- Reproductive Biology and Fertility
- Prenatal Screening and Diagnostics
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive Health and Technologies
- Ovarian function and disorders
- Sperm and Testicular Function
- Pluripotent Stem Cells Research
- Renal and related cancers
- Genetic Syndromes and Imprinting
- Genomic variations and chromosomal abnormalities
- Chromosomal and Genetic Variations
- Hormonal and reproductive studies
- Kidney Stones and Urolithiasis Treatments
- Tissue Engineering and Regenerative Medicine
- Genetics, Aging, and Longevity in Model Organisms
- Cancer Genomics and Diagnostics
- Cancer-related molecular mechanisms research
- Telomeres, Telomerase, and Senescence
- Molecular Biology Techniques and Applications
- Child Nutrition and Water Access
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Animal Virus Infections Studies
- Environmental DNA in Biodiversity Studies
- Ethics and Legal Issues in Pediatric Healthcare
- Pediatric Urology and Nephrology Studies
IVI Madrid Clinic
2013-2023
Guardia Civil
2020
Universidad Rey Juan Carlos
2014-2020
Valencian Infertility Institute
2007-2013
Center for Human Reproduction
2012
Papageorgiou General Hospital
2012
Servicio de Salud de Castilla La Mancha
2008
Are the morphokinetics of growing embryos affected by type culture media utilized? Morphokinetic parameters used for embryo selection are not between two different concept analyzed. Studies on effect human have focused evaluating in-house and commercially available as well comparing outcomes among commercial media. Nonetheless, evaluation development in these studies was based static observations very little is known from a dynamic point view. Prospective cohort study, October 2010 April...
Abstract The field of preimplantation genetic testing (PGT) is evolving fast, and best practice advice essential for regulation standardisation diagnostic testing. previous ESHRE guidelines on PGD, published in 2005 2011, are considered outdated, the development new papers outlining recommendations good PGT was necessary. current paper provides technical aspects embryo biopsy covers procedure, cryopreservation laboratory issues training, addition to strengths limitations specific currently...
ABSTRACT STUDY QUESTION What are the trends and developments in preimplantation genetic testing (PGT) 2018 as compared to previous years? SUMMARY ANSWER The main observed this 21st dataset on PGT that implementation of trophectoderm biopsy with comprehensive whole-genome is most often applied for PGT-A concurrent PGT-M/SR/A, while PGT-M PGT-SR, single-cell PCR FISH still prevail. WHAT IS KNOWN ALREADY Since it was established 1997, ESHRE Consortium has been collecting analysing data from...
Magnetic-activated cell sorting (MACS) can be used to separate apoptotic sperm with high proportions of fragmented DNA from the rest, thus improving overall quality seminal sample. Therefore, aim this retrospective study was investigate efficiency MACS technique increase reproductive outcomes in patients levels fragmentation (SDF) undergoing intracytoplasmic sperm-injection (ICSI) cycles. In study, we analyzed a total 724 assisted-reproduction-technique (ART) cycles that were divided into...
The aneuploidy rate is higher in poor-quality sperm samples, which also have DNA fragmentation index values. aim of this study was to assess the relationship between samples from infertile men belonging couples with recurrent miscarriage or implantation failure and spermatozoa as well embryos patients.This prospective evaluated damage fresh processed (density gradient centrifugation) ejaculated biopsied fertility cycles. Fluorescence situ hybridization used for analysis. Results were...
Abstract Background The goal of this study was to investigate which factors, excluding embryo aneuploidies, are associated with miscarriage in patients who have undergone a single euploid blastocyst transfer. Methods Retrospective, observational and multicenter 2832 undergoing preimplantational genetic testing for aneuploidies (PGT-A) due repeated implantation failure, recurrent pregnancy loss, advanced maternal age or severe male factor were transferred one embryo. Results One the main...
In brief COVID-19 does not affect the telomeres or fertility outcomes in mild cases. However, women with severe symptoms, of granulosa cells are shorter, and oocyte maturation rate is decreased. Abstract The coronavirus SARS-CoV-2 causes disease affects primarily lungs also other organs, causing accelerated cell aging. One main pathways involved aging telomere attrition, which ultimately leads to defective tissue regeneration organ dysfunction. Indeed, short aged people aggravate survivors...
Introduction: Weight loss amongst women with polycystic ovary syndrome (PCOS) is crucial to reduce the risk of endocrine, reproductive and metabolic complications including hirsutism, menstrual disturbances cardiovascular disease. With approximately 50% PCOS being overweight or obese, effective dietary management weight in essential. However, there inconsistent evidence as whether specifically modified diets (e.g. reduced carbohydrate diets) are more at achieving than conventional healthy...
In this report, we describe for the first time a pregnancy using sperm retrieved from an azoospermic man with kidney transplant due to type I primary hyperoxaluria. It is case that were able find in literature both male infertility and hystopathologic findings.
Abstract Study question Which are the trends shown in data collection XXII of European Society Human Reproduction and Embryology (ESHRE) PGT Consortium compared with previous years? Summary answer Data XXII, year 2020, represents valuable on activity (mainly) Europe reports main observed, being further expansion comprehensive testing technology PGT-SR PGT-A. What is known already The ESHRE was set up 1997 from that time has been collecting database comprises world’s largest / PGT-A providing...