • COVID-19 Clinical Research Studies
  • Sexual Differentiation and Disorders
  • Polish Legal and Social Issues
  • Genomic variations and chromosomal abnormalities
  • Family Support in Illness
  • Intellectual Property Rights and Media
  • Sports Performance and Training
  • Molecular Biology Techniques and Applications
  • Advanced Proteomics Techniques and Applications

Gdańsk Medical University
2015-2024

Institute of Technology and Life Sciences
2022

Medical University of Warsaw
2016-2021

Postgraduate School of Molecular Medicine
2015-2021

Aarhus University Hospital
2020

Sapienza University of Rome
2020

Copenhagen University Hospital
2020

Johns Hopkins University
2020

University of Copenhagen
2020

University of Warmia and Mazury in Olsztyn
2013-2014

Chromosome errors, or aneuploidy, affect an exceptionally high number of human conceptions, causing pregnancy loss and congenital disorders. Here, we have followed chromosome segregation in oocytes from females aged 9 to 43 years report that aneuploidy follows a U-curve. Specific error types show different age dependencies, providing quantitative explanation for the Whole-chromosome nondisjunction events are preferentially associated with increased young girls, whereas centromeric more...

10.1126/science.aav7321 article EN Science 2019-09-26

The aim of the study was to create a predictive model blastocyst development based on morphokinetic parameters time-lapse embryoscope monitoring.Time-lapse recordings 432 embryos (obtained from 77 patients), monitored in Embryoscope, were involved study. Patients underwent vitro fertilization according standard procedure between June 2012 and April 2013. A retrospective analysis features, focused duration time Intracytoplasmic Sperm Injection (ICSI) consecutive embryo division for 2, 3, 4 5...

10.1007/s10815-015-0440-3 article EN cc-by Journal of Assisted Reproduction and Genetics 2015-02-17

The aim of the study was to assess granulocyte colony-stimulating factor (G-CSF) effects on unresponsive thin (<7 mm) endometrium in women undergoing vitro fertilization (IVF). We included thirty-seven subjects who had day triggering ovulation. These patients also failed achieve an adequate endometrial thickness at least one their previous IVF cycles. In all time infusion G-CSF, 6,74 ± 1,75 mm, and, after infusion, it increased significantly 8,42 1,73 mm. When we divided group into two...

10.1155/2014/913235 article EN cc-by BioMed Research International 2014-01-01

Background: The introduction of the vaccination against SARS-CoV-2 infection creates need for precise tools quality control procedures, detection poor humoral response, and estimation achieved protection disease. Thus, study aimed to compare results anti-SARS-CoV-2 tests evaluate application WHO standard unitage (the binding antibody units; BAU/mL) a measurement response vaccination. Methods: Patients undergoing with Pfizer/BioNTech BNT162b2 (BNT162b2) (n = 79), referred prior 21 days after...

10.3390/vaccines9080840 article EN cc-by Vaccines 2021-07-31

The aim of the study was to assess granulocyte-colony stimulating factor (G-CSF) effect on unresponsive thin (<7 mm) endometrium in women undergoing frozen-thawed embryo transfer at blastocyst stage. A total 62 with were included study, which, 29 received a G-CSF infusion and 33 who opted out served as controls. Patients both groups had similar endometrial thickness time initial evaluation: 6.50 mm (5.50-6.80) 6.40 (5.50-7.0) control group. However, after increased significantly group...

10.1080/19396368.2016.1251505 article EN Systems Biology in Reproductive Medicine 2016-11-22

Can anti-Müllerian hormone (AMH) automated immunoassays (Elecsys® and Access) be used interchangeably as a companion diagnostic for individualisation of follitropin delta dosing? The Access assay gives systematically higher AMH values than the Elecsys® which results in over 29% women being misclassified to different dose. Follitropin is first gonadotrophin licenced with diagnostic, Roche Plus assay. Alternative assays including Beckman Coulter immunoassay are considered provide similar...

10.1093/humrep/dex219 article EN cc-by Human Reproduction 2017-05-22

Human follicular fluid (hFF) is a natural environment of oocyte maturation, and some components hFF could be used to judge capability for fertilization further development. In our pilot small-scale study three samples from four donors (12 in total) were analyzed determine which proteins/peptides differentiate individual oocytes are patient-specific. Ultrafiltration was fractionate high-molecular-weight (HMW) proteome (>10 kDa) low-molecular-weight (LMW) peptidome (<10 fractions. HMW LMW...

10.1021/acs.jproteome.7b00366 article EN Journal of Proteome Research 2017-06-29

Uterine fibroids (UFs) are one of the most common pathologies female genital tract. The incidence UFs has been estimated at 25-80%. Tumor necrosis factor (TNF)-α is a cell-signaling protein involved in systemic inflammation and cytokines responsible for acute phase reaction. aim study was to evaluate impact clinically symptomatic on TNF-α serum levels. A total 149 Caucasian women were included: 85 patients admitted surgery due (n = 85; group) 64 age-matched UF-free controls 64)....

10.1177/2058738418779461 article EN cc-by-nc International Journal of Immunopathology and Pharmacology 2018-01-01
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