Lynn Sadler

ORCID: 0000-0003-0681-6652
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About
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Research Areas
  • Maternal and Perinatal Health Interventions
  • Birth, Development, and Health
  • Pregnancy and preeclampsia studies
  • Cervical Cancer and HPV Research
  • Maternal and fetal healthcare
  • Gestational Diabetes Research and Management
  • Assisted Reproductive Technology and Twin Pregnancy
  • Neonatal Respiratory Health Research
  • Global Maternal and Child Health
  • Endometriosis Research and Treatment
  • Gynecological conditions and treatments
  • Genital Health and Disease
  • Congenital Heart Disease Studies
  • Ovarian function and disorders
  • Pelvic floor disorders treatments
  • Endometrial and Cervical Cancer Treatments
  • Uterine Myomas and Treatments
  • Neonatal and fetal brain pathology
  • Reproductive Health and Contraception
  • Emergency and Acute Care Studies
  • Cardiovascular Issues in Pregnancy
  • Reproductive Health and Technologies
  • Reproductive System and Pregnancy
  • Preterm Birth and Chorioamnionitis
  • Global Cancer Incidence and Screening

Auckland City Hospital
2013-2025

Weatherford College
2004-2024

University of Auckland
2015-2024

Financial University
2024

Auckland District Health Board
2012-2024

Women's Health Research Institute
2019

Research Network (United States)
2018

RELX Group (United States)
2018

Women's Hospital
2002-2015

University of Manchester
2012

ContextIt is unclear whether treatments for cervical intraepithelial neoplasia (CIN) increase the subsequent risk of preterm delivery. Most studies have lacked sufficient sample size, mixed heterogeneous subtypes delivery, and failed to control confounding factors.ObjectiveTo determine laser loop electrosurgical excision procedure (LEEP) delivery its subtypes.Design, Setting, ParticipantsRetrospective cohort study conducted among women evaluated at a colposcopy clinic serving Auckland, New...

10.1001/jama.291.17.2100 article EN JAMA 2004-05-04

Endometrial scratching (with the use of a pipelle biopsy) is technique proposed to facilitate embryo implantation and increase probability pregnancy in women undergoing vitro fertilization (IVF).We conducted pragmatic, multicenter, open-label, randomized, controlled trial. Eligible were IVF (fresh-embryo or frozen-embryo transfer), with no recent exposure disruptive intrauterine instrumentation (e.g., hysteroscopy). Participants randomly assigned 1:1 ratio either endometrial (by biopsy...

10.1056/nejmoa1808737 article EN New England Journal of Medicine 2019-01-23

Objective To determine whether or not hysterectomy leads to an earlier onset of the menopause. Design A prospective cohort study. Setting Gynaecology service large urban hospital. Population Premenopausal women with and without hysterectomy. Methods Multivariate survival analysis techniques were used adjust for differences in initial follicle stimulating hormone (FSH) levels, body mass index, smoking unilateral oophorectomy between groups. Main outcome measures FSH levels measured five years...

10.1111/j.1471-0528.2005.00696.x article EN BJOG An International Journal of Obstetrics & Gynaecology 2005-05-23

Objectives Firstly, to compare pregnancy outcomes and cardiac complications in women with: 1. either mechanical or bioprosthetic valves at the mitral site; 2. treated with warfarin subcutaneous heparin. Secondly, determine aortic homograft valves. Design Historical cohort study. Setting Greenlane Hospital, Auckland, New Zealand. Population Young ( n = 255 ) who had valve replacements between 1972 1992. Seventy‐nine underwent 147 pregnancies. Main outcome measures Pregnancy loss,...

10.1111/j.1471-0528.2000.tb11696.x article EN BJOG An International Journal of Obstetrics & Gynaecology 2000-02-01

Screening for critical congenital heart disease (CHD) with prenatal ultrasound or postnatal pulse oximetry has the potential to improve outcome. To guide screening recommendations, this study aimed identify proportion and outcome of major CHD diagnosed before (early) after (late) discharge prior introduction screening.A retrospective, population-based review all in New Zealand from 2006 2010. The timing diagnosis relative intervention non-critical cases intention treat was determined, as...

10.1136/archdischild-2014-307691 article EN Archives of Disease in Childhood 2015-06-30

Background —The type of cardiac valve replacement associated with the lowest health risks for young women who may undergo pregnancies is unknown. We investigated which was greatest patient and survival effect pregnancy on loss. Methods Results —In this retrospective study, all 12 to 35 years old underwent replacements between 1972 1992 at Greenlane Hospital were identified, follow-up available in 93%. The 232 followed up 1499 patient-years. Ten-year mechanical (n=178), bioprosthetic (n=73),...

10.1161/01.cir.99.20.2669 article EN Circulation 1999-05-25

To compare maternal and neonatal outcomes in women with gestational diabetes treated diet, metformin and/or insulin routine clinical practice a single centre.We analysed prospectively collected data from the National Women's Health database for all who delivered between January 2007 December 2009. Since June 2007, requiring medication have been given choice of either or treatment, except fetal abdominal circumference less than 10th percentile, were not offered metformin.There 1269 diabetes;...

10.1111/j.1464-5491.2011.03361.x article EN Diabetic Medicine 2011-06-17

What proportion of clinicians across Australia, New Zealand and the UK are currently offering or recommending endometrial scratching for subfertility? Eighty-three percent responding to this survey women undergoing IVF. Endometrial is being proposed as a technique increase probability implantation in While trial results provide evidence favour procedure, there remains some uncertainty about both extent any beneficial effect subgroups most likely benefit. Cross-sectional with responses from...

10.1093/humrep/dew053 article EN Human Reproduction 2016-03-22
James MN Duffy G. David Adamson E A Benson Siladitya Bhattacharya Siladitya Bhattacharya and 95 more Magdalena Bofill Kate Brian Barbara Collura Cate Curtis J.L.H. Evers Roy G. Farquharson A Fincham Sebastian Franik Linda C. Giudice Elsa J. Glanville Martha Hickey Andrew W. Horne M. Louise Hull Neil Johnson Vanessa Jordan Yacoub Khalaf J.M.L. Knijnenburg Richard S. Legro Sarah Lensen James Mackenzie D. Mavrelos Ben W. Mol Dean E. Morbeck H Nagels Ernest Hung Yu Ng Craig Niederberger A.S. Otter Lucian Puşcaşiu Satu Rautakallio-Hokkanen Lynn Sadler Ippokratis Sarris Marian Showell Joshua D. Stewart Annika Strandell C. Strawbridge Andy Vail Madelon van Wely M. Vercoe Lan N. Vuong Alex Wang Rui Wang Jack Wilkinson KHF Wong Tien Yin Wong Cindy Farquhar Hisham Alahwany Ofra Balaban Faith Barton Yusuf Beebeejaun Jacky Boivin Jan Bosteels Carlos Calhaz–Jorge Arianna D’Angelo Leona F. Dann Christopher J. De Jonge Elyce du Mez Rui Alberto Ferriani Marie-Odile Gerval Lynda J. Gingel Ellen Greenblatt Geraldine Hartshorne Charlie Helliwell Charlotte Helliwell Lynda Hughes Junyoung Jo Jelena Jovanović Ludwig Kiesel Chumnan Kietpeerakool Elena Kostova Tansu Küçük Rajesh Kumar Robyn L. Lawrence Nicole Lee Katy E. Lindemann Olabisi Loto P. Lutjen Michelle MacKinven Mariano Mascarenhas Helen McLaughlin David J. Mills Selma Mourad Linh K. Nguyen Robert J. Norman Maja Olic Kristine L. Overfield Maria Parker-Harris David G. Ramos Aleksandra Rendulic Sjoerd Repping Roberta Rizzo Paola Salacone Catherine Saunders Rinku Sengupta Ioannis A. Sfontouris Natalie R. Silverman

Can the priorities for future research in infertility be identified?The top 10 four areas of male infertility, female and unexplained medically assisted reproduction ethics, access organization care people with fertility problems were identified.Many fundamental questions regarding prevention, management consequences remain unanswered. This is a barrier to improving received by those problems.Potential collated from an initial international survey, systematic review clinical practice...

10.1093/humrep/deaa242 article EN cc-by-nc Human Reproduction 2020-09-01
James MN Duffy Hisham Alahwany Siladitya Bhattacharya Barbara Collura Cate Curtis and 93 more J.L.H. Evers Roy G. Farquharson Sebastian Franik Linda C. Giudice Yacoub Khalaf J.M.L. Knijnenburg Brigitte Leeners Richard S. Legro Sarah Lensen Juan Carlos Vázquez-Niebla D. Mavrelos Ben W. Mol Craig Niederberger Ernest Hung Yu Ng A.S. Otter Lucian Puşcaşiu Satu Rautakallio-Hokkanen Sjoerd Repping Ippokratis Sarris Joe Leigh Simpson Annika Strandell C. Strawbridge Helen L. Torrance Andy Vail Madelon van Wely M. Vercoe Lan N. Vuong Alex Wang Rui Wang Jack Wilkinson Mohamed Youssef Cindy Farquhar Ahmed M Abou-Setta Juan J. Aguilera Oluseyi O.A. Atanda Eva Balkenende Kurt T. Barnhart Yusuf Beebeejaun Siladitya Bhattacharya Megan Black Magdalena Bofill Georgina M. Chambers Abrar Ahmad Chughtai Javier Crosby Irene Cuevas Arianna D'Angel Danielle D. Dubois Kirsten Duckitt Carlos García Encinas Anita Fincham Marie-Odile Gerval Nhu H. Giang Ahmed Gibreel Lynda J. Gingel Elizabeth Glanville Demián Glujovsky Ingrid Granne Georg Griesinger Devashana Gupta Zeinab Hamzehgardeshi Martha Hickey Martin Hirsch Marcos Horton M. Louise Hull Shikha Jain Marta J. Perez Claire Jones Vanessa Jordan Mohan S. Kamath Elena Kostova Antonio La Marca Tien Khac Le Arthur Leader Jian Li Olabisi Loto Karen L. Marks Alison McTavish David J. Mills R. Nair Dung Thi Phuong Nguyen Allan Pacey Lynn Sadler Peggy Sagle Juan-Enrique Schwarze Heather Shapiro Marian Showell Charalampos Siristatidis Akanksha Sood C. Tu Emma L. Votteler Chi Chiu Wang Andrew Watson Menem Yossry

Can a core outcome set to standardize selection, collection and reporting across future infertility research be developed?A minimum data set, known as has been developed for randomized controlled trials (RCTs) systematic reviews evaluating potential treatments infertility.Complex issues, including failure consider the perspectives of people with fertility problems when selecting outcomes, variations in definitions selective outcomes on basis statistical analysis, make results difficult...

10.1093/humrep/deaa241 article EN cc-by-nc Human Reproduction 2020-09-01

Objective To investigate associations of the Fetal Pillow® with maternal and neonatal morbidity. Design Retrospective cohort. Setting Two tertiary maternity units, New Zealand. Population or Sample Full dilatation singleton, term, cephalic caesarean section, three comparisons: at Unit A (1) before versus after introduction (1 Jaunary 2016–31 October 2021); (2) without (27 July 2017–31 (3) between B during same time period January 2019–31 2021). The is unavailable B. Methods Cases were...

10.1111/1471-0528.17772 article EN BJOG An International Journal of Obstetrics & Gynaecology 2024-01-29

10.1111/j.1471-0528.1995.tb09077.x article EN BJOG An International Journal of Obstetrics & Gynaecology 1995-02-01
James MN Duffy Siladitya Bhattacharya Siladitya Bhattacharya Magdalena Bofill Barbara Collura and 93 more Cate Curtis J.L.H. Evers Linda C. Giudice Roy G. Farquharson Sebastian Franik Martha Hickey M. Louise Hull Vanessa Jordan Yacoub Khalaf Richard S. Legro Sarah Lensen D. Mavrelos Ben W. Mol Craig Niederberger Ernest Hung Yu Ng Lucian Puşcaşiu Sjoerd Repping Ippokratis Sarris Marian Showell Annika Strandell Andy Vail Madelon van Wely M. Vercoe Lan N. Vuong A.Y. Wang Rui Wang Jack Wilkinson Mohamed Youssef Cindy Farquhar Ahmed M Abou-Setta Juan J. Aguilera Hisham Alahwany Oluseyi O.A. Atanda Eva Balkenende Kurt T. Barnhart Yusuf Beebeejaun Megan Black Georgina M. Chambers Abrar Ahmad Chughtai Javier Crosby Irene Cuevas Cate Curtis Arianna D’Angelo Danielle D. Dubois Kirsten Duckitt Carlos García Encinas Marie-Odile Gerval Nhu H. Giang Ahmed Gibreel Lynda J. Gingel Elizabeth Glanville Demián Glujovsky Ingrid Granne Georg Griesinger Devashana Gupta Repromed Zeinab Hamzehgardeshi Martin Hirsch Marcos Horton Shikha Jain Marta J. Perez Claire Jones Mohan S. Kamath J.M.L. Knijnenburg Elena Kostova Antonio La Marca Tien Khac Le Arthur Leader Brigitte Leeviers Jian Li Chinese Olabisi Loto Karen L. Marks Rodrigo M. Martinez-Vazquez Alison McTavish David J. Mills R. Nair Dung Thi Phuong Nguyen Anne-Sophie Otter Allan Pacey Satu Rautakallio-Hokkanen Lynn Sadler Peggy Sagle Juan-Enrique Schwarze Heather Shapiro Joe Leigh Simpson Charalampos Siristatidis Akanksha Sood C. Strawbridge Helen L. Torrance Cam Tu Tran Emma L. Votteler Chi Chiu Wang Andrew Watson Menem Yossry

Can consensus definitions for the core outcome set infertility be identified in order to recommend a standardized approach reporting?Consensus individual outcomes, contextual statements, and reporting table have been developed.Different exist outcomes infertility. This variation increases opportunities researchers engage with selective reporting, which undermines secondary research compromises clinical practice guideline development.Potential were by systematic review of definition...

10.1016/j.fertnstert.2020.11.013 article EN cc-by-nc-nd Fertility and Sterility 2020-11-30

Abstract Background The approach to induction of labour differs internationally, with timing amniotomy being controversial. Some institutions favour performing artificial rupture membranes prior commencement oxytocin infusion, the belief that will progress more efficiently. In other institutions, recommended is for infusion intact amniotic until person has reached active phase labour, citing risk infection early amniotomy. Current evidence inconclusive. We are a randomised controlled trial...

10.1186/s13063-025-08722-z article EN cc-by Trials 2025-01-22
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