- Ovarian cancer diagnosis and treatment
- Sarcoma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Endometrial and Cervical Cancer Treatments
- Oral and Maxillofacial Pathology
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Urologic and reproductive health conditions
- Urinary and Genital Oncology Studies
- Endometriosis Research and Treatment
- Reproductive System and Pregnancy
- Cervical Cancer and HPV Research
- Skin and Cellular Biology Research
- Genital Health and Disease
- Medical Imaging and Pathology Studies
- Soft tissue tumors and treatment
- Bone health and treatments
- Cancer Diagnosis and Treatment
- Urological Disorders and Treatments
- Head and Neck Surgical Oncology
- Dermatological and Skeletal Disorders
- Tendon Structure and Treatment
- Cancer and Skin Lesions
- Cutaneous Melanoma Detection and Management
- Genetic and rare skin diseases.
Istanbul Medipol University
2016-2025
Kocaeli Üniversitesi
2010-2023
Women’s Health Care
2017
Hacettepe University
2017
Liv Hospital
2016
Dumlupinar University
2016
Antalya Bilim University
2016
Başkent University
2016
Çankırı Karatekin University
2016
Yahoo (United Kingdom)
2014
Background and Objectives: Epithelial ovarian cancer (EOC) remains a significant global health challenge. While traditional prognostic factors are well established, emerging biomarkers continue to gain attention. Materials Methods: This retrospective study evaluated the impact of systemic inflammatory markers on progression-free survival (PFS) overall (OS) in 154 EOC patients. Pre-treatment neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte (PLR), index (SII) were calculated categorized...
Background We aimed to evaluate the relationship between perineural invasion (PNI) and bone metastasis in prostate cancer (PCa). Methods retrospectively reviewed data of 633 PCas who had whole‐body scan (WBBS) 2008 2014. recorded age, clinical T‐stage, total PSA (tPSA) prior biopsy, Gleason sum (GS), PNI transrectal ultrasound guided biopsy (TRUS‐Bx) digital rectal examination findings. Bone metastases were assessed with WBBS magnetic resonance image if was suspicious. divided patients into...
The aim of this study was to determine the effects mesenchymal stem cell (MSC) application and possible pathways MSC's on tendon strength healing after repair.The included 40 Wistar albino rats. Mesenchymal cells were obtained from femurs tibias 6 Achilles tendons remaining 34 rats cut repaired with open surgical procedures. Rats divided into 2 groups. Percutaneous MSCs applied group (n=17) physiological serum only control at 4th week. sacrificed using cervical dislocation method under ether...
Giant cell tumor of the bone (GCTB) is usually a benign, locally aggressive with metastatic potential. Histogenesis GCTB unknown and correlation has not been found between histologic clinical course. For this reason, many authors consider its prognosis unpredictable. Lung metastasis after treatment well known generally unfavorable outcome, despite varied chemotherapy regimens. Denosumab, which inhibits RANK-RANKL interaction, new, promising actor among targeted therapeutic agents for GCTB....
To understand the role of epidermal cells in pathogenesis lichen amyloidosus (LA) and macular amyloidosis (MA).We carried out immunohistochemical investigations on cytokeratins (CKs) amyloid deposits formalin-fixed paraffin-embedded tissue specimens from eight persons with LA 12 MA. The primary antibodies CK1-8 (AE3), CK10 (DEK-10), CK14 (LL002), CK17 (E3), CK18 (DC10), CK19 (KS19.1), CK5/6/18 (LP34) CK8/18 (5D3) were used study.In deposits, immunoreactivity only two monoclonal (CK1-8...
Both clinically and histopathologically, melanoma of childhood is a rarely encountered lesion. In addition, it has particular histopathologic diagnostic problems. Differential diagnosis this lesion Spitz nevus at times very problematic, in that distant metastases death the patient may be only criteria for some cases. We present 4‐year‐old girl with an atypical melanocytic neoplasm Spitzoid features on left subscapular region.
The biological mechanisms of cancer and associations with behavior tumours need to be studied understand progression determine appropriate treatments. Here we investigated expression VEGF, MMP-9 E-cadherin in laryngeal SCCs their relations clinical behavior. This prospective study was based on 38 surgical specimens from patients primary SCC data recorded cards. Expression the three factors tumor tissue examined using immunohistochemistry correlations parameters tumors, regional lymph node...
We present a case of 40-yr-old woman diagnosed with primary malignant struma ovarii. The patient was admitted the complaint pelvic pain and large mass in mid-portion lower abdomen on gynecological examination. Pre-operative tumor markers routine biochemistry were unremarkable. She treated total abdominal hysterectomy right salpingo-oopherectomy. Post-operatively, she ovarii through usage histopathological criteria similar to guidelines for thyroid gland disease. subsequently performed left...
Idiopathic granulomatous mastitis (IGM) is a benign, inflammatory breast disease of unknown etiology. Although it rare, frequently presents in manner similar to that carcinoma.A 41-year-old female developed unilateral idiopathic mastitis, diagnosed by fine needle aspiration cytology. The clinical presentation and mammographic findings were suspicious for carcinoma. Fine cytology showed inflammation. Histopathologic examination revealed noncaseating, lesion. Further clinical, radiologic...
Synovial sarcoma (SS) is a highly malignant tumor that accounts for 10% of all soft-tissue sarcomas. Primary SS arising from the lung extremely rare, and prognosis poor. We report case pulmonary presenting with mass lesion invading right upper middle lobes, extending to mediastinum chest wall. After tru-cut biopsy, surgical resection was performed. The final diagnosis (biphasic type) based on histological immunohistochemical findings. There are no guidelines optimal treatment due rarity...
Ovotesticular disorder of sexual development (DSD) is characterized by the presence both ovarian and testicular tissues in same individual. The most common karyotype 46,XX. Here, we report case a boy with 46,XX/47,XXY diagnosed as ovotesticular DSD gonadal biopsy. A 5-month-old presented hypospadias, unilateral cryptorchidism, micropenis. Pelvic magnetic resonance imaging revealed suspicious gonad tissue that solid structure right scrotum cystic left inguinal canal. He underwent diagnostic...
Abdominal wall desmoid tumours (DT) are rare, slow-growing benign muscular-aponeurotic fibrous with the tendency to locally invade and recur. They constitute 0.03% of all neoplasms high infiltration recurrence rate, but there is no metastatic potential. Although surgery primary treatment modality, optimal remains unclear. endometriosis also an unusual disease, preoperative clinical diagnosis not always easy. The radiologic imaging modalities may aid time. Herein, we report abdominal mass...
The aim of this study was to compare the compatibility Alloderm, Dacron, Gore-Tex, and autologous cartilage graft materials with host tissues in nasal septal perforation repair surgery.The were placed into septum 16 New Zealand rabbits. At end 3rd month, septums rabbits removed totally reactions, such as inflammation;foreign body giant cell; or fibrosis that developed surrounding tissue against implant material evaluated.Acute inflammation reactions occurred mostly Gore-Tex. There no...