A5113507830- Intracerebral and Subarachnoid Hemorrhage Research
- Stroke Rehabilitation and Recovery
- Acute Ischemic Stroke Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracranial Aneurysms: Treatment and Complications
- Functional Brain Connectivity Studies
- Radiomics and Machine Learning in Medical Imaging
- Cerebrovascular and Carotid Artery Diseases
- X-ray Diffraction in Crystallography
- Acupuncture Treatment Research Studies
- Heme Oxygenase-1 and Carbon Monoxide
- Parkinson's Disease Mechanisms and Treatments
- Crystallization and Solubility Studies
- Nanoplatforms for cancer theranostics
- Colorectal Cancer Surgical Treatments
- Neurological disorders and treatments
- Colorectal Cancer Screening and Detection
- Botulinum Toxin and Related Neurological Disorders
- Tissue Engineering and Regenerative Medicine
- Internet of Things and AI
- Currency Recognition and Detection
- Immunotherapy and Immune Responses
- Lung Cancer Research Studies
- Organizational and Employee Performance
- Vascular Malformations and Hemangiomas
Matsuyama Red Cross Hospital
2025
Central South University
2012-2024
Hunan Cancer Hospital
2019-2024
Hangzhou Medical College
2017-2023
Zhejiang Provincial People's Hospital
2017-2023
Peking University
2023
Peking University Cancer Hospital
2023
Massachusetts General Hospital
2020
Harvard University
2020
Changchun University of Chinese Medicine
2020
Schizophrenia is a severe mental illness associated with the symptoms such as hallucination and delusion. The objective of this study was to investigate abnormal resting-state functional connectivity patterns schizophrenic patients which could identify furthest from healthy controls. whole-brain fMRI performed on diagnosed schizophrenia (n = 22) age- gender-matched, control subjects 22). To differentiate individuals controls, multivariate classification analysis employed. weighted brain...
The degree of post-traumatic brain edema and dysfunction the blood-brain barrier (BBB) influences neurofunctional outcome after a traumatic injury (TBI). Previous studies have demonstrated that administration apolipoprotein E-mimetic peptide COG1410 reduces water content subarachnoid hemorrhage, intra-cerebral focal ischemia. However, effects on vasogenic following TBI are not known. current study evaluated 1 mg/kg daily versus saline administered intravenously controlled cortical impact...
Cholangiocarcinoma (CC) has a poor prognosis and few treatment options. Conversion surgery for unresectable CC been frequently reported; however, there are almost no reports of conversion after durvalumab plus gemcitabine cisplatin therapy. In this study, we report the case patient with hilar who received therapy achieved pathological complete response surgery. A 70-year-old man was diagnosed (cT3N1M0, Stage III C) based on biopsy common bile duct stenosis computed tomography (CT) magnetic...
Objective: Flow diverter stents (FDSs) have attracted interest for intracranial aneurysm (IA) treatment; however, occlusion of side branches and related complications been reported. This study aimed to investigate the effects FDSs in IA management when different arteries are covered. Materials methods A cross-sectional was conducted using PUBMED, Embase, Web Science, Cochrane databases include randomized or non-randomized comparative designed studies from January 2000 August 2022 which...
Early brain injury is proposed to be the primary cause of poor outcome after subarachnoid hemorrhage (SAH), which closely related neural apoptosis. To date, relationship between peroxisome proliferator-activated receptor β/δ (PPARβ/δ) and nuclear factor-κB/matrix metalloproteinase-9 (NF-κB/MMP-9) pathway, both are apoptotic effects, has been poorly studied in SAH. The present study was undertaken evaluate effects PPARβ/δ on early NF-κB/MMP-9 pathway SAH rats.SAH model established by...
Aims and objectives This study aims to investigate the application value of Internet‐based instant messaging software in follow‐up patients using peritoneal dialysis. Background Peritoneal dialysis is an effective renal replacement treatment for end‐stage disease. The clinical usefulness patients, including incidence peritonitis exit‐site infection, levels albumin electrolytes degree patients’ satisfaction, remains unknown. Design Between January 2009–April 2016, a total 160 underwent...
To investigate the performance of mean parametric values and texture features based on intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) identifying pathological complete response (pCR) to neoadjuvant chemoradiotherapy (nCRT) in locally advanced rectal cancer (LARC). Pretreatment IVIM-DWI was performed 41 LARC patients receiving nCRT this prospective study. The parameters (apparent diffusion coefficient, ADC; pure D; pseudo-diffusion D* perfusion fraction, f), first-order,...
COVID-19 caused by SARS-CoV-2 is a great threat to public health. We present the safety and immunogenicity data from phase I trial in China of an mRNA vaccine (LVRNA009). In single-centre, double-blind, placebo-controlled dose-escalation study, 72 healthy unvaccinated adults aged 18–59 years were randomized (3:1) receive LVRNA009 with one three dosage (25, 50 100 μg) or placebo, evaluate for safety, tolerability LVRNA009. All these participants received two injections 28 days apart. No...
Abstract Objective The Tubridge flow diverter (TFD) was recently developed to treat intracranial aneurysm (IA). In this study, we aimed assess the safety and efficacy of novel device. Methods A retrospective cohort consecutive patients with IA recruited between June 2017 February 2022. studied outcomes were perioperative complications, clinical quality life, angiographic occlusion. Multivariate logistic regression performed explore potential predictors stroke events comprehensive literature...
Background: Subarachnoid hemorrhage (SAH), primarily caused by rupture of intracranial aneurysm, has a high incidence rate in women. We aimed to evaluate the association between female hormonal and reproductive factors SAH. Methods: A prospective cohort 226,469 participants from UK Biobank was followed for median period 14.75 years. Cox proportional hazards models restricted cubic splines were used explore associations 13 major SAH, including menarche age, menopausal status, age at...
Objective: To investigate relationships between whole-brain functional changes and the performance of multiple cognitive functions in early Parkinson's disease (PD). Methods: In current study, we evaluated resting-state MRI (rsfMRI) data neuropsychological assessments for various a cohort with 84 PD patients from Progression Markers Initiative (PPMI). Eigenvector centrality (EC) mapping based on rsfMRI was used to identify connectivity brain areas correlated different scores at level....
Abstract Background: Tong Jing Tiao Xing tuina (TJTX) is a Chinese massage method. Excising with scalp acupuncture (ESA) treatment combining electroacupuncture physical therapy (PT), and yinao fujian formula (YNFJ) oral herbal granule medicine. The combination of the 3 methods called “Zhishen Tiaoxing” (ZSTX) rehabilitation program, which used as an alternative limb spasm after stroke. There little available evidence demonstrating its safety efficacy. Methods: This will be subject-blind,...
Novel coronavirus has infected 4.33 million people in more than 200 countries the current global outbreak of COVID-19. However, there is still no effective drug to treat disease, and acupuncture moxibustion utilized as adjuvant therapy for treatment COVID-19 China.Nine electronic databases: PubMed, EMBASE, Cochrane library, Web Science (WOS), Google Scholar, China National Knowledge Infrastructure (CNKI), Chinese Biomedical Literature Database (CBM), Scientific Journal (VIP), Wan Fang...
Nanomedicine has developed rapidly for improving the solubility of anti-cancer drugs, prolonging circulation time in body, and enhancing accumulation lesion through enhanced permeability retention (EPR) effect. First, a new type dithiolane trimethylene carbonate (MGN) was synthesized, an amphiphilic polymer PEG-P (ERF-MGN) synthesized based on MGN (ERF). Then, N-hydroxysuccinimide (NHS)-PEG-P prepared by further polymerizing NHS, which amidated with polypeptide to obtain CC11-PEG-P...