- Ovarian function and disorders
- Reproductive Biology and Fertility
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive Health and Technologies
- Ectopic Pregnancy Diagnosis and Management
- Reproductive System and Pregnancy
- Ovarian cancer diagnosis and treatment
- Pregnancy and preeclampsia studies
- Renal and related cancers
- Endometriosis Research and Treatment
- Phonetics and Phonology Research
- Reproductive Health and Contraception
- Delphi Technique in Research
- Prenatal Screening and Diagnostics
- Sexual Differentiation and Disorders
- Maternal and Neonatal Healthcare
- Sperm and Testicular Function
- Gynecological conditions and treatments
- Speech and dialogue systems
Eugonia
2014-2024
Assisting Nature
2013-2023
Aristotle University of Thessaloniki
2019-2020
National and Kapodistrian University of Athens
2005
Abstract STUDY QUESTION What is the recommended management of ovarian stimulation, based on best available evidence in literature? SUMMARY ANSWER The guideline development group formulated 84 recommendations answering 18 key questions stimulation. WHAT IS KNOWN ALREADY Ovarian stimulation for IVF/ICSI has been discussed briefly National Institute Health and Care Excellence fertility problems, Royal Australian New Zealand College Obstetricians Gynaecologist published a statement assisted...
Abstract STUDY QUESTION How should recurrent implantation failure (RIF) in patients undergoing ART be defined and managed? SUMMARY ANSWER This is the first ESHRE good practice recommendations paper providing a definition for RIF together with on how to investigate causes contributing factors, improve chances of pregnancy. WHAT IS KNOWN ALREADY challenge clinic, multitude investigations interventions offered applied clinical practice, often without biological rationale or unequivocal evidence...
Women with polycystic ovary syndrome (PCOS) are at risk of developing ovarian hyperstimulation (OHSS) during stimulation. Use GnRH antagonist in the general subfertile population is associated lower incidence OHSS than agonists and similar probability live birth but it unclear if this true for patients PCOS. Our aim was to compare flexible agonist long protocols PCOS undergoing IVF (primary end-point: ongoing pregnancy rate per patient randomized). In randomised controlled trial (RCT), 220...
STUDY QUESTIONWhat is the proper way of assessing effect progesterone elevation (PE) on day hCG live birth in women undergoing fresh embryo transfer after vitro fertilization (IVF) using GnRH analogues and gonadotrophins?
Is it possible to define a set of performance indicators (PIs) for clinical work in ART, which can create competency profiles clinicians and specific process steps?
Although initial studies in poor responders using GnRH antagonists have reported encouraging results, they are limited number, only a few of them prospective, while the majority is characterized by power to detect clinically important difference. A randomized controlled trial was performed patients with one or more previous failed IVF cycles which five less oocytes were retrieved, ≥300 IU gonadotrophins/day. Patients computer-generated list and treated either flare-up agonist protocol (n =...
STUDY QUESTIONDo live birth rates differ between modified natural cycles (MNCs) and using high-dose follicle stimulating hormone (HDFSH) with gonadotrophin-releasing (GnRH) antagonist in poor responder patients?
Management of established severe OHSS requires prolonged hospitalization, occasionally in intensive care units, accompanied by multiple ascites punctures, correction intravascular fluid volume and electrolyte imbalance. The aim the present study was to evaluate whether it is feasible manage women with as outpatients treating them GnRH antagonists luteal phase.This a single-centre, prospective, observational, cohort study. Forty patients diagnosed OHSS, five days post oocyte retrieval, were...
Are there any baseline predictors of progesterone elevation (PE) on the day human chorionic gonadotrophin (hCG) which are not associated with intensity ovarian stimulation in women undergoing vitro fertilization (IVF) using follicle stimulating hormone (FSH) and gonadotrophin-releasing (GnRH) antagonists? Basal (Day 2 menstrual cycle) serum concentration history PE variables that can predict occurrence hCG independently stimulation. is magnitude response to For this reason, it has been...
STUDY QUESTIONDo high-risk patients who develop severe early ovarian hyperstimulation syndrome (OHSS) and receive low-dose GnRH antagonist in the luteal phase have lower live birth rates compared with do not OHSS phase?
The purpose of the study was to assess ongoing pregnancy rates across groups patients treated by IVF, which were defined according criteria aimed at prevention premature LH surge and used for initiating GnRH antagonist.This is a prospective observational cohort study. During last 3 years, in IVF-ICSI undergoing controlled ovarian stimulation (COS) with antagonist protocol, administration initiated least one following patient-specific criteria: (i) follicle measuring >14 mm; (ii) estradiol...
The optimal time for GnRH antagonist initiation is still debatable. purpose of the current randomized controlled trial to provide endocrine and follicular data during ovarian stimulation IVF in patients with polycystic syndrome (PCOS) treated either a long agonist scheme or fixed day-1 protocol. Randomized both groups (antagonist: n = 26; agonist: 52) received oral contraceptive pill treatment three weeks starting dose 150 IU follitropin β. primary outcome was E2 level on Day 5 stimulation,...
Abstract STUDY QUESTION Does follicular flushing increase the number of cumulus–oocyte complexes (COCs) retrieved compared to single aspiration? SUMMARY ANSWER Follicular significantly increases COCs aspiration. WHAT IS KNOWN ALREADY On basis published meta-analyses, does not seem oocytes retrieved, probability clinical pregnancy, or that live birth and has been associated with an in duration oocyte retrieval. It should be noted, however, all eligible randomized controlled trials (RCTs)...
ABSTRACT Objective To assess ultrasound and hematological changes during the early luteal phase following triggering of final oocyte maturation with human chorionic gonadotropin (hCG) in women at high risk for developing ovarian hyperstimulation syndrome (OHSS). Methods This was a retrospective cohort study 319 undergoing in‐vitro fertilization who were OHSS administration hCG maturation. Patients treated gonadotropin‐releasing hormone agonist or antagonist protocol monitored 5 days...
The presence of smooth endoplasmic reticulum aggregates (SERa) in the ooplasm is considered as most severe oocyte dysmorphism due to its serious and potentially lethal outcomes offspring. In present case report, a couple underwent their first intracytoplasmic sperm injection (ICSI) cycle using gonadotrophin releasing hormone (GnRH) antagonist protocol, followed by fetal ultrasound scanning amniocentesis. SERa were observed all oocytes retrieved. A singleton pregnancy was established. second...