A5010669194- Vector-borne infectious diseases
- Viral Infections and Vectors
- Bartonella species infections research
- Mosquito-borne diseases and control
- Vector-Borne Animal Diseases
- Dermatological diseases and infestations
- Yersinia bacterium, plague, ectoparasites research
- Insect symbiosis and bacterial influences
- Zoonotic diseases and public health
- Parasitic Diseases Research and Treatment
- Insect and Pesticide Research
- Rabies epidemiology and control
- Bacterial Identification and Susceptibility Testing
- Genomics and Phylogenetic Studies
- Parasites and Host Interactions
- Parasite Biology and Host Interactions
- Leptospirosis research and findings
- Viral gastroenteritis research and epidemiology
- Trypanosoma species research and implications
- Research on Leishmaniasis Studies
- Virology and Viral Diseases
- Microbial infections and disease research
- Amphibian and Reptile Biology
- Plant Pathogens and Fungal Diseases
- Streptococcal Infections and Treatments
Institut de Recherche pour le Développement
2016-2025
Méditerranée Infection Foundation
2016-2025
Inserm
2012-2025
Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes
2010-2025
Cheikh Anta Diop University
2013-2025
Aix-Marseille Université
2016-2025
Délégation Provence et Corse
2024
Assistance Publique Hôpitaux de Marseille
2018-2022
Université Jean Moulin Lyon III
2011-2020
Institut de Recherche pour le Développement
2020
Background Q fever is a worldwide zoonotic disease caused by Coxiella burnetii. Epidemiologically, animals are considered reservoirs and humans incidental hosts. Methodology/Principal Findings We investigated in rural Senegal. Human samples (e.g., sera, saliva, breast milk, feces) were screened the generally healthy population of two villages Sine-Saloum region. Ticks collected four regions. Seroprevalence was studied immunofluorescence, all other tested qPCR systems for detection C....
We describe the characterization of a novel Rickettsia species cultivated from Dermacentor ticks collected in Russia and France, for which we propose name raoultii sp. nov. Using multigene sequencing, demonstrated that five rickettsial isolates silvarum, reticulatus, marginatus nuttalli were classified within this spotted fever rickettsia species. This also exhibited serotype distinct previously described The type strain is Khabarovsk(T) (=CSUR R3(T) =ATCC VR-1596(T)).
During November 2008-July 2009, we investigated the origin of unknown fever in Senegalese patients with a negative malaria test result, focusing on potential rickettsial infection. Using molecular tools, found evidence for Rickettsia felis-associated illness initial days infection febrile without malaria.
Rickettsioses are one of the most important causes systemic febrile illness among travelers from developed countries, but little is known about their incidence in indigenous populations, especially West Africa.Overall seroprevalence evaluated by immunofluorescence using six rickettsial antigens (spotted fever and typhus group) rural populations two villages Sine-Saloum region Senegal was found to be 21.4% 51% for spotted group rickettsiae Dielmo Ndiop villages, respectively. We investigated...
Detecting spirochetes remains challenging in cases of African tick-borne relapsing fever. Using real-time PCR specific for the 16S rRNA Borrelia gene, we found 27 (13%) 206 samples from febrile patients rural Senegal to be positive, whereas thick blood smear examinations conducted at dispensaries identified only 4 (2%) as positive.
Background In tropical Africa, where the spectrum of bacterial pathogens that cause fevers is poorly understood and molecular-based diagnostic laboratories are rare, time lag between test results patient care a critical point for treatment disease. Methodology/Principal Findings We implemented POC laboratory in rural Senegal to resolve care. During first year study (February 2011 January 2012), 440 blood specimens from febrile patients were collected Dielmo Ndiop villages. All samples...
Abstract This study aimed to compare the epidemiology of Rickettsia felis infection and malaria in France, North Africa, sub-Saharan Africa identify a common vector. Blood specimens from 3,122 febrile patients 500 nonfebrile persons were analyzed for R. Plasmodium spp. We observed significant linear trend (p<0.0001) increasing risk infection. The risks lowest Tunisia, Algeria (1%), highest rural Senegal (15%). Co-infections with occurrences relapses or reinfections identified. demonstrates...
Rodents are known to be reservoir hosts for at least 60 zoonotic diseases and play an important role in their transmission spread different ways. We sampled rodent communities within around human settlements Northern Senegal, area subjected major environmental transformations associated with global changes. Herein, we conducted epidemiological study on bacterial communities. One hundred seventy-one (171) invasive native rodents were captured, 50 from outdoor trapping sites 121 indoor...
Background Our study aimed to assess the presence of different pathogens in ticks collected two regions Côte d’Ivoire. Methodology/Principal Findings Real-time PCR and standard assays coupled sequencing were used. Three hundred seventy eight (378) (170 Amblyomma variegatum, 161 Rhipicepalus microplus, 3 Rhipicephalus senegalensis, 27 Hyalomma truncatum, 16 marginatum rufipes, 1 impressum) identified analyzed. We as pathogenic bacteria, Rickettsia africae Am. variegatum (90%), Rh. microplus...
There is a significant gap in our knowledge of the microbe–host relationship between urban and traditional rural populations. We conducted large-scale study to examine gut microbiota different lifestyles human Using high-throughput 16S ribosomal RNA gene amplicon sequencing, we tested French, Saudi, Senegalese, Nigerian Polynesian individuals as well living societies, including Amazonians from French Guiana, Congolese Pygmies, Saudi Bedouins Algerian Tuaregs. The settings clustered...
Abstract An acute tick-borne rickettsiosis caused by Rickettsia heilongjiangensis was diagnosed in 13 patients from the Russian Far East 2002. We amplified and sequenced four portions of three rickettsial genes patients' skin biopsy results blood samples showed that belong to R. heilongjiangensis, which recently isolated Dermacentor sylvarum ticks nearby regions China. This rickettsia, belonging subgroup japonica, previously suggested be pathogenic for humans on basis serologic findings....
Tick-borne diseases comprise a complex epidemiological and ecological network that connects the vectors, pathogens, group of host species. The aim this study was to identify bacteria from genus Rickettsia associated with ixodid ticks infesting camels cows in Egypt. Ticks were collected 6 different localities: Qina, Giza, Qalet El Nakhl, New Valley, Arish, Minufia, July October 2008. Species identified using PCR, followed by sequencing. gltA rOmpA genes used for initial detection spp. Further...
Abstract To determine the presence of Bartonella quintana in head and body lice from persons different locations Ethiopia, we used molecular methods. B. was found 19 (7%) genotype C 76 (18%) A lice. positively linked to altitude (p = 0.014).