Nan Li

ORCID: 0000-0002-2932-9649
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Research Areas
  • Gestational Diabetes Research and Management
  • Birth, Development, and Health
  • Pregnancy and preeclampsia studies
  • Adipose Tissue and Metabolism
  • Folate and B Vitamins Research
  • Pain Mechanisms and Treatments
  • Alzheimer's disease research and treatments
  • Spine and Intervertebral Disc Pathology
  • Obesity, Physical Activity, Diet
  • Bariatric Surgery and Outcomes
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Land Use and Ecosystem Services
  • Iron Metabolism and Disorders
  • Vitamin D Research Studies
  • Cervical and Thoracic Myelopathy
  • Child Nutrition and Water Access
  • Spinal Fractures and Fixation Techniques
  • Preterm Birth and Chorioamnionitis
  • Liver Disease Diagnosis and Treatment
  • Mitochondrial Function and Pathology
  • Thermoregulation and physiological responses
  • Neuroscience and Neuropharmacology Research
  • Cardiovascular Health and Risk Factors
  • Climate Change and Health Impacts
  • Heavy Metal Exposure and Toxicity

Tsinghua University
2023-2025

Yangzhou University
2023-2025

Zhengzhou University
2025

Qufu Normal University
2023-2024

Peking University
2015-2024

Chinese PLA General Hospital
2011-2024

Wenzhou University
2014-2024

China Medical University
2024

First Hospital of China Medical University
2024

Jinan University
2013-2024

Background Preterm birth is the second leading cause of death in children under age five years worldwide, but etiology many cases remains enigmatic. The dogma that fetus resides a sterile environment being challenged by recent findings and question has arisen whether microbes colonize may be related to preterm birth. It been posited meconium reflects in-utero microbial environment. In this study, correlations between fetal intestinal bacteria from gestational were examined order suggest...

10.1371/journal.pone.0090784 article EN cc-by PLoS ONE 2014-03-10

To evaluate the value of fasting plasma glucose (FPG) in first prenatal visit to diagnose gestational diabetes mellitus (GDM).Medical records 17,186 pregnant women attending clinics 13 hospitals China, including Peking University First Hospital (PUFH), were examined. Patients with pre-GDM excluded; data for FPG at and one-step GDM screening 75-g oral tolerance test (OGTT) performed between 24 28 weeks gestation collected analyzed.The median ± SD was 4.58 0.437. decreased increasing age....

10.2337/dc12-1157 article EN cc-by-nc-nd Diabetes Care 2012-11-29

This study aimed to investigate the effects of exercise on excessive mitochondrial fission, insulin resistance, and inflammation in muscles diabetic rats. The role irisin/AMPK pathway regulating was also determined. Thirty-two 8-week-old male Wistar rats were randomly divided into four groups (n = 8 per group): one control group (Con) three experimental groups. Type 2 diabetes mellitus (T2DM) induced via a high-fat diet followed by single intraperitoneal injection streptozotocin (STZ) at...

10.1038/s41598-024-61415-6 article EN cc-by Scientific Reports 2024-05-09

The objective of this study is to determine the incidence rate and risk factors tuberculosis (TB) among HIV-infected adults accessing antiretroviral therapy (ART) in Tanzania.A prospective observational attending HIV clinics Dar es Salaam.We estimated TB rates patients prior after ART initiation. We used Cox proportional hazard regressions predictors incident enrolled care treatment programme.We assessed 67 686 for a median follow-up period 24 (interquartile range: 8-49) months; 7602 were...

10.1097/qad.0000000000000705 article EN AIDS 2015-06-19

Background Despite the sharp decline in global under-5 deaths since 1990, uneven progress has been achieved across and within countries. In sub-Saharan Africa (SSA), Millennium Development Goals (MDGs) for child mortality were met only by a few Valid concerns exist as to whether region would meet new Sustainable (SDGs) mortality. We therefore examine further sources of variation assessing age patterns, trends, forecasts rates. Methods findings Data came from 106 nationally representative...

10.1371/journal.pmed.1002757 article EN cc-by PLoS Medicine 2019-03-12

Background: The frequency of take-out food consumption has increased rapidly among Chinese college students, which contributed to high obesity prevalence. However, the relationships between consumption, body mass index (BMI), and other individual factors influencing eating behavior students are still unclear. This study explored association with gender, BMI, physical activity, preference for high-fat high-sugar (HFHS) food, major category, degree level students. Methods: Cross-sectional data...

10.3390/ijerph16061071 article EN International Journal of Environmental Research and Public Health 2019-03-25

A novel electrochemical immunosensor fabricated from gold compact disc electrodes was designed for rapid evaluation of aggregation processes that lead to the formation oligomeric and fibrillar states amyloid-beta1–42 (Aβ1–42) during Alzheimer's disease. Conformation-specific antibodies were immobilized on surface electrode using a 3,3′-dithiobis (sulfosuccinimidyl) propionate (DTSSP) linker. Surface binding events analyzed by impedance spectroscopy (EIS) in which an antigen–antibody complex...

10.1021/ac500424t article EN Analytical Chemistry 2014-04-06

Young adults accounted for 10-14% of ischemic stroke patients. The risk factors may differ in this population from elder In addition, the associated with recurrence have not been well investigated.The study aimed to investigate characteristics and young adults.Clinical data 1,395 patients age 18-45 years who were treated between 2008 2014 3 centers located northern China was reviewed. first onset taken as initial events recurrent end point events. events, age, gender, duration after stroke,...

10.1159/000455093 article EN cc-by-nc-nd European Neurology 2017-01-01

Studies have shown that maternal blood pressure level is associated with neonatal birthweight, but the results are not exactly consistent. As most common hypertensive disorders during pregnancy, mechanism of gestational hypertension and pre-eclampsia affect fetal growth remain unclear. Our objective was to examine association risk low birthweight (LBW) small-for-gestational-age (SGA). Data were obtained from China-US Collaborative Project for Neural Tube Defects Prevention, a large...

10.1111/jch.14176 article EN cc-by-nc-nd Journal of Clinical Hypertension 2021-01-28

Abstract Minimally invasive biodegradable implants with regeneration have been a frontier trend in clinic. Degeneration of nucleus pulposus (NP) is irreversible most spine diseases, and traditional spinal fusion or discectomy usually injure adjacent segments. Here, an innovative minimally NP scaffold function inspired by cucumber tendril developed using shape memory polymer poly(glycerol-dodecanoate) (PGD), whose mechanical property controlled to the similar human adjusting synthetic...

10.1038/s41467-023-39604-0 article EN cc-by Nature Communications 2023-06-30

Abstract Aims To investigate the sex‐specific associations between predicted skeletal muscle mass index (pSMI) and incident type 2 diabetes in a retrospective longitudinal cohort of Chinese men women. Materials Methods We enrolled adults without at baseline from WATCH (West chinA adulT health CoHort), large check‐up‐based database. calculated pSMI to estimate muscular mass, measured blood glucose variables assessed self‐reported history identify new‐onset diabetes. The nonlinear association...

10.1111/dom.15373 article EN Diabetes Obesity and Metabolism 2023-11-23

Phthalates (PAEs) and polycyclic aromatic hydrocarbons (PAHs) are frequently detected in females of reproductive age. Many studies have found that environmental PAE PAH levels independent risk factors for gestational hypertension. However, exposure to both components is a more realistic scenario. To better assess the health effects PAEs PAHs pregnant women, we explored associations individual combined with This nested case-control study was component prospective cohort conducted Beijing,...

10.1016/j.envint.2024.108562 article EN cc-by-nc Environment International 2024-03-01

Plants have evolved various mechanisms that protect against the harmful effects of UV-B radiation (280–315 nm) on growth and development. Cyclobutane pyrimidine dimer (CPD) photolyase, repair enzyme for UV-B-induced CPDs, is essential protecting cells from radiation. Expression CPD photolyase gene ( PHR ) controlled by light with wavelengths including UV-B, but this regulation remain poorly understood. In study, we investigated expression wavelengths, in particular low-fluence (280 nm, 0.2...

10.1093/pcp/pcv121 article EN Plant and Cell Physiology 2015-08-12

Quercetin, the most widely distributed flavonoid, has been shown to have multiple properties and beneficial effects on various metabolic diseases. Thus, our aim was investigate underlying mechanism whereby quercetin regulates renal lipid accumulation ameliorates early diabetic injuries in Lepr

10.2147/dmso.s195456 article EN cc-by-nc Diabetes Metabolic Syndrome and Obesity 2019-05-01

To investigate the impact of gestational hypertension and pre-eclampsia on preterm birth.

10.1136/bmjopen-2021-058068 article EN cc-by-nc BMJ Open 2022-09-01

A novel pretreatment method ionic liquid-based dispersive liquid-liquid microextraction followed by high-performance liquid chromatography (HPLC) was established and applied in the analysis of silychristin, silydianin, silybin, silybin B, isosilybin A, B Silybum marianum. The critical parameters affecting micro-extraction (DLLME), including selection solvent extraction solvent, volume adjustment pH, salt concentration, time, were investigated single factor study. Under optimum conditions,...

10.21577/0100-4042.20250109 article EN cc-by-nc Química Nova 2025-01-01

Abstract Life cycle assessment (LCA) hinges on the transparency and reliability of inventory data. However, background life (LCI) data sources remains unexamined. This research assesses in mainstream LCI databases using a two‐step examination system based source findability accessibility. Six major (ecoinvent, GaBi, U.S. Cycle Inventory Database, European Database for Environmental Analysis, Chinese Database) were analyzed by sampling processes tracing their sources. The results reveal...

10.1111/jiec.70010 article EN Journal of Industrial Ecology 2025-03-07
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