A5013481275- Reproductive Biology and Fertility
- Prenatal Screening and Diagnostics
- Assisted Reproductive Technology and Twin Pregnancy
- Pluripotent Stem Cells Research
- Ovarian function and disorders
- Renal and related cancers
- Reproductive Health and Technologies
- Mitochondrial Function and Pathology
- Reproductive System and Pregnancy
- Genetics, Aging, and Longevity in Model Organisms
- Genetic Syndromes and Imprinting
- Sperm and Testicular Function
- CRISPR and Genetic Engineering
IVI Middle East Fertility Clinic
2017-2023
Koç University
2023
Middle East Technical University
2023
University Children's Hospital Tübingen
2023
IVI Madrid Clinic
2012-2016
How reliable are cleavage stage and trophectoderm (TE) biopsies compared to inner cell mass (ICM) biopsies?The reliability of TE biopsy ICM is almost perfect, but only substantial between biopsy.One the prevailing reasons for implantation failure presumed be chromosomal aneuploidy in human preimplantation embryos. Preimplantation genetic testing aneuploidies (PGT-A) has been introduced into assisted reproduction an effort increase pregnancy rates. Increasing evidence indicates that results...
The aneuploidy rate is higher in poor-quality sperm samples, which also have DNA fragmentation index values. aim of this study was to assess the relationship between samples from infertile men belonging couples with recurrent miscarriage or implantation failure and spermatozoa as well embryos patients.This prospective evaluated damage fresh processed (density gradient centrifugation) ejaculated biopsied fertility cycles. Fluorescence situ hybridization used for analysis. Results were...
One of the most important limitations genetic testing in preimplantation embryos is embryonic mosaicism, especially when performed on D3 with only a single blastomere evaluated. Previous publications, using Array-Comparative Genomic Hybridization (a-CGH) to compare day 3 (D3) biopsies versus trophectoderm for analysis aneuploid embryos, showed similar high concordance rates per embryo diagnosis and biopsies. Next generation sequencing (NGS) was introduced lately as new technique aneuploidies...
ABSTRACT Although numerous studies have examined whether endometrial thickness (ET) independently affects the live birth rate (LBR) after an embryo transfer, contradictory conclusions resulted in unclear answer. It has been hypothesized that a thin endometrium decreases implantation rates possibly due to elevated oxygen concentration from spiral arteries; however, this mechanism not unequivocally demonstrated. This retrospective analysis aimed investigate ET LBR frozen transfer cycle. All...
Objective . To report the arrest of euploid embryos with high mtDNA content. Design A 2 cases. Setting Private fertility clinic. Patients patients, 45 and 40 years old undergoing IVF treatment. Interventions Mature oocytes were collected vitrified from two ovarian stimulations. Postthaw, survived mature underwent fertilization by intracytoplasmic sperm injection (ICSI). Preimplantation genetic screening (PGS) mitochondrial DNA (mtDNA) copy number done using next generation sequencing (NGS)....