Francisco Ruiz

ORCID: 0000-0001-6067-3459
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About
Contact & Profiles
Research Areas
  • Ovarian function and disorders
  • Reproductive Biology and Fertility
  • Assisted Reproductive Technology and Twin Pregnancy
  • Reproductive Health and Technologies
  • Sperm and Testicular Function
  • Uterine Myomas and Treatments
  • Endometriosis Research and Treatment
  • Bioethics and Human Rights Issues
  • Reproductive System and Pregnancy
  • Ectopic Pregnancy Diagnosis and Management
  • Ethics and bioethics in healthcare
  • Intestinal and Peritoneal Adhesions
  • Genetics, Aging, and Longevity in Model Organisms
  • Pluripotent Stem Cells Research
  • Gynecological conditions and treatments
  • Mitochondrial Function and Pathology

IVI Middle East Fertility Clinic
2016-2025

IVI Madrid Clinic
2012-2014

Universidad Rey Juan Carlos
2010-2011

What is the diagnostic performance of ART-ET screening tool, an easy-to-use non-invasive tool for prediction difficult embryo transfers? A simple scoring transvaginal ultrasound examination cervical canal can predict transfers with high specificity, positive likelihood ratio, and accuracy; inclusion position history cesarean without a vaginal delivery improved predictive performance. Difficult transfer procedures are associated significantly lower clinical pregnancy live birth rates, some...

10.1093/humrep/deaf002 article EN Human Reproduction 2025-01-07

Final oocyte maturation using GnRH-agonist trigger in a GnRH-antagonist protocol is increasingly common, as ovarian hyperstimulation syndrome almost completely avoided. However, this approach might lead to reduced pregnancy rates due severe luteolysis. This proof of concept study evaluated the extend luteolysis by measuring progesterone levels 48 hours after retrieval 51 patients, who received for final risk syndrome. It was shown, that GnRHa-trigger differs greatly among with ranging from...

10.1371/journal.pone.0176600 article EN cc-by PLoS ONE 2017-05-01

Over the past few years, use of Gonadotropin-releasing-hormone (GnRH)-agonist for final oocyte maturation in GnRH-antagonist-protocols stimulated IVF/ICSI cycles has gained worldwide acceptance, as this approach reduces significantly risk development ovarian hyperstimulation syndrome (OHSS). Final with GnRH-agonist leads to sever luteolysis, which cannot be counterbalanced using standard luteal phase support purely progesterone (P4) application and therefore administration hCG or high doses...

10.1080/09513590.2016.1266325 article EN Gynecological Endocrinology 2016-12-26

In the past years, individualization of assisted reproductive technique (ART)-treatment is increasingly common to customize treatment protocol patient's specific conditions. The use GnRH-agonist for final oocyte maturation in a gonadotropin-releasing hormone (GnRH)-antagonist best approach reduce risk ovarian hyperstimulation high responder patients. However, due severe luteolysis, outcome with this combination vaginal progesterone as luteal phase support, was poor. Cycle segmentation...

10.1080/09513590.2017.1391204 article EN Gynecological Endocrinology 2017-10-16

OBJECTIVE: Recently, controversy has arisen regarding the use of oral contraceptive pill and impact on implantation rates in patients undergoing IVF/ICSI. This debate is still open as cycle scheduling a common practice most units. Thus, we decided to compare outome after with standard long protocol versus OCPs GnRH antagonist cycles.DESIGN: Prospective, randomized, controlled trial.MATERIALS AND METHODS: Regular cycling women under 39 years, <3 previous IVF attempts were enrolled this trial....

10.1016/j.fertnstert.2010.07.107 article EN publisher-specific-oa Fertility and Sterility 2010-08-27

Objective: To evaluate intraday serum progesterone levels on the day of final oocyte maturation in women undergoing ovarian stimulation a GnRH-antagonist protocol. Study design, size, and duration: The study was done as prospective observational at Private IVF centre Muscat, Oman. 30 patients were recruited from May 2018 to March 2019. Patients: Thirty with primary/secondary infertility an indication for IVF/ICSI treatment. registered clinicaltrials.gov under number: NCT03519776. Main...

10.3389/fendo.2019.00806 article EN cc-by Frontiers in Endocrinology 2019-11-20

Background/Aim: To investigate which FSH, recombinant or urinary, works better in low responders patients after initial stimulation with clomiphene citrate (CC) and antagonist protocol. Matherial Methods: Retrospective study historical controls an University-affiliated infertility center. A total of 140 a previous response IVF / ICSI cycle were included. 70 undergoing GnRH received controlled ovarian oral human menopausal gonadotropins (Group A). Similarly, stimulated CC follicle-stimulating...

10.4103/2348-2907.127093 article EN IVF Lite 2014-01-01

Objective . To report the arrest of euploid embryos with high mtDNA content. Design A 2 cases. Setting Private fertility clinic. Patients patients, 45 and 40 years old undergoing IVF treatment. Interventions Mature oocytes were collected vitrified from two ovarian stimulations. Postthaw, survived mature underwent fertilization by intracytoplasmic sperm injection (ICSI). Preimplantation genetic screening (PGS) mitochondrial DNA (mtDNA) copy number done using next generation sequencing (NGS)....

10.1155/2017/4397434 article EN cc-by Case Reports in Genetics 2017-01-01

Introduction Endometrioma is present in 17% to 40% of women with endometriosis. Since it has been traditionally believed that the presence an endometrioma adversely affects outcome assisted reproductive technology (ART), surgery suggested by many practitioners before advancing ART, hope improving results. Scientific Evidence In article, we outline impact on ovarian reserve and describe how surgical resection endometriotic cyst reserve, response after stimulation ART outcome. Several studies...

10.5301/je.5000242 article EN Journal of Endometriosis and Pelvic Pain Disorders 2016-04-01

Treating infertility in women with advanced maternal age has become a common practice reproductive medicine, especially developed countries, owing to postponing maternity. There are some characteristics that define these patients make them particularly difficult manage. One of the most issues is poor response after ovarian stimulation observed majority above 40 years. This presents complicated situations almost impossible reverse, such as low total number oocytes retrieved puncture, and...

10.1586/eog.11.62 article EN Expert Review of Obstetrics & Gynecology 2011-11-01
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