A5029456307- GABA and Rice Research
- Diet, Metabolism, and Disease
- Bioactive Compounds and Antitumor Agents
- Metabolism, Diabetes, and Cancer
- Liver Disease Diagnosis and Treatment
- Natural Antidiabetic Agents Studies
- Cannabis and Cannabinoid Research
- Phytochemicals and Antioxidant Activities
- Fungal Biology and Applications
- Autoimmune Bullous Skin Diseases
- Essential Oils and Antimicrobial Activity
- Curcumin's Biomedical Applications
- Cell death mechanisms and regulation
- Genomics, phytochemicals, and oxidative stress
- Phytochemicals and Medicinal Plants
- PARP inhibition in cancer therapy
- Adipokines, Inflammation, and Metabolic Diseases
- Cholinesterase and Neurodegenerative Diseases
- Bioactive natural compounds
- Adipose Tissue and Metabolism
- Nail Diseases and Treatments
- Synthesis of Organic Compounds
- Tannin, Tannase and Anticancer Activities
Prince of Songkla University
2022-2025
This study aimed to explore the use of D-limonene and some vegetable oils with different amounts saturated unsaturated fatty acids as alternative green solvents for microwave-assisted extraction (MAE) cannabis (Cannabis sativa L.). A standardized extract was selected evaluate its potential a chemopreventive agent. Alternative solvents, powder-to-solvent ratios, irradiation cycles were determined optimize MAE conditions. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay...
Hawm Gra Dang Ngah rice (HDNR) is a red variety cultivated in Thailand's southern border region, yet its biological properties have not been extensively studied. This study investigates the effects of HDNR extracts on bioactive constituents, spectral fingerprints, and antioxidant capacities. We evaluated inhibitory aqueous (HDNR-W) ethanolic (HDNR-E) monoamine oxidase (MAO), α-glucosidase, HMG-CoA reductase activities, as well their cytotoxicity normal cancer cells. The results demonstrated...
Our previous study has shown the beneficial effect of ethanolic extract Sangyod rice (SE) on lipid accumulation and insulin resistance. However, its vascular inflammation yet to be explored. The current aimed investigate anti‐inflammatory effects SE in both vitro vivo models, specifically examining impact LPS‐induced RAW264.7 cells evaluating efficacy an animal model diabetes mellitus induced by a high‐fat diet combined with low‐dose streptozotocin. In experiments, treatment effectively...
Two major cannabinoids of cannabis, namely cannabidiol (CBD) and tetrahydrocannabinol (THC) have been reportedly used as alternative medicine for diabetes treatment in both pre-clinical clinical research. However, their mechanisms action still remain unclear. Therefore, this study aimed to evaluate the α-glucosidase inhibitory activity THC, CBD standardized cannabinoid extracts. Based on silico studies, THC generated hydrogen bonding Van der Waals interactions, while exhibited only...
This study aimed to evaluate Sangyod rice extract (SRE) in two aspects: its effect on 3T3-L1 cell proliferation during early adipocyte differentiation and anti-adipogenic properties. Initially, SRE reduced preadipocyte by downregulating mTOR Akt expression. In later stages, it significantly inhibited adipogenesis, lowering lipid accumulation triglyceride levels. achieved these effects suppressing key adipogenic transcription factors (PPAR-γ, C/EBPα, C/EBPβ, SREBP-1c, SREBP-2) lipogenic genes...
Background: Since cannabis has been legally allowed for medicinal purposes in many countries, it become the most interesting issue, particularly neurologic disorders, such as Alzheimer’s disease (AD). Inhibition of acetylcholinesterase (AChE) is one mechanisms treatment AD. Objectives: The present study aimed to establish a method preparation cannabinoid-rich extracts and determine their AChE inhibitory activity. Methods: were prepared through green extraction process using...
α-Mangostin-rich extract (AME) shows promise as a functional ingredient for cancer chemotherapy. Here, we encapsulated AME in our originally designed antioxidant nanoparticles (NanoAOX) to increase its solubility and prevent oxidative degradation (AME@NanoAOX). In this study, two types of self-assembled polymers containing nitroxide radicals were engineered. These into nanoscale particles aqueous media, entrapping (abbreviated AME@NanoAOX(B) AME@NanoAOX(G)). formulations considerably...