Y Wang

ORCID: 0000-0001-6039-5380
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About
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Research Areas
  • Cancer, Hypoxia, and Metabolism
  • Glioma Diagnosis and Treatment
  • Dendrimers and Hyperbranched Polymers
  • Synthesis of Tetrazole Derivatives
  • Sarcoma Diagnosis and Treatment
  • Immune cells in cancer
  • Medicinal Plants and Neuroprotection
  • Hepatitis B Virus Studies
  • Nanoparticle-Based Drug Delivery
  • Heterotopic Ossification and Related Conditions
  • Mycobacterium research and diagnosis
  • Synthesis and Characterization of Heterocyclic Compounds
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Animal Virus Infections Studies
  • Health disparities and outcomes
  • Reproductive biology and impacts on aquatic species
  • Liver Disease Diagnosis and Treatment
  • Cancer Cells and Metastasis
  • Cholinesterase and Neurodegenerative Diseases
  • Medicinal Plant Pharmacodynamics Research
  • Alzheimer's disease research and treatments
  • Pharmacovigilance and Adverse Drug Reactions
  • Pharmaceutical studies and practices
  • interferon and immune responses
  • Biomedical Ethics and Regulation

Guangdong Medical College
2023-2024

Sun Yat-sen University
2013-2016

University of Strathclyde
2010

Background Metformin has the potential for treating numerous diseases, but there are still many unrecognized and unreported adverse events (AEs).

10.1080/17512433.2024.2306223 article EN Expert Review of Clinical Pharmacology 2024-01-25

Male infertility, age-related changes, and tumors have been increasingly studied in the field of male reproductive health due to emergence environmental stressors, declining fertility rates, aging populations. Numerous studies demonstrated that ERK1/2 signaling pathway plays a significant role reproduction. The is associated with several pathways has complex interplay influences spermatogenic microenvironment, sperm viability, gonadal axis regulation, as well resistance testicular tumors....

10.31083/j.fbl2901023 article EN cc-by Frontiers in Bioscience-Landmark 2024-01-18

Because of their potent regenerative and immunomodulatory properties, mesenchymal stem cells (MSCs) have promising therapeutic benefits in clinical treatment inflammatory infectious diseases. Recent studies suggest that many biological activities MSCs are largely determined by pattern recognition receptors (PRRs), such as Toll-like (TLRs). However, the role PRRs regulating survival remains unknown. In present study, we examined viability after stimulation distinct PRRs. Activation TLRs...

10.1038/cddis.2013.504 article EN cc-by Cell Death and Disease 2013-12-12

Alzheimer's disease (AD) is the most common neurodegenerative disease, severely reducing cognitive level and life quality of patients. Byu dMar 25 (BM25) has been proved to have a therapeutic effect on AD. However, pharmacological mechanism still unclear. Therefore, this study aims reveal potential BM25 affecting AD from perspective network pharmacology experimental validation.The active ingredients were obtained TCMSP database literature. Possible targets predicted using...

10.1021/acsomega.3c01683 article EN cc-by-nc-nd ACS Omega 2023-06-13

Background: Danxiong Huoxue tablets have been used clinically to prevent and treat Heterotopic Ossification (HO) after total hip arthroplasty, but its therapeutic mechanism is not clear. background: Tablets has heterotopic ossification Objectives: This study investigated the potential of action against HO using network pharmacology molecular docking methods. Methods: The TCMID SymMap databases existing literature were screen active ingredients targets tablets, obtained from Gene Cards,...

10.2174/0115748855341056240911101658 article EN Current Drug Therapy 2024-09-27

<h3>Objective</h3> Obesity and physical activity are associated with aspects of the environment where people live, but precise mechanisms these associations not well understood. Knowledge extent to which access opportunities for is socially patterned important inform policy. A few studies cities regions (mostly conducted outside UK) have found fewer resources in deprived areas, while others not. The aim this study was examine distribution facilities by area level deprivation Scotland,...

10.1136/jech.2010.120477.36 article EN Journal of Epidemiology & Community Health 2010-09-01
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