A5038860689- Astrophysics and Cosmic Phenomena
- Neutrino Physics Research
- Dark Matter and Cosmic Phenomena
- Radio Astronomy Observations and Technology
- Particle physics theoretical and experimental studies
- Osteoarthritis Treatment and Mechanisms
- Gamma-ray bursts and supernovae
- Lower Extremity Biomechanics and Pathologies
- Knee injuries and reconstruction techniques
- Advanced MRI Techniques and Applications
- Corporate Governance and Management
- Total Knee Arthroplasty Outcomes
- Particle Detector Development and Performance
- Pulsars and Gravitational Waves Research
- MRI in cancer diagnosis
- Bone and Joint Diseases
- Musculoskeletal synovial abnormalities and treatments
- Advanced Neuroimaging Techniques and Applications
- Radio Wave Propagation Studies
- Psychology, Coaching, and Therapy
- Hip disorders and treatments
- Orthopaedic implants and arthroplasty
- Shoulder Injury and Treatment
- Medical Imaging Techniques and Applications
- Atmospheric Ozone and Climate
Uppsala University
2020-2024
The University of Texas at Arlington
2021-2024
Lawrence Berkeley National Laboratory
2023-2024
Southern University and Agricultural and Mechanical College
2021-2024
Clark Atlanta University
2021-2024
University of Alaska Anchorage
2021-2024
Providence College
2021-2024
Friedrich-Alexander-Universität Erlangen-Nürnberg
2021-2023
Michigan State University
2021-2023
University of Nebraska–Lincoln
2023
This article presents the design of Radio Neutrino Observatory Greenland (RNO-G) and discusses its scientific prospects. Using an array radio sensors, RNO-G seeks to measure neutrinos above 10 PeV by exploiting Askaryan effect in neutrino-induced cascades ice. We discuss experimental considerations that drive RNO-G, present first measurements hardware is be deployed projected sensitivity instrument. will production-scale detector for in-ice neutrino signals.
Alterations of cartilage morphology and mechanical properties occur in osteoarthritis, but it is unclear whether similar changes also take place physiologically during aging, the absence disease. In this vivo study, we tested hypothesis that thinning knee joint occurs with aging elderly subjects display a different amount deformation than do young subjects.We evaluated 30 asymptomatic ages 50-78 years. Morphologic parameters for (mean maximum thickness, surface area) were computed from...
To examine the in vivo accuracy and precision of magnetic resonance imaging (MRI)-based assessment cartilage loss patients with severe osteoarthritis (OA) knee.High-resolution MRI images tibial were obtained 8 prior to total knee arthroplasty, using a water-excitation gradient-echo sequence (acquisition time 6 minutes 19 seconds; spatial resolution 1.2 x 0.31 mm3). The measurements repeated after joint repositioning. volume thickness computations was determined 3-dimensional reconstruction....
Abstract Independent component analysis (ICA) of functional magnetic resonance imaging (fMRI) time‐series reveals distinct coactivation patterns in the resting brain representing spatially coherent spontaneous fluctuations fMRI signal. Among these patterns, so‐called default‐mode network (DMN) has been attributed to ongoing mental activity during wakeful state. Studies suggest that many neuropsychiatric diseases disconnect areas belonging DMN. The potential use DMN as marker for individuals...
Abstract T 2 relaxation time is a promising MRI parameter for the detection of cartilage degeneration in osteoarthritis. However, accuracy and precision measured may be substantially impaired by low signal‐to‐noise ratio images available from clinical examinations. The purpose this work was to assess traditional fit methods (linear least‐squares regression nonlinear an exponential) two new noise‐corrected methods: exponential squared signal intensity exponential. Accuracy have been analyzed...
Abstract is a Monte Carlo framework designed to simulate ultra-high energy neutrino detectors that rely on the radio detection method. This method exploits emission generated in electromagnetic component of particle shower following interaction. simulates everything from interaction medium, subsequent Askaryan emission, propagation signal detector and finally response. as modern, modular Python-based framework, combining flexibility design with user-friendliness. It includes state-of-the-art...
The full optimization of the design and operation instruments whose functioning relies on interaction radiation with matter is a super-human task, due to large dimensionality space possible choices for geometry, detection technology, materials, data-acquisition, information-extraction techniques, interdependence related parameters. On other hand, massive potential gains in performance over standard, "experience-driven" layouts are principle within our reach if an objective function fully...
A noninvasive imaging technique for quantifying articular cartilage is needed diagnosis, monitoring, and therapy control in osteoarthritis. In this study the accuracy of three-dimensional volume thickness measurements knee with magnetic resonance was analyzed. Eight cadaveric specimens had sagittal a fat suppressed gradient echo sequence. After contrast agent injected, two computed tomography data sets were obtained, knees being repositioned between examinations. The determined, after...
MR diffusion tensor imaging (DTI) was used to analyze the microstructural properties of articular cartilage. Human patellar cartilage-on-bone samples were imaged at 9.4T using a diffusion-weighted SE sequence (12 gradient directions, resolution = 39 x 78 1500 microm(3)). Voxel-based maps mean diffusivity, fractional anisotropy (FA), and eigenvectors calculated. The diffusivity decreased from surface (1.45 10(-3) mm(2)/s) tide mark (0.68 mm(2)/s). FA low (0.04-0.28) had local maxima near in...
Abstract Objective It is currently unknown whether human cartilage properties change during short periods of partial load bearing. We used a post–ankle fracture model to explore changes in morphology occur the knee under conditions Methods The knees 20 patients with Weber type B and C fractures were examined using magnetic resonance imaging. first scan was obtained shortly (mean ± SD 3.2 3.0 days) after injury, second 7 weeks later 50.7 5.5 days). maximum thickness, volume, surface area)...
To evaluate the clinical feasibility of diffusion tensor imaging (DTI) kidney in volunteers and patients with renal diseases.Ten 22 (mean age, 56 +/- 14.3) masses artery stenosis underwent breath-hold coronal fat-saturated echo-planar DTI (as provided by manufacturer, 6 directions, weightings b = 0 300 s/mm2, repetition time 730 ms/echo 72 ms; 5 slices; slice thickness, mm; inplane resolution, 2.1 x mm2; acquisition time, 26 seconds) kidneys at 1.5 T (MAGNETOM Avanto, Siemens Medical...
To evaluate magnetic resonance (MR) T2 mapping for characterization of cartilage repair tissue following matrix-associated autologous transplantation (MACT).Fifteen patients were evaluated MACT using a 3T MR scanner. Patients categorized into 2 postoperative intervals: I: 3-13 months, II: 19-42 months. Mean relaxation times calculated from multiple spin-echo sequence determined in regions interest (MACT and normal hyaline cartilage) line profiles through the control sites acquired.Mean...
Purpose: To clinically evaluate MRI of the knee using a highly resolved isotropic fat-saturated (fs) proton-density weighted 3D-TSE-sequence (SPACE) at 3T. Materials and Methods: Imaging was performed on 3T-scanner (Magnetom TRIO). For technical evaluation, sagittally orientated SPACE-datasets (repetition-time [TR], 1200 milliseconds/[TE], 30 milliseconds/voxel-size, 0.5 mm3/acquisition time, 10:35 minutes) were acquired from dominant 10 healthy volunteers. In 3 major anatomic planes, 0.5,...
The purpose of this study was to evaluate the feasibility diffusion tensor imaging kidney at a field strength 3T. We assessed fractional anisotropy (FA) and apparent coefficients (ADC) various acquisition protocols determined reproducibility these measurements. FA, ADC, signal-to-noise ratios (SNR), contrast-to-noise (CNR) were compared with those acquired 1.5T.Ten healthy volunteers examined respiratory-triggered echo-planar sequence (TR: 1800 ms, TE: 58 b = 0, 300 s/mm(2)) on 3-Tesla...
To investigate technical feasibility, test-retest reproducibility, and the ability to differentiate healthy subjects from with osteoarthritis (OA) diffusion-tensor (DT) imaging parameters T2 relaxation time.This study was approved by institutional review board HIPAA compliant. All provided written informed consent. DT (resolution=0.6×0.6×2 mm) of patellar cartilage were measured at 7.0 T in 16 volunteers 10 patients OA subtle inhomogeneous signal intensity but no signs erosion clinical...
The quantification of cerebral blood flow (CBF), volume (CBV), and blood-brain barrier permeability in scattered lesions the brain is a methodological challenge. We aimed to investigate feasibility 3D T1-weighted dynamic contrast-enhanced (DCE) MRI acquisition combination with 2-compartment modeling approach for CBF, CBV surface area product (PS) lesions, normal-appearing white matter (NAWM) patients multiple sclerosis (MS).In all, 19 MS (mean age 35 years, 12 female) underwent DCE-MRI...
As a crucial security problem, anti-spoofing in biometrics, and particularly for the face modality, has achieved great progress recent years. Still, new threats arrive inform of better, more realistic sophisticated spoofing attacks. The objective 2nd Competition on Counter Measures to 2D Face Spoofing Attacks is challenge researchers create counter measures effectively detecting variety submitted propositions are evaluated Replay-Attack database results presented this paper.
To assess the use of diffusion-tensor (DT) imaging articular cartilage to detect and grade early damage in human specimens with signs damage.This study was approved by institutional review board. Forty-three cartilage-on-bone samples drilled from 21 patellae were examined 17.6-T magnetic resonance (MR) a diffusion-weighted spin-echo sequence (spatial resolution, 50 × 100 800 μm). Subsequently, underwent histologic analysis safranin O staining. Cartilage on slides quantified Osteoarthritis...
The primary mission of the ARIANNA ultra-high energy neutrino telescope is to uncover astrophysical sources neutrinos with energies greater than $10^{16}\mathrm{eV}$. A pilot array, consisting seven stations located on surface Ross Ice Shelf in Antarctica, was commissioned November 2014. We report search for using data collected between 2014 and February 2019. straight-forward template matching analysis yielded no candidates, a signal efficiency 79%. find 90% confidence upper limit diffuse...
Tau neutrinos are the least studied particle in Standard Model. This whitepaper discusses current and expected upcoming status of tau neutrino physics with attention to broad experimental theoretical landscape spanning long-baseline, beam-dump, collider, astrophysical experiments. was prepared as a part NuTau2021 Workshop.