A5033822074- Intracranial Aneurysms: Treatment and Complications
- Moyamoya disease diagnosis and treatment
- Cerebrovascular and Carotid Artery Diseases
- Vascular Malformations Diagnosis and Treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebrovascular and genetic disorders
- Neurological Complications and Syndromes
- Acute Ischemic Stroke Management
- Neuroinflammation and Neurodegeneration Mechanisms
- Aortic aneurysm repair treatments
- Liver Disease Diagnosis and Treatment
- Stroke Rehabilitation and Recovery
- Microbial metabolism and enzyme function
- Toxic Organic Pollutants Impact
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Chronic Kidney Disease and Diabetes
- Mercury impact and mitigation studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Air Quality and Health Impacts
- Ferroptosis and cancer prognosis
- Retinal Diseases and Treatments
- Gestational Diabetes Research and Management
- RNA modifications and cancer
- Per- and polyfluoroalkyl substances research
- Birth, Development, and Health
Ningxia Medical University
2025
The Fourth People's Hospital of Ningxia Hui Autonomous Region
2025
Central South University
2015-2024
Kyoto University
2011-2015
Takayama Red Cross Hospital
2015
Zhengzhou University
2008
Previous investigations on chronic kidney disease of unknown etiology characterized by tubulointerstitial damages (CKDu) in the North Central Region (NCR) Sri Lanka have supported involvement social, environmental and genetic factors its pathogenesis.We conducted a social-environmental-and-genetic epidemiology study male population NCR to investigate contributors. We recruited 311 case-series patients 504 control candidates. Of candidates, 218 (43%) were eliminated because presence...
A gas chromatographic-mass spectrometric method has been developed and validated for the analysis of <i>cis</i>- <i>trans</i>-resveratrol simultaneously in matrices such as wine grape juice. Solid phase extraction resveratrol isomers on a C-18 column was followed by derivatization with bis-[trimethylsilyl]-trifluoroacetamide under optimized conditions gas-liquid chromatography an aliquot (1 µL) DB-5HT column. Selective ion monitoring performed at mass 444 quantification using ions 445 446...
Background and Purpose— Rupture of intracranial aneurysms (IAs) causes subarachnoid hemorrhage, leading to immediate death or severe disability. Identification the genetic factors involved is critical for disease prevention treatment. We aimed identify susceptibility genes IAs. Methods— Exome sequencing was performed in 12 families with histories multiple cases IA (number per family ≥3), a total 42 cases. Various filtering strategies were used select candidate variants. Replicate association...
Objective: Flow diverter stents (FDSs) have attracted interest for intracranial aneurysm (IA) treatment; however, occlusion of side branches and related complications been reported. This study aimed to investigate the effects FDSs in IA management when different arteries are covered. Materials methods A cross-sectional was conducted using PUBMED, Embase, Web Science, Cochrane databases include randomized or non-randomized comparative designed studies from January 2000 August 2022 which...
Solute carrier family 2 member 4- (SLC2A4-) retinol binding protein-4- (RBP4-) phosphoenolpyruvate carboxykinase 1 (PCK1)/phosphoinositide 3-kinase (PI3K) is an adipocyte derived "signalling pathway" that may contribute to the pathogenesis of type diabetes mellitus (T2DM). We explored whether single nucleotide polymorphisms (SNPs) these genes are associated with gestational (GDM).Case-control studies were conducted compare GDM and control groups. A total 334 cases 367 controls recruited....
Objective . This study mainly aimed to explore the association between brain-derived neurotropic factor (BDNF) Val66Met polymorphism and posttraumatic stress disorder (PTSD) among flood survivors in China. Methods Individuals who experienced 1998 Dongting Lake Southeast Huarong, China, were enrolled this study. Qualified health personnel carried out face-to-face interviews with participants. PTSD was identified using Checklist-Civilian version (PCL-C). Blood samples collected from...
RNF213 p.R4810K was identified as a susceptibility variant for moyamoya disease in Asia and non-moyamoya intracranial artery stenosis/occlusion Japan Korea recently. The occurrence of this evaluated patients with China.Two study populations were used study. One recruited from the Second Hospital Hebei Medical University April 2015 to May 2016. other archived DNA samples XiangYa collected 2014. investigated total 715 disease. carrier rate 507 normal individuals control.Six (0.84%) 2 controls...
RNF213 rare variant-p.R4810K (rs112735431) was significantly associated with intracranial artery stenosis/occlusion disease (ICASO) in Japan and Korea to a lesser degree China. Considering the allelic heterogeneity, we performed target exome sequencing of aim identify variants spectrum their association ICASO Chinese population further explore whether carrier patients present specific clinical phenotype.Target 250 using FastTarget technology. Various filtering process were used select...
Purpose: Genome-wide association studies (GWAS) have revealed that common variants on or near EDNRA, HDAC9, SOX17, RP1, CDKN2B-AS1, and RBBP8 genes are associated with intracranial aneurysm (IA) in European Japanese populations.However, due to population heterogeneity, whether these loci IA pathogenesis Chinese individuals is still unknown.The purpose of this study was investigate associations among GWAS-identified risk a population.Materials Methods: A total 765 (including 230 patients 535...
This study aimed to assess whether pregnancy and puerperium were associated with the risk of brain arteriovenous malformation (bAVM) haemorrhage.A retrospective review was conducted in Xiangya Hospital, Central South University from January 2012 December 2021. A case-crossover design adopted calculate incidence density bAVM-related haemorrhage among female patients (pregnancy puerperium) control (non-pregnancy non-puerperium) periods, according four scenarios observed different populations...
Background: Subarachnoid hemorrhage (SAH), primarily caused by rupture of intracranial aneurysm, has a high incidence rate in women. We aimed to evaluate the association between female hormonal and reproductive factors SAH. Methods: A prospective cohort 226,469 participants from UK Biobank was followed for median period 14.75 years. Cox proportional hazards models restricted cubic splines were used explore associations 13 major SAH, including menarche age, menopausal status, age at...
Abstract Objective The Tubridge flow diverter (TFD) was recently developed to treat intracranial aneurysm (IA). In this study, we aimed assess the safety and efficacy of novel device. Methods A retrospective cohort consecutive patients with IA recruited between June 2017 February 2022. studied outcomes were perioperative complications, clinical quality life, angiographic occlusion. Multivariate logistic regression performed explore potential predictors stroke events comprehensive literature...