A5100926143- Acute Myeloid Leukemia Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Chronic Myeloid Leukemia Treatments
- Chronic Lymphocytic Leukemia Research
- Genomic variations and chromosomal abnormalities
- Immunotherapy and Immune Responses
- Viral Infections and Outbreaks Research
- Immune Cell Function and Interaction
- Glycosylation and Glycoproteins Research
- SARS-CoV-2 and COVID-19 Research
- Telomeres, Telomerase, and Senescence
- Respiratory Support and Mechanisms
- Vaccine Coverage and Hesitancy
- RNA Interference and Gene Delivery
- Acute Lymphoblastic Leukemia research
- Animal Virus Infections Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Crystallization and Solubility Studies
- Viral Infections and Vectors
- RNA regulation and disease
- Multiple Myeloma Research and Treatments
- Drug-Induced Ocular Toxicity
- Cancer-related Molecular Pathways
- Retinoids in leukemia and cellular processes
- T-cell and Retrovirus Studies
Fujian Agriculture and Forestry University
2025
First Affiliated Hospital of Guangzhou Medical University
2024
State Key Laboratory of Respiratory Disease
2016-2024
Guangzhou Medical University
2024
Anhui Medical University
2023
Center for Disease Control
2022-2023
Guangdong University of Technology
2020-2023
Henan Cancer Hospital
2004-2020
Zhengzhou University
2013-2020
Zhengzhou Central Hospital
2011
Green innovation in heavily polluting firms is crucial for sustainable development, yet financial constraints remain a major barrier. This study employs Spatial Durbin Model to analyze how financialization influences green China’s A-share listed firms. The results indicate that intensifies financing constraints, leading suppression of innovation. effect primarily driven by the “crowding-out effect”, which outweighs “reservoir effect” may provide. Additionally, industry-wide peer effects...
Chromosomal aberrations are useful in assessing treatment options and clinical outcomes of acute myeloid leukemia (AML) patients. However, 40 ∼ 50% the AML patients showed no chromosomal abnormalities, i.e., with normal cytogenetics aka CN-AML Testing molecular such as FLT3 or NPM1 can help to define but various successes. Goal this study was test possibility Wilms' tumor 1 (WT1) gene overexpression an additional biomarker. A total 103 patients, among which 28% had overexpressed WT1, were...
Real-world evidence on the effectiveness of COVID-19 vaccines marketed in China against Omicron BA.2.2 variant remains scarce. A case–control study was conducted to estimate vaccine (VE) (inactivated vaccines, an Ad5-nCoV vaccine, and a recombinant protein vaccine). There were 414 cases infected with SARS-CoV-2 828 close contacts whose test results consecutively negative as controls during outbreak Lu'an City, Anhui Province, China, April 2022. The overall adjusted VE infection vaccinated...
A semiconducting metal–organic crystalline nanotube array (MO-CNA) was constructed by the induction of Pb⋯S secondary interactions, exhibiting highly selective and sensitive NO 2 sensing with a low limit detection.
Background: To determine the seroprevalence, latent infection rate and risk factors for severe fever with thrombocytopenia syndrome virus (SFTSV) infection, a cross-sectional study was conducted in general population of Western region Anhui Province China from 1 September to 31 December 2014.Methods: Twelve villages highest rates endemic SFTS were selected six towns two counties western Province. Blood samples collected tested presence SFTSV-IgG antibodies by ELISA. Each participant...
BCR-ABL1 fusion proteins contain constitutively active tyrosine kinases that are potential candidates for targeted therapy with kinase inhibitors such as imatinib in chronic myeloid leukemia (CML). However, uncharacterized genes can be missed by quantitative RT-PCR (qRT-PCR)-based routine screening methods, causing adverse effect on drug selection and treatment outcome. In this study, we demonstrated the next-generation sequencing (NGS) employed to overcome obstacle. Through NGS, identified...
Fusion genes generated from chromosomal translocation play an important role in hematological malignancies. Detection of fusion currently employ use either conventional RT-PCR methods or fluorescent situ hybridization (FISH), where both involve tedious methodologies and require prior characterization events as determined by cytogenetic analysis. In this study, we describe a real-time quantitative reverse transcription PCR (qRT-PCR)-based multi-fusion gene screening method with the capacity...
Hubei province in China has had the most confirmed coronavirus disease 2019 (COVID-19) cases and reported sustained transmission of disease. Although Lu'an city is adjacent to province, its community was blocked at early stage, impact epidemic limited. Therefore, we summarised overall characteristics entire course help cities with a few imported better contain epidemic. A total 69 COVID-19 11 asymptomatic carriers were identified during from 12 January 21 February 2020. Fifty-two (65.0%)...
Elevated red blood cell distribution width (RDW) and decreased hematocrit (HCT) levels are associated with poor prognosis in chronic obstructive pulmonary disease (COPD) patients, but their significance intensive care unit (ICU) patients acute exacerbation of COPD (AECOPD) remains uncertain. The RDW/HCT ratio may offer a more comprehensive assessment compared to individual markers, potentially enhancing prognostic accuracy. Furthermore, the utility improving traditional ICU scoring systems...
The blood urea nitrogen/creatinine ratio (BCR) is an effective marker for disease severity stratification. Its efficacy has been demonstrated under numerous conditions. This study aims to investigate the relationship between BCR and in-hospital mortality in intensive care unit (ICU) patients with acute exacerbation of chronic obstructive pulmonary (AECOPD). Eligible ICU AECOPD from eICU database were included study. Patients divided into high-BCR low-BCR groups on basis optimal cutoff value...
This study was aimed to evaluate the frequencies and prognostic significance of nucleophosmin 1 (NPM1) mutation, fms-like tyrosine kinase 3 (FLT3) mutation c-KIT in acute myeloid leukemia (AML) explore their relevance clinical characteristics, cytogenetics survival. Genomic DNA from 78 newly diagnosed AML August 2010 October 2012 screened by PCR sequencing or capillary electrophoresis (CE) for NPM1, FLT3 mutations. The results showed that incidence NPM1 14.1% patients 26.7% normal karyotype...
To explore the clinical features and survival of patients with CD56 expression in de- novo acute myeloid leukemia（AML）with t（8;21). .Clinical data 82 de AML t（8;21）who were newly diagnosed from Jan 2008 to Apr 2014 analyzed retrospectively, 50 expressed 32 not. Clinical characteristics prognoses compared between expressing nonexpressing CD56.There no statistically significant differences terms age, gender, white blood cell count（WBC）, percentage bone marrow blasts, extramedullary...
Objective Assessment of the clinical application pulmonary rehabilitation in China. Methods Using questionnaires link on WeChat group and Breathing BBS. Results 314 327 were valid questionnaires.The perfect rate large (provincial or municipal) hospitals small (county )hospitals 13.78% (35/254) 2.00% (1/50), carried out but imperfect 57.87%(147/254)and 42.00%(21/50), ready to carry respectively 20.87% (53/254) 26.00% (13/50), no rehabilitation′ 7.48% (19/254) 30.00% (15/50),...
Objective To explore the characteristics of chromosome karyotypes in patients with chronic myeloid leukemia (CML), and to provide help individualized treatment. Methods The date 313 FISH 45 these CML excluding Ph negative (Ph-) after treatment were collected from January 2014 June 2015. Karyotypes detected by R-banding. Results In cases, 307 cases (98.08 %) positive (Ph+) 6 (1.92 Ph-. In Ph+ patients, 288 (93.81 classical Ph+, 19 (6.19 variant rearrangements. There 48 (15.34...
Objective To evaluate significance of the quantification bcr-abl mRNA in diagnosis and therapy chronic myeloid leukemia (CML),essentiality for monitoring minimal residual disease. Methods Bcr-abl 518 CML patients were detected using real-time PCR. Results Expression was gradually increased among blastic phase (BP) (12.6 %),accelerated (AP) (25.4 %) (CP) (57.2 (P<0.05). Quantification cut down after allotransplantation becomes normal treatment 6 months. But inpatients treated with imatinib...