A5007091486- Atmospheric chemistry and aerosols
- Wound Healing and Treatments
- Diabetic Foot Ulcer Assessment and Management
- Renal and related cancers
- Renal cell carcinoma treatment
- Reconstructive Surgery and Microvascular Techniques
- Pressure Ulcer Prevention and Management
- Lymphatic System and Diseases
- Air Quality and Health Impacts
- Facial Rejuvenation and Surgery Techniques
- Mesenchymal stem cell research
- Dermatologic Treatments and Research
- Reconstructive Facial Surgery Techniques
- Vehicle emissions and performance
- Atmospheric aerosols and clouds
- Nasal Surgery and Airway Studies
- Environmental Policies and Emissions
- Botulinum Toxin and Related Neurological Disorders
- Sinusitis and nasal conditions
- Bladder and Urothelial Cancer Treatments
- Atmospheric Ozone and Climate
- Sympathectomy and Hyperhidrosis Treatments
- Diagnosis and Treatment of Venous Diseases
- Bone fractures and treatments
- Renal Transplantation Outcomes and Treatments
Korea University
2013-2025
Seoul National University Hospital
2013-2025
Korea University Medical Center
2017-2024
Christie's
2024
Seoul National University
2003-2023
National University College
2010-2022
New Generation University College
2010-2022
Weatherford College
2021
Ansan University
2012
Korea Institute of Science and Technology
1998-2009
Dual-modal in vivo tumor imaging and photodynamic therapy using hexagonal NaYF4:Yb,Er/NaGdF4 core–shell upconverting nanoparticles combined with a photosensitizer, chlorin e6, is reported. Tumors can be clearly observed not only the upconversion luminescence image but also magnetic resonance image. In by systemic administration demonstrated under 980 nm irradiation. Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents peer-reviewed,...
Accurate analysis of specific biomarkers in clinical serum is essential for early diagnosis and treatment cancer. Here, a surface-enhanced Raman scattering (SERS)-based immunoassay, using magnetic beads SERS nano tags, was developed the determination free to total (f/t) prostate antigen (PSA) ratio improve diagnostic performance To assess applicability proposed method, SERS-based assays simultaneous detection dual PSA markers, (f-PSA) complexed (c-PSA), were performed samples gray zone...
Mesenchymal stem cells (MSCs) may hold great promise for treating diabetic wounds. However, it is difficult a clinician to use MSCs because they have not been commercialized. Meanwhile, new commercial drug that contains adipose-derived (ASCs) has developed. The purpose of this study was examine the potential allogeneic ASC sheets foot ulcers. Fifty-nine patients with ulcers were randomized either treatment group (n = 30) or control treated polyurethane film 29). Either an sheet applied on...
Wide variation in tacrolimus concentrations and low exposure have been reported to be associated with poor renal graft outcomes non-Asians. The CYP3A5 polymorphism is a representative genetic factor that might affect this association, together environmental factors. We investigated whether variability or the mean trough concentration can influence kidney allograft Asians (rs776746) relationship.Data from transplant patients between 2000 2010 were analyzed retrospectively. intraindividual...
Background. Tacrolimus is a major immunosuppressant, which has narrow therapeutic range and wide interindividual variation. The effects of genetic polymorphisms cytochrome P450 3A (CYP3A) 5 Adenosine triphosphate-binding cassette subfamily B member 1 (ABCB1) genes on the achievement target tacrolimus trough levels clinical outcomes in renal transplants were evaluated. Methods. A total 62 patients participated this prospective study. After an initial fixed oral dose (0.08 mg/kg two times per...
Beneficial effects of human adipose-derived stromal vascular fraction (SVF) cell injection on microcirculation have been recently reported in vitro and vivo studies. However, no clinical studies its effect diabetic patients who commonly experience compromised tissue perfusion, regardless the status intravascular blood flow. The present piloting study was designed to clinically examine possibility SVF accelerate microcirculation, particularly ischemic feet.Ten feet were included receive...
Our group has previously demonstrated that tissue-engineered dermis containing cultured fibroblasts or adipose-derived stromal vascular fraction cells is superior to artificial in terms of scar quality for covering facial defects. However, using these clinical applications requires Food and Drug Administration approval involves complex procedures cell culture isolation. This retrospective study aimed compare effects micronized adipose tissue (MAT) reconstruction. Tissue-engineered consisting...
Abstract Background: Prostate cancer is the most prevalent malignancy in men worldwide. However, absence of reliable biomarkers for metastasis due to intra- and inter-tumor heterogeneity complicates establishment personalized treatment guidelines. To address tumor heterogeneity, a next-generation sequencing (NGS)-based multigene assay, including gene expression, tumor-related pathways fusion variants, proposed developing new assay. This study aims develop validate risk prediction model...
The degradation of n-type and p-type low-temperature polycrystalline silicon (poly-Si) thin-film transistors (TFTs) due to hot-carrier stress was investigated by capacitance-voltage (C-V) measurement. In C-V measurements, the fixed charges in gate oxide TFTs are not affected a small-applied signal, whereas trap states bandgap respond applied frequency, so that dominant mechanism poly-Si can be evaluated. capacitance (C/sub GS/) between source gate, as well GD/) drain were measured....
Gaseous species and total suspended particles were measured at Kosan, Cheju Island, Korea, between 11 March 19 April 1994. The concentrations of nonsea salt (nss) ions higher than those in clean marine areas Japan other background the world. In particular, nss sulfate concentration was comparable to that Seoul. average SO2 NOx approximately 0.97 3.5 ppb, respectively, which lower urban Korea but remote contrast, O3 55 is or sites influenced by long-range transport air pollutants. Half...
Utilisation des proprietes electrostatiques pour capter les particules emises par un moteur diesel
To address whether napsin A is useful for identifying metastatic adenocarcinomas of pulmonary origin.Fifty-four cases adenocarcinoma that metastasized from the lungs to various sites and 1762 carcinoma organs were immunostained A, TTF-1, CK7, CK20 CDX2 using tissue microarray. The expression patterns TTF-1 in compared with matched primary lung tumours. Napsin expressed 87.0% 81.5% adenocarcinomas, respectively. Although there was no significant difference positivity as a single marker scores...
Extrapulmonary neuroendocrine carcinomas (EP-NECs) are associated with a poor clinical outcome, and limited information is available on the biology treatment of EP-NECs. We studied EP-NECs by applying recent novel findings from studies pulmonary carcinomas, including POU2F3, master regulator tuft cell variant small lung carcinomas. A cohort 190 patients surgically resected or poorly differentiated (PDCs) were established. Immunohistochemistry (IHC) for POU2F3 along ASCL1, NEUROD1, YAP1,...
Aging is a biologic process characterized by time-dependent functional declines that are influenced oxidative stress-induced inflammatory reactions. In particular, ultraviolet (UV) irradiation plays key role in cellular senescence photo-aged skin. However, the of epidermal keratinocytes and dermal fibroblasts UV may differ depending on exposure time dosage irradiation. Therefore, purpose study was to evaluate compare effects human (HaCaT) (HDFs). After cell viability test, 200 mJ/cm used...
OBJECTIVE. The purpose of this study was to compare the MDCT features renal cell carcinoma (RCC) associated with Xp11.2 translocation and TFE3 gene fusion (Xp11 RCC) papillary RCC. MATERIALS AND METHODS. included 19 39 patients histologically proven Xp11 RCC RCC, respectively, who underwent multiphase before nephrectomy. CT findings were compared between using Student t test chi-square test. Subgroup analyses small (< 4 cm) masses for these performed. RESULTS. Patients younger (p < 0.001),...
Primary renal well-differentiated neuroendocrine tumors (WDNETs) also called carcinoid and atypical are extremely rare, little is known about parameters that may predict prognosis at diagnosis. Six cases of primary WDNET were collected. After reviewing slides stained with hematoxylin eosin, proportions each growth pattern determined. Synaptophysin, chromogranin, CD56, Ki-67 immunostaining morphometric analysis performed. Patients included three female males, mean age was 53.3 years. The...
To reduce the morbidity and mortality of candidemia patients through rapid treatment, development a simple, molecular diagnostic method that is based on nucleic acid extraction superior to conventional methods for detecting Candida in blood necessary. We developed multiplex Pan/internal control (IC) loop-mediated isothermal amplification (LAMP) assay simple DNA boiling protocol using Chelex-100 could extract yeast within 20 min. The Chelex-100/boiling showed comparable efficiency commercial...