- Glioma Diagnosis and Treatment
- Reproductive Biology and Fertility
- Assisted Reproductive Technology and Twin Pregnancy
- Ovarian function and disorders
- Vascular Malformations Diagnosis and Treatment
- Functional Brain Connectivity Studies
- Hemoglobin structure and function
- Advanced Neuroimaging Techniques and Applications
- Cancer Genomics and Diagnostics
- Protein Structure and Dynamics
- Neuroblastoma Research and Treatments
- Sarcoma Diagnosis and Treatment
- Prenatal Screening and Diagnostics
- Advanced NMR Techniques and Applications
- Chromatin Remodeling and Cancer
- Dental Erosion and Treatment
- Neurological Complications and Syndromes
- Intraoperative Neuromonitoring and Anesthetic Effects
- Organ and Tissue Transplantation Research
- Gynecological conditions and treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- Sulfur Compounds in Biology
- Neural dynamics and brain function
- Moyamoya disease diagnosis and treatment
- Effects of Radiation Exposure
Hospital de Dona Estefânia
2025
Centro Hospitalar de Vila Nova de Gaia
2024
Universidade do Porto
2024
National Statistical Institute of Portugal
2020
Centro Hospitalar do Baixo Vouga
2020
Instituto Politécnico de Lisboa
2015
University of Lisbon
2015
Valencian Infertility Institute
2006-2010
Universitat de València
2006
Universidade Nova de Lisboa
2002
Abstract The field of preimplantation genetic testing (PGT) is evolving fast, and best practice advice essential for regulation standardisation diagnostic testing. previous ESHRE guidelines on PGD, published in 2005 2011, are considered outdated, the development new papers outlining recommendations good PGT was necessary. current paper provides technical aspects embryo biopsy covers procedure, cryopreservation laboratory issues training, addition to strengths limitations specific currently...
The environment of the oocyte during its in vivo maturation consists follicular fluid (FF) and is surrounded by granulosa cells. FF derived from sanguineous plasma secretions, synthesised follicle wall, that contain a large variety growth factors, cytokines, amino acids, other metabolites. These metabolites are presumably involved physiology oocyte. identification, quantification study can provide additional information about state which be helpful distinguishing those oocytes have greater...
Abstract STUDY QUESTION How does a natural proliferative phase (NPP) strategy for frozen embryo transfer (FET) compare with the conventional artificial (AC) and (NC) endometrial preparation protocols in terms of live birth rates (LBR)? SUMMARY ANSWER This study supports hypothesis that, just as NC, NPP-FET may be superior alternative to AC LBR. WHAT IS KNOWN ALREADY Although FETs are increasing worldwide, optimal FET protocol is still largely controversial. Despite recent evidence supporting...
Do children born after vitrified-thawed embryo transfers (ETs) using donated oocytes have worse perinatal outcomes when compared with fresh ET?No significant difference in birthweight and prematurity rates between or frozen (FETs) newborns oocyte donation was found.Autologous singletons ET been previously associated higher of preterm birth low birthweight, while FETs seem to confer a risk hypertensive disorders during pregnancy macrosomia. However, studies comparing these autologous are...
The emergence of the coronavirus disease 2019 (COVID-19) pandemic severely compromised international travel and practice medicine. This study aimed to investigate evolution traveler behaviors prophylactic prescriptions across post-pandemic periods.
To demonstrate that the location of air bubble after embryo transfer (ET) does not necessarily indicate final location.Case report.Private clinic.A couple with primary infertility for whom a diagnosis bicornuate uterus very open angle between horns was confirmed.Laparoscopy and hysteroscopy were performed before an IVF cycle in which single replaced.Air image immediately ET gestational sac 3 weeks later.Immediately ET, seen left uterine horn. Three later, right horn.The location.
Abstract Study question How do natural proliferative phase for frozen embryo transfers (NPP-FET) compare to traditional artificial and cycle FETs in terms of pregnancy neonatal outcomes? Summary answer NPP-FETs were associated with similar ongoing rates after 22 weeks, but less miscarriage comparing cycles. What is known already The best FET protocol endometrial preparation still controversial. A (NC) may require more visits the clinic provides flexibility. Conversely, cycles (AC), although...
Parcellation of the brain into functionally meaningful regions is a crucial step in studies connectivity using complex network analysis methods based on resting-state functional MRI (rs-fMRI). With recent development fast acquisition sequences at ultra-high-field (7T), high-spatial-resolution rs-fMRI can now be collected from whole-brain with sufficient temporal resolution to capture slow haemodynamic fluctuations underlying connectivity. A method for obtaining individual parcel-lations has...
Desulfovibrio gigas desulforedoxin (Dx) consists of two identical peptides, each containing one [Fe-4S] center per monomer. Variants with different iron and zinc metal compositions arise when is produced recombinantly from Escherichia coli. The three forms the protein, homodimers [Fe(III)/Fe(III)]Dx [Zn(II)/Zn(II)]Dx, heterodimer [Fe(III)/Zn(II)]Dx, can be separated by ion exchange chromatography on basis their charge differences. Once separated, desulforedoxins reduced added dithionite. For...
(Abstracted from Hum Reprod 2024;39(5):1089–1097 Frozen embryo transfer (FET) use is increasing worldwide due to continuous cryopreservation technique improvements, reassuring safety data, and a growing list of indications. Different FET protocols include artificial (AC) natural cycle (NC), further exploration the efficacy these utmost importance.
Resistance to antiretroviral therapy is an increasing challenge in the management of HIV. We present case a woman living with HIV, history multiple treatment regimens and resistances antiretrovirals, who has been successfully treated combination lenacapavir fostemsavir for past year, obtaining undetectable viral load within one month starting reporting no serious side effects. This amongst first document combined use lenacapivir treating multidrug-resistant It supports potential these novel...
Resumo Numerosos estudos epidemiologicos na Europa e EUA mostraram uma associacao entre a trissomia 21 doenca celiaca. Objectivos: Caracterizar populacao de criancas com seguidas consulta do Centro Desenvolvimento da Crianca (CDC) Hospital Pediatrico Coimbra (HPC) quanto aos marcadores serologicos celiaca elaborar um protocolo actuacao. Metodologia: Avaliacao retrospectiva 120 Janeiro 1999 Marco 2003. Utilizando metodos estatistica descritiva foram analisadas as seguintes variaveis: factores...