A5019981364- Reproductive Biology and Fertility
- Ovarian function and disorders
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive Health and Technologies
- Renal and related cancers
- Prenatal Screening and Diagnostics
- Ectopic Pregnancy Diagnosis and Management
- Pregnancy and preeclampsia studies
- Ovarian cancer diagnosis and treatment
- Reproductive System and Pregnancy
- Sperm and Testicular Function
- Endometriosis Research and Treatment
- Gynecological conditions and treatments
- Speech and dialogue systems
- Cancer Genomics and Diagnostics
- Periodontal Regeneration and Treatments
- Genomic variations and chromosomal abnormalities
- Maternal and Neonatal Healthcare
- Pluripotent Stem Cells Research
- Urticaria and Related Conditions
- Preterm Birth and Chorioamnionitis
- Genetic Syndromes and Imprinting
- Phonetics and Phonology Research
Hygeia Hospital
2024
Mitera Hospital
2021-2022
University of Nottingham
2016-2020
Eugonia
2008-2020
Assisting Nature
2013
What recommendations can be provided on the approach to and use of time-lapse technology (TLT) in an IVF laboratory?The present ESHRE document provides 11 how introduce TLT laboratory.Studies have been published clinical embryology. However, a systematic assessment this is currently missing.A working group members Steering Committee Special Interest Group Embryology selected was formed order write practical aspects for laboratory.The included different nationalities with internationally...
Abstract STUDY QUESTION Which add-ons are safe and effective to be used in ART treatment? SUMMARY ANSWER Forty-two recommendations were formulated on the use of diagnosis fertility problems, IVF laboratory clinical management treatment. WHAT IS KNOWN ALREADY The innovative nature combined with extremely high motivation patients has opened door wide application what become known as ‘add-ons’ reproductive medicine. These supplementary options available addition standard procedures, typically...
Women with polycystic ovary syndrome (PCOS) are at risk of developing ovarian hyperstimulation (OHSS) during stimulation. Use GnRH antagonist in the general subfertile population is associated lower incidence OHSS than agonists and similar probability live birth but it unclear if this true for patients PCOS. Our aim was to compare flexible agonist long protocols PCOS undergoing IVF (primary end-point: ongoing pregnancy rate per patient randomized). In randomised controlled trial (RCT), 220...
STUDY QUESTIONWhat is the proper way of assessing effect progesterone elevation (PE) on day hCG live birth in women undergoing fresh embryo transfer after vitro fertilization (IVF) using GnRH analogues and gonadotrophins?
Abstract The field of preimplantation genetic testing (PGT) is evolving fast, and best practice advice essential for regulation standardisation diagnostic testing. previous ESHRE guidelines on PGD, published in 2005 2011, are considered outdated, the development new papers outlining recommendations good PGT was necessary. current paper provides technical aspects embryo biopsy covers procedure, cryopreservation laboratory issues training, addition to strengths limitations specific currently...
Abstract STUDY QUESTION How should ART/preimplantation genetic testing (PGT) centres manage the detection of chromosomal mosaicism following PGT? SUMMARY ANSWER Thirty good practice recommendations were formulated that can be used by ART/PGT as a basis for their own policy with regards to management ‘mosaic’ embryos. WHAT IS KNOWN ALREADY The use comprehensive chromosome screening technologies has provided variety data on incidence at preimplantation stage development and evidence is...
STUDY QUESTIONDo live birth rates differ between modified natural cycles (MNCs) and using high-dose follicle stimulating hormone (HDFSH) with gonadotrophin-releasing (GnRH) antagonist in poor responder patients?
Can the priorities for future research in infertility be identified?The top 10 four areas of male infertility, female and unexplained medically assisted reproduction ethics, access organization care people with fertility problems were identified.Many fundamental questions regarding prevention, management consequences remain unanswered. This is a barrier to improving received by those problems.Potential collated from an initial international survey, systematic review clinical practice...
Although initial studies in poor responders using GnRH antagonists have reported encouraging results, they are limited number, only a few of them prospective, while the majority is characterized by power to detect clinically important difference. A randomized controlled trial was performed patients with one or more previous failed IVF cycles which five less oocytes were retrieved, ≥300 IU gonadotrophins/day. Patients computer-generated list and treated either flare-up agonist protocol (n =...
Management of established severe OHSS requires prolonged hospitalization, occasionally in intensive care units, accompanied by multiple ascites punctures, correction intravascular fluid volume and electrolyte imbalance. The aim the present study was to evaluate whether it is feasible manage women with as outpatients treating them GnRH antagonists luteal phase.This a single-centre, prospective, observational, cohort study. Forty patients diagnosed OHSS, five days post oocyte retrieval, were...
Are there any baseline predictors of progesterone elevation (PE) on the day human chorionic gonadotrophin (hCG) which are not associated with intensity ovarian stimulation in women undergoing vitro fertilization (IVF) using follicle stimulating hormone (FSH) and gonadotrophin-releasing (GnRH) antagonists? Basal (Day 2 menstrual cycle) serum concentration history PE variables that can predict occurrence hCG independently stimulation. is magnitude response to For this reason, it has been...
STUDY QUESTIONDo high-risk patients who develop severe early ovarian hyperstimulation syndrome (OHSS) and receive low-dose GnRH antagonist in the luteal phase have lower live birth rates compared with do not OHSS phase?
To investigate the kinetics of serum vascular endothelial growth factor (VEGF) following gonadotrophin-releasing hormone (GnRH) antagonist administration in luteal phase women with established severe early ovarian hyperstimulation syndrome (OHSS).Pilot observational cohort study.Private vitro fertilisation (IVF) Unit.Twelve IVF diagnosed OHSS 5 days post oocyte retrieval (POR).Women undergoing POR were given 0.25 mg GnRH for 4 days, from day until and including 8 POR, combined elective...
<b>Context:</b> Metabolomics was introduced in human <i>in vitro</i> fertilization (IVF) for noninvasive identification of viable embryos with the highest developmental competence. <b>Aims:</b> To determine whether embryo selection using a commercial version metabolomic analysis leads to increased implantation rates (IRs) fetal cardiac activity (FCA) compared morphology evaluation alone. <b>Setting and Design:</b> Randomized controlled trial from April December 2010 at private IVF unit. The...
Abstract Fertilization underpins the vital transition from gametic meiosis to embryonic mitosis. For decades, in human IVF, microscopic observation at a single time point has limited our appreciation of morphokinetic complexity this process. More recently, introduction lapse technology—also enhanced by combination with artificial intelligence—has revealed finest details beginning development. Overall, picture finally emerged which precise timing, morphology and geometry several fertilization...