A5074284134- Reproductive Biology and Fertility
- Ovarian function and disorders
- Reproductive Health and Technologies
- Assisted Reproductive Technology and Twin Pregnancy
- Sperm and Testicular Function
- Prenatal Screening and Diagnostics
- Seed Germination and Physiology
- Renal and related cancers
- Maternal and Neonatal Healthcare
- Tissue Engineering and Regenerative Medicine
- Reproductive System and Pregnancy
- Advanced Technologies in Various Fields
- Biological Control of Invasive Species
- Machine Learning in Healthcare
- Cardiac, Anesthesia and Surgical Outcomes
- Uterine Myomas and Treatments
- Birth, Development, and Health
- Urological Disorders and Treatments
- Endometriosis Research and Treatment
- Nausea and vomiting management
- Polymer Science and PVC
- Cancer Risks and Factors
- Enhanced Recovery After Surgery
Valencian Infertility Institute
2014-2024
Instituto de Investigación Sanitaria La Fe
2024
Universidad Católica de Santiago de Guayaquil
2023
RELX Group (United States)
2021
Instituto Valenciano de la Edificación
2021
Universitat de València
2003-2010
IVI Madrid Clinic
2008
Guardia Civil
2000
BACKGROUNDAn efficient oocyte cryopreservation method is mandatory to establish a successful egg-banking programme. Although there are increasing reports showing good clinical outcomes after cryopreservation, still lack of large controlled studies evaluating the effectiveness cryo-banking. In this study, we aimed compare outcome vitrified-banked oocytes with gold standard procedure employing fresh oocytes.
Is the indication for fertility preservation (FP) related to success in IVF cycles after elective-FP (EFP) age-related decline and FP before cancer treatment (Onco-FP)?Although rates were lower patients, there was no statistically significant association between malignant disease reproductive outcome correction age controlled-ovarian stimulation (COS) regime.FP is increasingly applied assisted reproduction, but little known about of with vitrified oocytes patients.Retrospective,...
An efficient method for cryopreservation of human oocytes may offer solutions to legal and ethical problems in routine infertility programs also be used fertility preservation medical social reasons.We conducted an observational longitudinal cohort multicentric study investigate the efficacy reproducibility oocyte outcomes IVF/ICSI cycles. Moreover, effects patient cycle characteristics on delivery rate (DR) were analyzed.In 486 cycles performed 450 couples, 2721 warmed 2304 them survived...
What progress has been made in fertility preservation (FP) over the last decade?FP techniques have widely adopted decade and therefore establishment of international registries on their short- long-term outcomes is strongly recommended.FP a fundamental issue for both males females whose future may be compromised. Reproductive capacity seriously affected by age, different medical conditions also treatments, especially those with gonadal toxicity. There general consensus need to provide...
Sperm vitrification (V) is a method for cryopreservation, without the use of conventional cryoprotectants, by plunging sperm suspension directly into liquid nitrogen (LN25).This study aimed to compare new system V with freezing (CF) protocol using fresh spermatozoa as reference (C).Prospective cohort study. A total 47 samples from men attending infertility clinic at Instituto Valenciano de Infertilidad Valencia. The solution was 0.3 M trehalose-sucrose and plunged in microdroplets 5-10 lL,...
Abstract Study question Can vitrification and warming procedures be executed efficiently with reduced exposure times to cryopreservation solutions? Summary answer Fast protocols demonstrated efficiency rates similar a standard protocol in all pre-clinical models tested significant reduction execution times. What is known already Vitrification an advanced technique well established protocols. However, these require considerable time workload the daily routine of IVF laboratories. Recent...
This study was carried out, first, to determine the feasibility of postoperative home care for three elective operations and, second, explore introducing as a more economical alternative following surgical procedures: herniorrhaphy, vaginal hysterectomy, and vein stripping. Clinical, environmental, operative, socioeconomic criteria were applied 487 outpatients which 44 pairs selected matched by age, sex, diagnosis, characteristics. Each member pair randomly assigned either hospital or care....
Study question: To compare the pregnancy rate in patients submitted to FET (Frozen Embryos Transfer) of cleavage stage embryos (Group 1), or at blastocyst 2).Summary answer: Our data showed that transfer frozen blastocysts has a better than embryos.What is known already: The first birth baby arising from cryopreserved embryo occurred 1983.Since then, improvements cryopreservation have occurred.However since early 90 ′ s vitrification technique also been developed cryopreserve any...
Abstract Study question Could Medroxyprogesterone Acetate (MPA) be a good alternative to gonadotropin-realeasing hormone (GnRH) antagonist in vitrified oocyte donation cycles? Summary answer MPA is GnRH cycles, ensuring comparable embryo quality and clinical outcome. What known already Progestin-primed ovarian stimulation (PPOS), such as oral administration the follicular phase appears an effective conventional protocols, it prevents premature LH surge hyperstimulation syndrome. The drawback...
Abstract Study question Does duration of storage affect clinical outcome in frozen embryo transfer (FET) cycles? Summary answer Long-term does not live birth rate (LBR) elective and non-elective FET cycles. What is known already Despite the success rates provided by vitrification programs, some studies found an association between cryo-storage decreased outcome, raising concern about potential negative effect that prolonged may have on embryos. design, size, This was a retrospective...
Abstract Study question Is it possible to predict the fetal heartbeat of frozen blastocysts from post-warming time-lapse images and videos captured with EmbryoScope? Summary answer A significant positive correlation was found between score given by artificial intelligence algorithm rate vitrified analyzed. What is known already Vitrification safest most successful technique for cryopreserving human embryos, although some best morphologically graded before freezing do not recover properly...
Abstract STUDY QUESTION Could an artificial intelligence (AI) algorithm predict fetal heartbeat from images of vitrified-warmed embryos? SUMMARY ANSWER Applying AI to blastocysts may help which ones will result in implantation failure early enough thaw another. WHAT IS KNOWN ALREADY The application the field embryology has already proven effective assessing quality fresh embryos. Therefore, it could also be useful outcome frozen embryo transfers, some do not recover their pre-vitrification...
Abstract Study question Do the Embryoscope and EmbryoscopePlus systems' built-in software evaluate differently embryos from vitrified or fresh oocytes? Summary answer The embryo scores provided by artificial intelligence (AI) algorithms are lower for originated vitrified/warmed oocytes than those that come oocytes. What is known already Time-lapse technology has enabled embryologists to develop several AI-based tools allow automation standardization of quality assessment. EmbryoScope...
Abstract Study question Does the post-warmed blastocyst dynamics have an impact over likelihood of achieving a live birth? Summary answer Variables related to vitrified/warmed blastocysts shown greater effect on birth prediction than only embryo morphological quality through artificial intelligence. What is known already Morphological were described by Coello et al., in 2017. The investigated markers thickness zona pellucida (µm) and area (µm2) after warming before transfer, inner cell mass...