A5079598587- Cardiac, Anesthesia and Surgical Outcomes
- Aortic aneurysm repair treatments
- Vascular Procedures and Complications
- Venous Thromboembolism Diagnosis and Management
- Peripheral Artery Disease Management
- Aortic Disease and Treatment Approaches
- Antiplatelet Therapy and Cardiovascular Diseases
- Infectious Aortic and Vascular Conditions
- Cardiac and Coronary Surgery Techniques
- Atrial Fibrillation Management and Outcomes
- Cardiac Imaging and Diagnostics
- Cardiac Ischemia and Reperfusion
- Acute Ischemic Stroke Management
- Coronary Interventions and Diagnostics
- Diagnosis and Treatment of Venous Diseases
- Abdominal Surgery and Complications
- Vascular anomalies and interventions
- Hemodynamic Monitoring and Therapy
- Hip and Femur Fractures
- Diabetic Foot Ulcer Assessment and Management
- Acute Myocardial Infarction Research
- Soft tissue tumor case studies
- Abdominal vascular conditions and treatments
- Sarcoma Diagnosis and Treatment
- Tumors and Oncological Cases
Amsterdam University Medical Centers
2019-2024
Westfriesgasthuis
2012-2024
Reinier de Graaf Hospital
2021-2024
Vrije Universiteit Amsterdam
2023-2024
Refaja Ziekenhuis
2019-2023
Leiden University Medical Center
2018-2022
Dutch Institute for Clinical Auditing
2020-2022
Leiden University
2022
The Netherlands Cancer Institute
2022
University of Amsterdam
2019-2021
OBJECTIVE Conflicting evidence exists on the effects of hyperbaric oxygen therapy (HBOT) in treatment chronic ischemic leg ulcers. The aim this trial was to investigate whether additional HBOT would benefit patients with diabetes and RESEARCH DESIGN AND METHODS Patients an wound (n = 120) were randomized standard care (SC) without or (SC+HBOT). Primary outcomes limb salvage healing after 12 months, as well time healing. Other end points amputation-free survival (AFS) mortality. RESULTS Both...
ObjectiveInternational guidelines recommend supervised exercise therapy (SET) as primary treatment for all patients with intermittent claudication (IC), yet endovascular revascularisation (ER) might be more effective in iliac artery obstruction.MethodsThis was a multicentre RCT including IC caused by stenosis or occlusion (NCT01385774). Patients were allocated randomly to SET ER stratified maximum walking distance (MWD) and concomitant SFA disease. Primary endpoints MWD on treadmill (3.2...
To determine the safety and efficacy of treating abdominal aortic aneurysm (AAA) sacs with polyurethane shape memory polymer (SMP) devices during endovascular repair (EVAR), using a technique to fully treat target lumen after endograft placement (aortic flow volume minus volume). SMP self-expand in sac form porous scaffold that supports thrombosis throughout its structure.
Females are more prone to complications during non-cardiac arterial procedures (NCAPs) than males. The current study investigated the difference in effect of peri-procedural prophylactic heparin males and females, using activated clotting time (ACT). This was a retrospective analysis prospective multicentre cohort study.All patients undergoing elective NCAP ACT measurements between January 2016 March 2020 were included. Two dosage protocols used: weight based dosing 100 IU/kg (international...
In non-cardiac arterial procedures (NCAP), heparin is administered to prevent thromboembolic complications (ATEC). Heparin has a nonpredictable effect in the individual patient, also known as variation sensitivity. Various dosing protocols are use, but optimal dose currently still unknown. A standardized bolus of 5 000 IU most frequently used by vascular surgeons and interventional radiologists. The activated clotting time (ACT) an established method measure level anticoagulation, has, until...
The aim of this study was to develop a 48-h mortality risk score, which included morphology data, for patients with ruptured abdominal aortic aneurysm presenting an emergency department, and assess its predictive accuracy clinical effectiveness in triaging immediate repair, transfer or palliative care.Data from the IMPROVE (Immediate Management Patient With Ruptured Aneurysm: Open Versus Endovascular Repair) randomized trial were used score. Variables considered age, sex, haemodynamic...
Unfractionated heparin has an unpredictable effect in individual patient. The activated clotting time (ACT) can be used to measure the of patient and guide additional dosages. Previous cohort studies showed that a standardized bolus 5,000 IU during noncardiac arterial procedures (NCAP) does not lead adequate ACT vast majority patients. aim this study was investigate whether initial dose 100 IU/kg leads but safe ACT, from 200 300 s.In multicenter prospective study, 186 patients undergoing...
Purpose: To describe the successful endovascular treatment of 2 patients with type IIIb endoleak using Nellix EndoVascular Aneurysm Sealing (EVAS) System. Case Report: Two men aged 75 and 83 years presented several (8 3, respectively) after initial aneurysm repair. Dual endoprosthesis were deployed in stent-grafts, endobags filled polymer to seal defect eliminate endoleak. The perioperative periods uneventful. At up 6-month follow-up, no endoleaks detected, diameters unchanged, endografts...
ObjectiveRegular measurement of fibrinogen as dose guidance in catheter directed thrombolysis (CDT) for acute limb ischaemia (ALI) has recently been dropped from European guidelines based on inconsistent literature. This study aimed to determine whether low levels and high activated partial thromboplastin time (APTT) are associated with an increased major bleeding risk during CDT.MethodsAll consecutive patients treated CDT ALI two Dutch hospitals between January 2004 April 2021 were analysed...
Abstract The pathophysiology of aortic aneurysms (AA) is far from being understood. One reason for this lack understanding basic research constrained to fixated cells or isolated cell cultures, by which cell-to-cell and cell-to-matrix communications are missed. We present a new, in vitro method extended preservation wall sections study pathophysiological processes. Intraoperatively harvested, live specimens were cut into 150 μm cultured. Viability was quantified up 92 days using...