A5022118127- Reproductive Biology and Fertility
- Prenatal Screening and Diagnostics
- Assisted Reproductive Technology and Twin Pregnancy
- Ovarian function and disorders
- Reproductive Health and Technologies
- Reproductive System and Pregnancy
- Ectopic Pregnancy Diagnosis and Management
- Renal and related cancers
- Pluripotent Stem Cells Research
- Sperm and Testicular Function
- Vitamin D Research Studies
- Magnetic and Electromagnetic Effects
- Endometriosis Research and Treatment
- Reproductive Health and Contraception
- Sexual Differentiation and Disorders
- CRISPR and Genetic Engineering
- Mitochondrial Function and Pathology
- Genetics, Aging, and Longevity in Model Organisms
- Genetic Syndromes and Imprinting
- Gynecological conditions and treatments
- Intestinal and Peritoneal Adhesions
Universidad de Alcalá
2021-2024
IVI Middle East Fertility Clinic
2017-2023
Emirates Foundation
2021-2022
Abstract STUDY QUESTION What are the clinical pregnancy and live birth rates in women who underwent up to two more euploid blastocyst transfers after three failures absence of another known factor that affects implantation? SUMMARY ANSWER The fourth fifth resulted similar 40% 53.3%, respectively, culminating a cumulative rate 98.1% (95% CI = 96.5–99.6%) five transfers. WHAT IS KNOWN ALREADY first blastocysts have implantation provide 92.6%. DESIGN, SIZE, DURATION An international...
Abstract STUDY QUESTION Does the insemination method impact euploidy outcome in couples with non-male factor infertility? SUMMARY ANSWER Conventional IVF can be applied cycles preimplantation genetic testing for aneuploidies (PGT-A), as both and ICSI generate equal numbers of euploid blastocysts. WHAT IS KNOWN ALREADY Ever since its introduction, popularity has increased tremendously, even infertility. The use conventional is a contraindication undergoing PGT to ensure monospermic...
How reliable are cleavage stage and trophectoderm (TE) biopsies compared to inner cell mass (ICM) biopsies?The reliability of TE biopsy ICM is almost perfect, but only substantial between biopsy.One the prevailing reasons for implantation failure presumed be chromosomal aneuploidy in human preimplantation embryos. Preimplantation genetic testing aneuploidies (PGT-A) has been introduced into assisted reproduction an effort increase pregnancy rates. Increasing evidence indicates that results...
Objective This study aimed to analyze the morphokinetic behaviour between conventional IVF and ICSI, in cycles with preimplantation genetic testing for aneuploidies (PGT-A). Materials A randomized controlled trial (NCT03708991) was conducted a private fertility center. Thirty couples non-male factor infertility were recruited November 2018 April 2019. total of 568 sibling cumulus oocyte complexes randomly inseminated ICSI cultured an Embryoscope time-lapse system. The IVF/ICSI oocytes...
One of the most important limitations genetic testing in preimplantation embryos is embryonic mosaicism, especially when performed on D3 with only a single blastomere evaluated. Previous publications, using Array-Comparative Genomic Hybridization (a-CGH) to compare day 3 (D3) biopsies versus trophectoderm for analysis aneuploid embryos, showed similar high concordance rates per embryo diagnosis and biopsies. Next generation sequencing (NGS) was introduced lately as new technique aneuploidies...
Context The widespread distribution of the Vitamin D (VitD) receptor in reproductive tissues suggests an important role for VitD human reproduction. assessment patient´s is based on 25-hydroxyvitamin (25(OH)D) metabolite measurement. However, most circulating 25(OH)D bound to either VitD-binding protein (VDBP) (88%) or albumin (12%) and less than 1% circulates free. Objective To determine a possible correlation between levels serum (S) follicular fluid (FF) blastocyst ploidy status patients...
Background Anti-Müllerian hormone (AMH) and antral follicle count (AFC) age-specific reference values form the basis of infertility treatments, yet they were based upon studies performed primarily on Caucasian populations. However, may vary across different age-matched ethnic This study aimed to describe serum AMH AFC for women native Arabian Peninsula. Methods A retrospective large-scale was including 2,495 women, aged 19 50 years, measured as part their fertility assessment at...
(Abstracted from Hum Reprod 2024;39(5):974–980 Recurrent implant failure (RIF) has been defined as repeated failed implantations following multiple embryo transfers. A landmark paper on RIF reported the cumulative sustained implantation and live birth rates achieved with 3 consecutive single euploid blastocyst transfers found a similar rate across first “true” unexplained of <5% in vitro fertilization population.
Objective . To report the arrest of euploid embryos with high mtDNA content. Design A 2 cases. Setting Private fertility clinic. Patients patients, 45 and 40 years old undergoing IVF treatment. Interventions Mature oocytes were collected vitrified from two ovarian stimulations. Postthaw, survived mature underwent fertilization by intracytoplasmic sperm injection (ICSI). Preimplantation genetic screening (PGS) mitochondrial DNA (mtDNA) copy number done using next generation sequencing (NGS)....
The aim was to study whether a limited exposure of embryos outside the incubator has an effect on embryo development, blastocyst quality and euploid outcomes. This retrospective performed at ART Fertility Clinics, Abu Dhabi, United Arab Emirates (UAE) between March 2018 April 2020 included 796 mature sibling oocytes that were split randomly two incubators after intracytoplasmic sperm injection (ICSI): EmbryoScope™ (ES) benchtop incubator, G185 K-SYSTEMS (KS). fertilization, cleavage,...