A5037278366- Infant Nutrition and Health
- Salmonella and Campylobacter epidemiology
- Gut microbiota and health
- Vector-borne infectious diseases
- Infant Health and Development
- Probiotics and Fermented Foods
- Food Safety and Hygiene
- Listeria monocytogenes in Food Safety
- HIV/AIDS Research and Interventions
- Streptococcal Infections and Treatments
- Escherichia coli research studies
- HIV/AIDS drug development and treatment
- SARS-CoV-2 and COVID-19 Research
- Viral Infections and Vectors
- Enterobacteriaceae and Cronobacter Research
- Clinical Nutrition and Gastroenterology
- Reproductive tract infections research
- COVID-19 Clinical Research Studies
- Pneumonia and Respiratory Infections
- Rabies epidemiology and control
- Aortic Thrombus and Embolism
- COVID-19 Impact on Reproduction
- Urinary Tract Infections Management
- Microbial metabolism and enzyme function
- Zoonotic diseases and public health
Hvidovre Hospital
2021-2025
Copenhagen University Hospital
2021-2025
University of Copenhagen
2009-2024
Statens Serum Institut
2007-2021
Amager Hospital
2021
Rigshospitalet
2008
We describe an outbreak of Shiga toxin-producing Escherichia coli O26:H11 infection in 20 patients (median age, 2 years). The source the was organic fermented beef sausage. discovered by using credit card information to obtain and compare customer transaction records from computer systems supermarkets.
Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency in newborn neonates. Bacteria are believed to be important pathogenesis of NEC but bacterial characterization has only been done on human faecal samples and experimental animal studies. The aim this study was investigate microbial composition relative number bacteria inflamed intestinal tissue surgically removed from neonates diagnosed with (n=24). populations specimens were characterized by laser capture...
Culture independent methods are used widely in diagnostic laboratories for infectious disease Isolation of genomic DNA from clinical samples is the first and important step procedure. Several procedures extracting faecal have been described, including different mechanical cell disruptors. To our knowledge, use TissueLyser as a disruptor on before extraction has not previously described. The purpose study was to implement method preparing optimal extraction. Thus, three human faeces were...
Feces from 1,451 horses entering a veterinary hospital over 13-month period were cultured for salmonella. A total of 46 (3.2%) yielded 1 or more salmonella-positive fecal cultures. Twenty found to be excreting salmonella in the feces on admission, and 5 these later had severe diarrhea associated with enteric salmonellosis. Abdominal surgery other stresses all cases Serotypes isolated included Salmonella agona (15), S anatum (14), typhimurium (7), var copenhagen (4), infantis (2), montevideo...
Premature birth, especially if born before week 32 of gestation, is associated with increased risk neonatal morbidity and mortality. Prophylactic use probiotics has been suggested to protect preterm infants via supporting a healthy gut microbiota (GM) development, but the strains doses vary between studies. In this study, we profiled GM 5, 10 30-day fecal samples from two cohorts neonates (born <30 weeks gestation) recruited in same intensive care unit. One cohort (n = 165) was September...
Maternal-foetal infection by Listeria monocytogenes is a rare complication in pregnancy. In the period 1994–2005, 37 culture-confirmed cases of maternal-foetal infections were reported Denmark. We examined 36 patients' files order to evaluate risk factors, clinical and laboratory findings, response therapy, outcome for listeriosis. Patient data bacteriological findings divided into 2 groups comparison: 1 group with children born alive (n=24) another abortion or stillbirth (n=12). 23 survived...
In 2009, 97 cases of listeriosis were reported in Denmark (1.8 per 100,000), a significant rise over the previous year. The increase was seen both bacteraemia and meningitis affected mainly people aged 70 years older. A foodborne outbreak eight identified by pulsed-field gel electrophoresis typing. No explanation has so far been found for marked incidence. An increasing trend observed since 2003 possible explanations are discussed.
ABSTRACT Aim There is limited evidence on the use of oral doxycycline in young children. We evaluated feasibility and effectiveness children under 9 years with neuroborreliosis. Methods This retrospective study included all age treated for neuroborreliosis Capital Region Denmark from 2019 to 2023. Patients were identified through Borrelia burgdorferi antibody tests International Classification Disease, 10th revision codes. Outcomes change treatment route, intolerable adverse effects...
Abstract Background Dolutegravir (DTG) is a preferred anchor antiretroviral therapy (ART) for children and adolescents living with HIV (CALHIV). Methods We assessed the effectiveness safety of DTG in CALHIV aged 0-18 years at start routine care Europe Thailand, including viral suppression (viral load (VL)&lt;50copies/mL), cumulative incidence failure (VF) (confirmed VL≥400copies/mL) associated factors, adverse events (AEs) discontinuation. VF on was compared to protease inhibitor...
Query (Q) fever was virtually unknown in Denmark 2005, when, after the introduction of new sensitive diagnostic methods for Coxiella burnetii, an increasing number positive cattle created concern among people with frequent exposure. This led to a dramatic rise examinations Q humans following 2 years. The aim our study assess indication testing and symptoms individuals serological signs infection C. burnetii. We performed case-review seropositives all tested 2006-07 Denmark. Seropositive...
Abstract Aim We aimed to investigate the causes of acute peripheral facial palsy (PFP) in Danish children and explore whether neuroborreliosis‐related PFP could be diagnosed without lumbar puncture using clinical symptoms serum Borrelia burgdorferi (Bb) antibodies. Methods This retrospective population‐based cohort study included undergoing for between 2019 2023 Denmark's Capital Region. Diagnostic performance measures were compared Bb IgG alone risk scores combining with parameters. Results...
An outbreak of Verocytotoxin-producing Escherichia coli (VTEC) O26:H11 occurred in Denmark from February to April 2007. The was detected at Statens Serum Institut (Danish National Institute Health, SSI) on 9 March by routine PFGE typing VTEC isolates collected as part the laboratory surveillance system.
In Denmark, severe acute respiratory syndrome coronavirus 2 antibodies were assessed in a cross-sectional study among 1033 children visiting pediatric departments and 750 blood donors June 2020, using point-of-care test. Antibodies detected 17 (1.6%) 15 (2.0%) (P = 0.58). conclusion, adults infected to similar low degree.
Abstract BACKGROUND Fast identification of severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) infected individuals is a strategically vital task to ensure correct management and quarantine. Rapid antigen test could be supplement the standard-of-care Nucleic Acid Amplification Test (NAAT). The aim this study was determine accuracy BD Veritor SARS-CoV-2 as screening instrument in hospital setting. METHODS A cohort prospective samples were collected from staff patients at Emergency,...
To the Editors: Less than 1% of pediatric Salmonella infections present with osteomyelitis often associated to hemoglobinopathies, yet extraordinary in immunocompetent children.1,2 Despite relevant antibiotic therapy, treatment is prolonged and duration without international consensus. We report a case (SOM) an 10-month-old girl. A previously healthy girl was admitted ward due persistent fever being unable crawl. Physical examination revealed (38.1°C), erythema, swelling, pain, dysfunction...
Group B Streptococcus (GBS) infection in infants may result both respiratory, cardiovascular, and neurological dysfunction ultimately death of the infant. Surveillance GBS strains their clinical characteristics guide development effective vaccines other potential treatments have implications for future prognostics infant care. Therefore, we aimed to study serotypes clonal complexes (CC) Danish with early onset (EOD) (0-6 days life) late-onset (LOD) (7-89 estimate association between strain...
<h3>Background</h3> Increasingly, women living with HIV in resource-rich settings are choosing to breastfeed, but experience managing maternal viraemia during breastfeeding and transmission risks the infant limited. In low- middle-income settings, overall postnatal risk of via breast milk when treated combination ART has been reported as 0.30 (95% CI 0.1–0.6) 1.08% 0.32–1.85) at 6 months.<sup>1 2</sup> <h3>Method</h3> Case series from Paediatric Virtual Clinic (PVC) including national...